Publications by authors named "Zhuqin Zhan"
The clinical characteristics and genotype analysis of gene mutation.
Front Med (Lausanne)
October 2024
Article Synopsis
- The study reports on a case of steroid-resistant nephrotic syndrome in a 9-month-old infant caused by novel gene mutations, highlighting the clinical and genetic features of Pierson syndrome.
- Retrospective analysis included clinical presentation, genetic mutation features, and prognosis, supported by literature searches in various medical databases.
- The findings revealed specific genetic mutations, common histopathological results, and a trend toward severe outcomes in affected patients, with a significant proportion progressing to end-stage kidney disease.
Objectives: To investigate the effect of dexamethasone (DXM) on acute lung and kidney injury with sepsis and its possible mechanism.
Methods: Control (NC), lipopolysaccharide (LPS) and lipopolysaccharide + dexamethasone (LPS+DXM) treated groups were established by random assignment of 72 Wistar rats. The NC rats were injected with physiological saline, while the LPS group was injected with LPS (5 mg/kg) and LPS+DXM group was injected with LPS(5 mg/kg) first and followed by DXM (1 mg/kg).
To investigate the risk factors for new renal scarring (NRS) in children with vesicoureteral reflux (VUR) receiving continuous antibiotic prophylaxis (CAP). This was a single-center cohort study. The clinical data of 140 children with grade I-V VUR receiving CAP were analyzed.
View Article and Find Full Text PDFRenal abscess complicating acute pyelonephritis in children: Two cases report and literature review.
Medicine (Baltimore)
December 2023
Rationale: To describe the diagnostic and treatment approaches of renal abscesses complicated with acute pyelonephritis in children.
Patient Concerns: Two children presented with fever, vomiting, and abdominal pain with no typical manifestations, like frequent urination, urgency, dysuria, hematuria, foam urine, and lumbago. Renal abscess complicating acute pyelonephritis was diagnosed by B-ultrasound and computed tomography enhancement.