Publications by authors named "Zhousheng Shen"

Photoacoustic microscopy (PAM) uniquely combines optical resolution with ultrasonic penetration capabilities. However, conventional focused Gaussian beam excitation presents inherent limitations in detection visibility and spatial resolution. Although increasing optical NA can partially mitigate these constraints, it inevitably compromises working distance (WD) and depth of field (DoF) and thus poses challenges for large-volume imaging.

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Article Synopsis
  • - Ultrasound coupling is a major challenge in using traditional photoacoustic microscopy (PAM) for clinical examination of chronic wounds.
  • - Photoacoustic remote sensing (PARS) is a promising solution that utilizes all-optical measurements and has shown potential in functional imaging of tissue but needs further exploration in hemodynamic quantification.
  • - The study introduces an all-optical thermal-tagging flowmetry method for PARS Microscopy, demonstrating its effectiveness with high accuracy in measuring blood flow rates from 0 to 12 mm/s without using dyes.
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