Optical rotation and cell control based on the LP21 mode and a tapered microcavity optical waveguide.

This paper innovatively proposes a single-fiber optical tweezers probe based on a tapered microcavity optical waveguide. This design leverages the dual characteristics of the fiber LP21 mode to achieve dual-mode, high-precision rotational manipulation of cells: on one hand, by precisely controlling the fiber twist angle, the LP21 mode spot can be rotated regularly, driving cells trapped by the optical tweezers on the outer wall of the tapered microtube to undergo controlled "orbital rotation" along the tube wall in the y-z plane; on the other hand, by adjusting the fiber stretching degree to modulate the LP21 mode spot energy distribution, the multi-physical fields (including optical, flow fields, etc.) at the microtube port are altered, inducing an optically induced vortex to drive cells at the port to perform controlled "spin rotation" in the x-y plane.

Radial rotation of cell-pair under beam mode coupling effect of microcavity cascaded single fiber optical tweezers.

This article presents a control method for radial cell-pair rotations using a single-fiber manipulation technique that combines microcavity cascade optical tweezers with optical fiber mode coupling technology. It explores the mechanisms of cell manipulation under the influence of mode coupling and capillary fluid forces. By controlling the angle of fiber twisting and utilizing the birefringence effect along with the principle of beam mode coupling, it is possible to achieve precise and regular variations in the energy of the LP21 mode beam spot, thereby altering the magnitude and direction of the forces acting on the cell-pair, which induces a tendency for rotational motion.

Collective transport of particles and cells enabled by wavelength-division multiplexing in microcavity cascade optical tweezers.

This study presents a microcavity cascade optical tweezer (MCOT) system incorporating wavelength-division multiplexing for collective transport of particles and cells in biomedical applications. The MCOT system traps and transports yeast cells (5 μm) and silica microspheres using 980 nm and 1550 nm lasers, with a maximum capacity of six particles. Under 980 nm laser illumination, capillary microflow force surpasses optical forces, stably trapping particles and cells in the microcavity.

New applications of the existence of solutions for equilibrium equations with Neumann type boundary condition.

Using the existence of solutions for equilibrium equations with a Neumann type boundary condition as developed by Shi and Liao (J. Inequal. Appl.