A 3D Nanofiltration Array for Direct Plasma EV Purification with Label-Free SERS Detection toward Accurate Clinical Breast Cancer Staging.

Extracellular vesicles (EVs) have emerged as promising biomarkers in cancer diagnostics. However, rapid and nondestructive isolation of EVs from plasma remains challenging due to the presence of abundant interferents with smaller sizes (e.g.

A safety risk assessment method for TBM tunnel construction based on attribute interval identification theory.

Based on the identification and analysis of safety risks in TBM tunnel construction, we construct a comprehensive safety risk dynamic evaluation index system tailored to this context. To account for the dynamic nature of safety risks during TBM tunnel construction, variable weight theory is incorporated, allowing for a more accurate reflection of the time-varying importance of risk indicators. Building on the theoretical framework of attribute interval recognition theory, we establish a TBM tunnel construction safety risk evaluation model grounded in attribute interval theory.