Spatial, temporal and demographic distribution characteristics of adenomyosis symptom clusters from the perspective of traditional Chinese medicine: a multicenter cross-sectional study in China from 2020 to 2022.

Objective: This study aimed to explore the differences in symptom clusters of adenomyosis (AM) patients across spatial, temporal, and age-stratified dimensions based on the theory of "Treatment in Accordance with Three Categories of Etiologic Factors".

Methods: A cross-sectional study was conducted in China from 2020 to 2022, involving 1,816 AM patients. Univariate analysis, symptom co-occurrence matrices, and hierarchical clustering were used to compare clinical and symptom cluster characteristics across different latitudes (low latitude area: 691 cases vs.

Analysis of dysmenorrhea-related factors in adenomyosis and development of a risk prediction model.

Objective: To explore factors related to dysmenorrhea in adenomyosis and construct a risk prediction model.

Methods: A cross-sectional survey involving 1636 adenomyosis patients from 37 hospitals nationwide (November 2019-February 2022) was conducted. Data on demographics, disease history, menstrual and reproductive history, and treatment history was collected.