Unveiling the origins and genetic makeup of the "forgotten people": A study of the Sarmatian-period population in the Carpathian Basin.

The nomadic Sarmatians dominated the Pontic Steppe from the 3rd century BCE and the Great Hungarian Plain from 50 CE until the Huns' 4th-century expansion. In this study, we present a large-scale genetic analysis of 156 genomes from 1st- to 5th-century Hungary and the Carpathian foothills. Our findings reveal minor East Asian ancestry in the Carpathian Basin (CB) Sarmatians, distinguishing them from other regional populations.

Considerations and Challenges of Resorbable Intramedullary Nailing in Pediatric Forearm Fractures.

: Pediatric diaphyseal forearm fractures, often caused by sports or leisure activities, require treatment based on fracture stability. While stable fractures can be managed conservatively, unstable fractures typically require surgery, with elastic stable intramedullary (IM) nailing (ESIN) being the gold standard. Bioabsorbable IM nails (BINs) offer an alternative by eliminating the need for implant removal surgery.

The Role of Salicylic Acid in Activating Plant Stress Responses-Results of the Past Decade and Future Perspectives.

Salicylic acid (SA) is one of the most commonly used natural plant protection compounds, considered one of the most effective in mitigating the damage caused by abiotic and biotic stressors. The current review article summarizes the most significant achievements in stress management over the past ten years. We also provide insights into new perspectives on the use of salicylic acid.

Epidemiology and Clinical Relevance of in Non-Human Immunodeficiency Virus Patients at a Tertiary Care Center in Central Europe: A 3-Year Retrospective Study.

This study examines the clinical characteristics of pneumonia (PjP) in non-Human immunodeficiency virus (HIV) patients in Hungary to describe its local epidemiological properties. : Our study was conducted at a clinical center with more than 1700 beds at the University of Debrecen in Hungary. We included all patients without HIV infection for whom a diagnostic evaluation for infection had been requested between 1 January 2022 and 31 December 2024.

The Clinical Relevance of Distinguishing Between Simple and Complex Adnexal Cystic Structures by Ultrasound in Peri- and Postmenopause.

: We aimed to determine the reliability of simple ultrasound (US) markers and CA-125 measurements in diagnosing peri- and postmenopausal ovarian masses. : The study was conducted in a retrospective setting. The preoperative imaging properties of peri- (PEM) and postmenopausal (POM) ovarian cysts were examined.

First Report of Infection in Hungary.

is associated with difficult-to-treat, often extensive dermatophytosis and resistance to the commonly used antifungal agents. Successful therapy often necessitates higher than usual doses of systemic therapy for prolonged periods. The spread of this species has gained much attention lately, as several European and other Western hemisphere countries have recently reported their first respective cases or increasing numbers of them.

Close Males Sing With Dissimilar Minimum Frequency and Repertoire Size in a Wild Passerine.

The position occupied in social networks influences the success of individuals in many animal species. However, the associations between bird song (an important means of communication) and the relative position in social networks remained understudied. Such associations are expected because neighbors can learn song elements from each other or change their songs due to competition, and also because song can be related to other individual traits determining social network positions.

Treatment of Pediatric Displaced Intraarticular Olecranon Fractures with Resorbable Poly-L-Lactic-Co-Glycolic Acid (PLGA) Pins and Polydioxanone (PDS) Loops.

Background: Pediatric olecranon fractures, though rare, can be serious. Treatment varies by type and severity; displaced, intraarticular fractures usually need surgery, where biodegradable implants are emerging as an encouraging option to metal hardware.

Methods: Our prospective, single-center, single-arm case series evaluates three pediatric olecranon fracture patients treated by resorbable poly-L-lactic-co-glycolic acid (PLGA) pins and polydioxanone (PDS) loops between Jan 2022 and January 2023 at the Department of Pediatrics, University of Pécs, Clinical Complex.

A comprehensive analysis of the effect of quorum-sensing molecule 3-oxo-C12-homoserine lactone on and .

occupies similar niches in various infections as ; however, the details of their interspecies communication remain largely unknown. To gain deeper insights into this relationship, phenotypic and transcriptomic analyses were conducted in the presence of the primary quorum-sensing molecule, N-(3-oxododecanoyl)-l-homoserine lactone (HSL), against , with the results compared to those of . Our findings indicate that HSL-induced effects are not specific to ; additionally, several characteristics are present in but not in following HSL exposure.

Transcriptome datasets of salt-stressed tomato plants treated with zinc oxide nanoparticles.

Salinity diminishes agricultural productivity and quality, resulting in overall economic losses on a worldwide scale. Zinc oxide nanoparticles (ZnO-NPs) have been found to enhance plant physiological and metabolic processes, as well as increase overall resilience to abiotic stressors. A research study was undertaken to assess the effects of foliar application of chemically produced ZnO-NPs on tomato plants, both in the presence and absence of a NaCl stressor.

Application of Biofire Filmarray Joint Infection Panel for Rapid Identification of Aetiology in a Necrotizing Fasciitis Case.

: Monomicrobial necrotizing fasciitis is associated with exceedingly high mortality rates. Although effective antimicrobial therapy is an important part of treatment, the traditional microbiological diagnostic methods are not fast enough to meaningfully influence early therapeutic decisions. : Here, we report the application of the BioMérieux Biofire Filmarray Joint Infection Panel (BFJIP) for the rapid detection of the causative agent and susceptibility prediction in such a case.

Analysis of Plant Physiological Parameters and Gene Transcriptional Changes Under the Influence of Humic Acid and Humic Acid-Amino Acid Combinations in Maize.

The study investigated the application of humic acids (HAs) and a combination of humic acids and amino acids (HA+AA) in maize under field conditions. Based on preliminary data in the literature, the aim was to investigate the effects of the two plant conditioning compounds on plant physiological parameters. In addition to measuring plant physiological parameters in the field, a complete transcriptome analysis was performed to determine exactly which genes were expressed after the treatments and in which physiological processes they play a role.

Isolate Specific Transcriptome Changes Exerted by Isavuconazole Treatment in Candida auris.

The sudden emergence of multidrug- and pan-resistant Candida auris isolates, combined with limited treatment options, poses significant global challenges in healthcare settings. Combination based therapies are promising alternative options to overcome C. auris related infections, where echinocandin and isavuconazole (ISA) combinations may be an interesting and promising approach.

Multicentric study on the reproducibility and robustness of PET-based radiomics features with a realistic activity painting phantom.

Previously, we developed an "activity painting" tool for PET image simulation; however, it could simulate heterogeneous patterns only in the air. We aimed to improve this phantom technique to simulate arbitrary lesions in a radioactive background to perform relevant multi-center radiomic analysis. We conducted measurements moving a 22Na point source in a 20-liter background volume filled with 5 kBq/mL activity with an adequately controlled robotic system to prevent the surge of the water.

Artefacts on magnetic resonance imaging with Osia®2 bone conduction hearing aid: A cadaver study.

Objectives: Hearing implants often limit the assessment of magnetic resonance examinations due to susceptibility artefacts. Our aim was to evaluate the impact of artefacts attributed to the Osia®2 implant system in terms of utility in visualizing selected cranial structures.

Methods: A BI300 implant and an OSI200 actuator were implanted into a human cadaver head in the audiologically most favourable position according to the manufacturer's guidelines.

Bacteraemia Associated with : A Rare Case Presentation from Hungary.

is a Gram-negative anaerobic bacterium. In current study, it was identified in the bloodstream of a 69-year-old man admitted to the Neurology Clinic at the University of Debrecen, Clinical Centre, Hungary, for internal carotid artery stent implantation. Bacteraemia caused by is extremely rare, with very few cases reported worldwide.

Transcriptome datasets of maize plant cultures treated with humic- and amino acids.

There has been a global surge in the need for commercially accessible plant conditioners that are derived from natural ingredients and are therefore environmentally benign. Currently, sustainable agriculture and minimizing the ecological impact are of great importance. Preparations that contain commonly used humic acids and/or natural amino acids are ideal for meeting these criteria.

Dataset of chemical composition of Avar age glass beads.

Monographic processing of Avar Period (6-8th century) glass beads. Approx. 200 glass beads have been selected from 13 archaeological sites in current day Hungary as the representatives of typical Avar glass beads.

Interventional Effect of Zinc Oxide Nanoparticles with L. Plants When Compensating Irrigation Using Saline Water.

High salinity reduces agriculture production and quality, negatively affecting the global economy. Zinc oxide nanoparticles (ZnO-NPs) enhance plant metabolism and abiotic stress tolerance. This study investigated the effects of 2 g/L foliar Zinc oxide NPs on L.

[Complete blood count at the time of diagnosis is not predictive to survival in prostatic cancer].

Introduction: Numerous observations suggest that several elements of the complete blood count (CBC) predict disease survival in certain cancers. Objective: To evaluate the relationship between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), white blood cell count (WBC) and length of survival in prostate cancer patients. Method: We analyzed the relationship between clinical data (age at diagnosis, prostate-specific antigen [PSA] level, TNM score, Gleason score, comorbidities and CBC elements) and survival time in prostatic cancer patients diagnosed between 2000 and 2005 at the General Urology Department of Uzsoki Street Hospital using Cox regression.

Exposure to an insecticide formulation alters chemosensory orientation, but not floral scent detection, in buff-tailed bumblebees (Bombus terrestris).

Although pesticide-free techniques have been developed in agriculture, pesticides are still routinely used against weeds, pests, and pathogens worldwide. These agrochemicals pollute the environment and can negatively impact human health, biodiversity and ecosystem services. Acetamiprid, an approved neonicotinoid pesticide in the EU, may exert sub-lethal effects on pollinators and other organisms.

Emerging Trends in Non-Protein Amino Acids as Potential Priming Agents: Implications for Stress Management Strategies and Unveiling Their Regulatory Functions.

Plants endure the repercussions of environmental stress. As the advancement of global climate change continues, it is increasingly crucial to protect against abiotic and biotic stress effects. Some naturally occurring plant compounds can be used effectively to protect the plants.

The Influence of Zinc Oxide Nanoparticles and Salt Stress on the Morphological and Some Biochemical Characteristics of L. Plants.

Salinity reduces crop yields and quality, causing global economic losses. Zinc oxide nanoparticles (ZnO-NPs) improve plant physiological and metabolic processes and abiotic stress resistance. This study examined the effects of foliar ZnO-NPs at 75 and 150 mg/L on tomato Kecskeméti 549 plants to alleviate salt stress caused by 150 mM NaCl.