Background: Gout and hyperuricemia, driven by elevated uric acid (UA). Circadian syndrome (CircS), a cluster of cardiometabolic risk factors related to circadian disruption, may interact with these conditions, but evidence remains limited. Understanding the potential associations of CircS with gout and hyperuricemia is crucial for effective health interventions.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2023
Signal Transduct Target Ther
January 2023
Urinary stone is conceptualized as a chronic metabolic disorder punctuated by symptomatic stone events. It has been shown that the occurrence of calcium oxalate monohydrate (COM) during stone formation is regulated by crystal growth modifiers. Although crystallization inhibitors have been recognized as a therapeutic modality for decades, limited progress has been made in the discovery of effective modifiers to intervene with stone disease.
View Article and Find Full Text PDFInvestig Clin Urol
November 2021
Purpose: Many studies identified that the preoperative neutrophil-to-lymphocyte ratio (PNLR) was associated with patient prognosis in non-muscle-invasive bladder cancer (NMIBC). We hypothesized that PNLR could be prognostic in patients with histological variants of NMIBC (VH-NMIBC).
Materials And Methods: This retrospective study included patients with VH-NMIBC admitted at our center between January 2009 and May 2019.
Medicine (Baltimore)
August 2019
Rationale: There are already several reports concerning the occurrence of urethral diverticulum (UD) in female patients, but only rarely has a article describing UD combined with UD calculi or squamous carcinoma been published. Moreover, a case with squamous carcinoma and UD calculi at the same time has never been reported, making this the first case report about this condition.
Patient Concerns: A 43-year-old woman presented to the gynaecology department with a complaint of a hard mass beneath the anterior vaginal wall.
Sichuan Da Xue Xue Bao Yi Xue Ban
July 2018
Objective: To investigate the effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on the recurrence of non-muscle-invasive bladder cancer (NMIBC).
Methods: Clinical data of 388 patients with NMIBC undergoing transurethral resection of bladder tumor during Jan. 2009 to Dec.
Int J Impot Res
November 2018
The purpose of the present study was to conduct a meta-analysis of cross-sectional studies assessing the relationship between alcohol consumption and the risk of erectile dysfunction (ED). To identify relevant studies, databases such as Pubmed, Medline, Embase, and the Cochrane Library were searched from the inception of the present study to March 2016. Finally, 24 studies (154,295 patients) were included.
View Article and Find Full Text PDFObjective: To evaluate the clinical efficacy and safety of simple tumor enucleation (TE) for clinical T1 renal cell carcinoma.
Materials And Methods: A systematic search of PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases was performed to identify all trials that compared TE and traditional partial nephrectomy (PN) for patients with clinical T1 renal cell carcinoma.
Results: A total of 7 studies involving 3,218 patients were identified and included in this meta-analysis.
Sichuan Da Xue Xue Bao Yi Xue Ban
July 2017
Objective: To detect circulating tumor cells (CTCs) in peripheral blood from the patients with bladder cancer using subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH) and to explore the relation between CTCs detection result and the clinicpathological parameters of tumors.
Methods: Sixteen patients [(66.88±8.
Sichuan Da Xue Xue Bao Yi Xue Ban
January 2015
Objective: To investigate the feasibility of autologous bone marrow mesenchymal stem cells(BMSCs) seeded on bladder acellular matrix graft (BAMG) for bladder reconstruction in a canine model.
Methods: This study included 25 mongrel dogs. Five dogs were sacrificed for the preparation of BAMG.
Purpose: To evaluate the efficacy and safety of monopolar (M-TURP) and bipolar (B-TURP) transurethral resection of the prostate in benign prostatic hypertrophy (BPH) patients.
Materials And Methods: Eligible randomized controlled trials (RCTs) were identified from electronic databases without language restrictions. Database search, quality assessment, and data extraction were independently performed.