Successful Diagnosis and Treatment of Early Postpartum Choriocarcinoma.

Background: Postpartum placental choriocarcinoma is a rare gestational trophoblastic tumor, with an incidence of approximately one in 50 000. Patients often present with persistent postpartum hemorrhage, which can lead to delayed diagnosis, hematogenous metastasis, and ultimately, a poor prognosis.

Case: A 35-year-old woman was admitted to the Emergency Department 39 days after a cesarean section due to persistent heavy vaginal bleeding.

Composite dietary antioxidant index and infertility: A study based on NHANES 2013 to 2018.

The Composite Dietary Antioxidant Index (CDAI), a robust metric reflecting the antioxidant richness of one's diet, has garnered attention for its capacity to temper the progression of a plethora of chronic maladies: among them, chronic obstructive pulmonary disease, chronic kidney disease, depression, nephrolithiasis (kidney stones), and papillomavirus infections. Its established role as a guardian against such conditions notwithstanding, the association between CDAI and reproductive health, particularly infertility, has yet to be thoroughly delineated. Against this backdrop, our research endeavor aims to explore the potential correlation between CDAI scores and the prevalence of infertility, thereby contributing to the existing knowledge base on the multifaceted impacts of dietary antioxidants on human health.

5-Methylcytosine methylation predicts cervical cancer prognosis, shaping immune cell infiltration.

BackgroundEpigenetics, encompassing DNA and RNA modifications, has emerged as a prominent area of research in the post-genomic era. Numerous studies have elucidated the impact of epigenetics on tumor regulation. However, the methylation patterns of 5-methylcytosine in cervical cancer as well as its role in the tumor microenvironment and immunotherapy remain poorly understood.

Association between urinary arsenic and the prevalence of endometriosis in women in the United States.

Background: Endometriosis affects up to 15% of women of reproductive age and can lead to various symptoms. More than 200 million people worldwide are at risk of higher than safe levels of arsenic exposure through drinking water. Studies investigating the relationship between arsenic and endometriosis are very limited and have yielded inconsistent results.

Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.

Background: Medroxyprogesterone acetate (MPA), a synthetic progestogen, is extensively used for the treatment of various conditions, including contraception, irregular menstruation, functional uterine bleeding, and endometriosis. However, like all pharmaceutical agents, MPA is associated with adverse drug reactions. This study aimed to evaluate the adverse events (AEs) associated with MPA in by analyzing real-world data from the U.

Fertility-preserving treatment in patients with early-stage endometrial cancer: A protocol for systematic review and meta-analysis.

Background: Endometrial cancer (EC) is the second most common malignancy of the female reproductive system worldwide, and the standard treatment for early-stage EC potentially leads to permanent infertility. The objective of this study was to investigate the efficacies of different methods on fertility preservation in patients with early-stage EC.

Methods: We searched the major online databases (PubMed, Embase, The Cochrane Library, and Web of Science) to collect the research literature on fertility preservation therapy in patients with early-stage well-differentiated EC aged ≤ 40 years from January 1999 to October 2019.

Small cell carcinoma of the cervix complicated by syndrome of inappropriate antidiuretic hormone secretion: a case report.

Small cell carcinoma of the cervix is a rare malignant tumor in the clinical setting. Clinical manifestations of this tumor are mostly similar to those of normal types of cervical cancer. Small cell carcinoma of the cervix only shows symptoms of neuroendocrine tumors, such as syndrome of inappropriate antidiuretic hormone secretion (SIADH).

CARE-Placental site trophoblastic tumor presenting with thrombotic microangiopathy: A case report.

Rationale: Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic neoplasm (GTN).

Patient Concerns: A 28-year-old Chinese female with initial presentation of thrombotic microangiopathy (TMA) with symptoms of edema of the lower extremities and eyelid, thrombocytopenia and anemia.

Diagnoses: The primary diagnosis was chronic glomerulonephritis according to the related laboratory tests and clinical symptoms.