Publications by authors named "Yun-Jin Bai"

Background: Gout and hyperuricemia, driven by elevated uric acid (UA). Circadian syndrome (CircS), a cluster of cardiometabolic risk factors related to circadian disruption, may interact with these conditions, but evidence remains limited. Understanding the potential associations of CircS with gout and hyperuricemia is crucial for effective health interventions.

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Article Synopsis
  • Urothelial carcinoma (UC) is tough to treat with surgery, but antibody-drug conjugates (ADCs) show promise as targeted therapies, despite limited randomized control trials.
  • A systematic review analyzed 12 studies involving 1,311 patients, revealing an overall response rate (ORR) of 40% and a disease control rate (DCR) of 74%, with median progression-free survival (PFS) of 5.66 months and overall survival (OS) of 12.63 months.
  • Common treatment-related adverse events (TRAEs) included alopecia, decreased appetite, and fatigue, but the overall safety profile of ADCs seems favorable for advanced or metastatic UC patients
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Article Synopsis
  • The circadian rhythm is like an internal clock in our bodies that helps control many important functions, and it helps us adapt to changes in our environment.
  • When this internal clock gets messed up, it can cause health problems, including kidney stones.
  • Researchers found links between disrupted circadian rhythms and kidney stone disease, but they still need to study exactly how they are connected and are looking into treatments that can help.
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Urinary stone is conceptualized as a chronic metabolic disorder punctuated by symptomatic stone events. It has been shown that the occurrence of calcium oxalate monohydrate (COM) during stone formation is regulated by crystal growth modifiers. Although crystallization inhibitors have been recognized as a therapeutic modality for decades, limited progress has been made in the discovery of effective modifiers to intervene with stone disease.

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Purpose: Many studies identified that the preoperative neutrophil-to-lymphocyte ratio (PNLR) was associated with patient prognosis in non-muscle-invasive bladder cancer (NMIBC). We hypothesized that PNLR could be prognostic in patients with histological variants of NMIBC (VH-NMIBC).

Materials And Methods: This retrospective study included patients with VH-NMIBC admitted at our center between January 2009 and May 2019.

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Rationale: There are already several reports concerning the occurrence of urethral diverticulum (UD) in female patients, but only rarely has a article describing UD combined with UD calculi or squamous carcinoma been published. Moreover, a case with squamous carcinoma and UD calculi at the same time has never been reported, making this the first case report about this condition.

Patient Concerns: A 43-year-old woman presented to the gynaecology department with a complaint of a hard mass beneath the anterior vaginal wall.

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Objective: To investigate the effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on the recurrence of non-muscle-invasive bladder cancer (NMIBC).

Methods: Clinical data of 388 patients with NMIBC undergoing transurethral resection of bladder tumor during Jan. 2009 to Dec.

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The purpose of the present study was to conduct a meta-analysis of cross-sectional studies assessing the relationship between alcohol consumption and the risk of erectile dysfunction (ED). To identify relevant studies, databases such as Pubmed, Medline, Embase, and the Cochrane Library were searched from the inception of the present study to March 2016. Finally, 24 studies (154,295 patients) were included.

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Objective: To evaluate the clinical efficacy and safety of simple tumor enucleation (TE) for clinical T1 renal cell carcinoma.

Materials And Methods: A systematic search of PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases was performed to identify all trials that compared TE and traditional partial nephrectomy (PN) for patients with clinical T1 renal cell carcinoma.

Results: A total of 7 studies involving 3,218 patients were identified and included in this meta-analysis.

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Objective: To detect circulating tumor cells (CTCs) in peripheral blood from the patients with bladder cancer using subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH) and to explore the relation between CTCs detection result and the clinicpathological parameters of tumors.

Methods: Sixteen patients [(66.88±8.

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Objective: To investigate the feasibility of autologous bone marrow mesenchymal stem cells(BMSCs) seeded on bladder acellular matrix graft (BAMG) for bladder reconstruction in a canine model.

Methods: This study included 25 mongrel dogs. Five dogs were sacrificed for the preparation of BAMG.

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Purpose: To evaluate the efficacy and safety of monopolar (M-TURP) and bipolar (B-TURP) transurethral resection of the prostate in benign prostatic hypertrophy (BPH) patients.

Materials And Methods: Eligible randomized controlled trials (RCTs) were identified from electronic databases without language restrictions. Database search, quality assessment, and data extraction were independently performed.

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