Activation of Chlorite with Sunlight for the Efficient Disinfection of Antibiotic-Resistant Bacteria: the Overlooked Contribution of Cytomembrane-Bound Chlorite.

Current antibiotic-resistant bacteria (ARB) disinfection techniques commonly rely on large dosages of oxidants, resulting in the presence of considerable amounts of residuals and toxic disinfection byproducts (DBPs) in water. Herein, we propose a highly effective ARB disinfection approach via activating an ultralow concentration (10 μM) of chlorite (ClO) by naturally abundant sunlight to generate various reactive species (i.e.

Boosting Low-Dose Ferrate(VI) Activation by Layered FeOCl for the Efficient Removal of Antibiotic-Resistant Bacteria and Antibiotic Resistance Genes via Enhancing Fe(IV)/Fe(V) Generation.

Antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in aquatic environments pose threats to ecosystem safety and human health, which could not be efficiently removed by conventional disinfection techniques. Herein, layered FeOCl with coordinatively unsaturated Fe sites were fabricated and used to activate Fe(VI) for the efficient ARB/ARG removal in the present study. We found that highly reactive Fe(IV)/Fe(V) intermediates were generated in the FeOCl/Fe(VI) system, rapidly disinfecting 1 × 10 CFU mL ARB to below the limit of detection within only 6 min.

The protective role of vitamin B1 in alcohol related headaches induced by disturbance of blood flow and direct cytotoxicity to hippocampal neuron.

Objectives: To evaluate vitamin B1 in alcohol-induced headaches and elucidate its underlying mechanisms and potential preventive applications.

Methods: In vitro cellular assays assessed the cytotoxicity of alcohol and the protective effects of vitamin B1 on components of the mouse neurovascular units, including endothelial cells, astrocytes, and neurons. Murine models were used to study the effects of alcohol on cerebral blood flow and neurons, as well as the neuroprotective efficacy of vitamin B1.

Arthroscopic Trianchor With 6 Sets of Double-Pulley Suture Bridge Repair of Medium-Sized Supraspinatus Tendon Tears.

Currently, a suture bridge is a good way to treat medium-sized supraspinatus tendon tears. However, one medial-row anchor (double-loaded suture anchor) can only create 4 sets of suture-bridges, and overtension and reduced blood flow in the tendon caused by the knotted medial-row may lead to tendon retear. Therefore, we present a pragmatic suture-bridge technique called the trianchor double-pulley suture-bridge (DPSB).

Imperfect hydroxyapatite bioceramics derived from golden pomfret have enhanced osteogenic properties.

Imperfect hydroxyapatite (IHA) bioceramics, which contain defects such as calcium deficiency, carbonate substitution, and metal cation substitution, exhibit improved osteogenic properties. In this study, we used a two-step calcination-hydrothermal process to manufacture two types of golden pomfret bone-derived imperfect hydroxyapatite bioceramics (G-IHA): carbonated calcium-deficient hydroxyapatite (CD-IHA) and carbonated hydroxyapatite (C-IHA). Their composition, surface morphology, zeta potential, degradation capacity, mineralization and osteogenic properties were systematically investigated.

Arthroscopic Double-Pulley Suture-Bridge Repair of Partial Articular Supraspinatus Tendon Avulsions >1.5 cm Using One Medial-Row Anchor.

Currently, transtendon repair with 2 medial-row anchors is a popular treatment for PASTA (partial articular supraspinatus tendon avulsion) lesions with tear sizes greater than 1.5 cm; however, the shortcoming is too much tissue trauma on the bursal layer. In this Technical Note, we present the double-pulley suture bridge mini-incision transtendon (trianchor "mini-incision" transtendon) technique.

Arthroscopically Assisted Acromioclavicular Joint Reconstruction With 2.0-mm Tunnel in the Clavicle and Suture Looping Around the Coracoid Process.

Arthroscopic acromioclavicular joint (ACJ) reconstruction is widely applied in ACJ dislocation. A 4.0-mm bone tunnel is the most used size in the clavicle; drilling a bone tunnel in the coracoid process is also commonly applied.

Arthroscopic "Mini-Incision" Transtendon Repair Combined With Tri-Anchor Double-Pulley Suture-Bridge Repair of PASTA Lesion.

Currently, transtendon repair is a popular way to treat PASTA (partial articular supraspinatus tendon avulsion) lesions. However, tendon trauma on the bursal layer, which may cause tendon retear, is a defect of transtendon repair. Arthroscopic "mini-incision" transtendon repair combined with tri-anchor double-pulley suture-bridge (DPSB) repair is a pragmatic surgical technique.

Physiological and transcriptomic analysis of Spartina alterniflora in response to imazapyr acid stress.

As a key aspect of managing of invasive alien species in China, the prevention and control of Spartina alterniflora have become an important part of the work in coastal provinces, and imazapyr acid has been gradually applied in the control work due to its advantages of high efficiency and low toxicity. In this study, we applied 6.0 L/acre of 25% imazapyr acid aqueous stress treatment, and determined and analyzed the physiological activities and transcriptome profiles of S.

Arthroscopic 4-Anchor Double-Pulley Suture-Bridge Repair of Large Rotator Cuff Tear.

Currently, suture bridge (SB) is a popular way to treat large rotator cuff tears. However, the restricted number of sutures used for tendon fixation, the knotted medial row, and the excessive number of tendon holes created from suture hook piercing are the shortcomings of SB repair. Arthroscopic 4-anchor double-pulley suture-bridge (DPSB) repair is a pragmatic surgical technique and can overcome these shortcomings of SB repair.

Arthroscopic Tri-anchor Double-Pulley Suture-Bridge Reduction of Greater Tuberosity Fracture.

Currently, cannulated screws, plates, and suture bridges are widely applied in the treatment of greater tuberosity fracture; however, further fragmentation of the fracture, risk of loss of fracture reduction, implant impingement, and anchor pullout are the drawbacks. Therefore, we present a pragmatic surgical technique called the arthroscopic tri-anchor double-pulley suture-bridge technique that uses a double-loaded metallic anchor as a lateral-row anchor. In the treatment of greater tuberosity fracture, this hybrid repair including 4 sets of double-pulley suture bridges and 2 sets of single rows can obtain powerful stiffness of the suture construct, the metallic anchor used as a lateral-row anchor can significantly reduce the risk of anchor pullout, the single-row process can lessen the overall surgical time, and implant impingement will not occur postoperatively.

Building a Confluence Charge Transfer Pathway in COFs for Highly Efficient Photosynthesis of Hydrogen Peroxide from Water and Air.

Sunlight-driven photosynthesis by covalent organic frameworks (COFs) from water and air without using sacrificial reagents is a promising HO fabrication approach but is still restricted by the insufficient charge separation and sluggish 2e water oxidation process. Herein, we provide a facile strategy to simultaneously improve charge separation and water oxidation in COFs via confining the charge transfer pathways from two diversion ones to a confluence one through regulating the site of nitrogen in bipyridine. Combining in-situ characterization with computational calculations, we reveal that compared to COF-BD1 containing two diversion charge transfer pathways, the charge transfer pathway in COF-BD2 is confined to a confluence due to the electron-deficiency effect of nitrogen, which greatly accelerates the intermolecular and out-of-plane charge transfer.

Green and efficient disinfection of antibiotic-resistant bacteria via PI/HO homogeneous system.

The proliferation and spread of antibiotic-resistant bacteria (ARB) significantly threaten human health and ecosystem. Periodate (PI) based advanced oxidation process has potentials for water purification but is limited by complex activators or activation process. Herein, we demonstrated that HO could be used to activate PI, achieving efficient ARB disinfection performance.

Arthroscopic V-Shaped Double-Pulley Suture-Bridge Repair of Massive Rotator Cuff Tear.

At present, suture bridge is a feasible choice in the treatment of massive rotator cuff tears (MRCTs). However, high tension on the repair site and medial tension during suture tightening and after medial knotting are unavoidable problems in MRCT repair with a suture bridge. Arthroscopic V-shaped double-pulley suture-bridge repair is a pragmatic surgical technique for the repair of MRCTs.

"Mini-Incision" Transtendon Double-Pulley Suture-Bridge Repair of PASTA Lesion.

Transtendon repair is increasingly applied in the treatment of PASTA (partial articular supraspinatus tendon avulsion) lesions, but a "tendon hole" from anchor insertion, which will break the intact bursal layer and potentially result in tear completion, is an unavoidable problem. The "mini-incision" transtendon double-pulley suture bridge presented in the study is a pragmatic technique in treatment of PASTA lesion. The 4 suture strands on the medial-row anchor provide enough biomechanical strength on the reattached articular layer, the "mini-incision" minimizes iatrogenic trauma on the bursal layer, and double-pulley suture-bridge smoothly covers the "mini-incision" so as to achieve anatomical reduction of articular and bursa side of supraspinatus tendon.

Oxygen vacancy-dependent synergistic disinfection of antibiotic-resistant bacteria by BiOBr nanoflower induced HO activation.

Antibiotic-resistant bacteria (ARB) and antibiotic-resistant genes (ARGs) pose a significant threat to both ecosystems and human health. Owing to the excellent catalytic activity, eco-safety, and convenience for defect engineering, BiOBr with oxygen vacancies (OVs) of different density thus were fabricated and employed to activate HO for ARB disinfection/ARGs degradation in present study. We found that BiOBr with OVs of appropriate density induced via ethanol reduction (BOB-E) could effectively activate HO, achieving excellent ARB disinfection and ARGs degradation efficiency.

Rigid covalent organic frameworks with thiazole linkage to boost oxygen activation for photocatalytic water purification.

Owing to their capability to produce reactive oxygen species (ROS) under solar irradiation, covalent organic frameworks (COFs) with pre-designable structure and unique architectures show great potentials for water purification. However, the sluggish charge separation, inefficient oxygen activation and poor structure stability in COFs restrict their practical applications to decontaminate water. Herein, via a facile one-pot synthetic strategy, we show the direct conversion of reversible imine linkage into rigid thiazole linkage can adjust the π-conjugation and local charge polarization of skeleton to boost the exciton dissociation on COFs.

Simultaneous inactivation of Microcystis aeruginosa and degradation of microcystin-LR in water by activation of periodate with sunlight.

Harmful algal blooms pose tremendous threats to ecological safety and human health. In this study, simulated solar light (SSL) irradiation was used to activate periodate (PI) for the inactivation of Microcystis aeruginosa and degradation of microcystin-LR (MC-LR). We found that PI-SSL system could effectively inactivate 5 × 10 cells·mL algal cells below the limit of detection within 180 min.

Efficient Photosynthesis of Hydrogen Peroxide by Cyano-Containing Covalent Organic Frameworks from Water, Air and Sunlight.

The insufficient exciton (e -h pair) separation/transfer and sluggish two-electron water oxidation are two main factors limiting the H O photosynthetic efficiency of covalent organic frameworks (COFs) photocatalysts. Herein, we present an alternative strategy to simultaneously facilitate exciton separation/transfer and reduce the energy barrier of two-electron water oxidation in COFs via a dicyano functionalization. The in situ characterization and theoretical calculations reveal that the dicyano functionalization improves the amount of charge transfer channels between donor and acceptor units from two in COF-0CN without cyano functionalization to three in COF-1CN with mono-cyano functionalization and four in COF-2CN with dicyano functionalization, leading to the highest separation/transfer efficiency in COF-2CN.

Dynamic monitoring and analysis of chlorophyll-a concentrations in global lakes using Sentinel-2 images in Google Earth Engine.

Remote estimation of Chlorophyll-a (Chl-a) has long been used to investigate the responses of aquatic ecosystems to global climate change. High-spatiotemporal-resolution Sentinel-2 satellite images make it possible to routinely monitor and trace the spatial distributions of lake Chl-a if reliable retrieval algorithms are available. In this study, Sentinel-2 images and in-situ measured data were used to develop a Chl-a retrieval algorithm based on 13 optical water types (OWTs) with a satisfying performance (R = 0.

Efficient As(III) removal from water by ZrO modified covalent organic framework under visible light irradiation.

Adsorption-oxidation is a promising technique to decontaminate As(III) polluted water. In present study, ZrO-modified covalent organic framework (ZrO-COF) was fabricated and used to remove arsenic from water under visible light irradiation. The results showed that ZrO-COF (0.

Nanoplastics increase the adverse impacts of lead on the growth, morphological structure and photosynthesis of marine microalga Platymonashelgolandica.

Nanoplastics and heavy metals are common pollutants in coastal environments with high concerns, but their joint ecological risk to marine primary productivity remains unclear. In this study, the effects of 7, 70, 700 μg/L lead (Pb) single exposure and in combination with 200 μg/L polystyrene nanoplastics (NPs, 70 nm) on marine microalga Platymonas helgolandica were investigated. Pb single exposure induced a dose-dependent inhibition on the growth of P.

Boosting Exciton Dissociation and Charge Transfer in Triazole-Based Covalent Organic Frameworks by Increasing the Donor Unit from One to Two for the Efficient Photocatalytic Elimination of Emerging Contaminants.

As novel photocatalysts, covalent organic frameworks (COFs) have potential for water purification. Insufficient exciton dissociation and low charge mobility in COFs yet restricted their photocatalytic activity. Excitonic dissociation and charge transfer in COFs could be optimized via regulating the donor-acceptor (D-A) interactions through adjusting the number of donor units within COFs, yet relevant research is lacking.

Ideal entry point and direction of retrograde intramedullary nailing of the tibia.

Purpose: To determine the ideal entry point and direction of retrograde intramedullary nailing of the tibia.

Methods: The imaging data of patients with distal tibial fractures from June 2020 to December 2021 in our hospital were collected, and computer-aided design was performed. The relevant data were imported into the software for processing, so as to obtain a distal tibial fracture model and simulate the retrograde intramedullary nail placement in the tibia.

Novel, high accuracy models for hepatocellular carcinoma prediction based on longitudinal data and cell-free DNA signatures.

Background & Aims: Current hepatocellular carcinoma (HCC) risk scores do not reflect changes in HCC risk resulting from liver disease progression/regression over time. We aimed to develop and validate two novel prediction models using multivariate longitudinal data, with or without cell-free DNA (cfDNA) signatures.

Methods: A total of 13,728 patients from two nationwide multicenter prospective observational cohorts, the majority of whom had chronic hepatitis B, were enrolled.