Publications by authors named "Yun-Yu Wei"
Elevated serum YKL-40 correlates with clinical characteristics in patients with polymyositis or dermatomyositis.
Ann Clin Biochem
January 2019
Article Synopsis
- Serum YKL-40 is a potential biomarker for assessing the disease activity in polymyositis and dermatomyositis, which were previously unexplored areas for this biomarker.
- In a study with 99 patients, those affected by these conditions had higher levels of YKL-40 compared to healthy controls, and especially higher levels were found in patients with interstitial lung disease.
- The results indicate that serum YKL-40 correlates with several disease activity markers and can effectively help identify interstitial lung disease in affected patients.
Effect of different zinc sources and levels on inhibition of the apoptosis induced by glucocorticoid of thymocytes in vitro.
Biol Trace Elem Res
November 2005
This experiment was conducted to investigate the effects of zinc sulfate and zinc methionine (Zn-Met) and their levels on apoptosis induced by glucocorticoid of thymocytes and the possible mechanism. Dexamethasone was used to make the apoptosis model of thymocytes; zinc sulfate and zinc methionine were supplemented to the medium at levels of 0, 50, 100, 500, and 1000 microM. The activity of cells, Cu,Zn superoxide dismutase (Cu,Zn-SOD), DNA ladder pattern, intracellular calcium concentration, and the percentage of apoptosis nuclei were determined.
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