Publications by authors named "Yosuke Ishii"

Background: Flatfoot causes the medial shift of ground reaction force during the stance phase of gait, which is associated with various foot disorders. To prevent this shift in flatfoot, it is necessary to understand the characteristics of the loading pattern and what foot joint kinematics influence it. We investigated differences in the center of pressure (COP) position between normal foot and flatfoot, and predictors of COP trajectory during gait.

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Background: Lateral wedge insole (LWI) is known to reduce abnormal mechanical stress in knee osteoarthritis; however, clinical improvement across cases varies. The increase in medial meniscal extrusion (⊿MME) during walking could describe the dysfunction of shock absolution and the reaction of mechanical stress in individual knee joints.

Objective: This study aimed to investigate whether the ⊿MME affects LWI responders.

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Background: The infrapatellar fat pad (IFP) plays the knee joint's buffers capacity based on flexible morphological changes under mechanical stress. Patients who underwent anterior cruciate ligament (ACL) reconstruction have insufficient IFP flexibility; however, morphological change under mechanical stress is still unknown.

Research Question: This study aimed to investigate the morphological change in IFP (ΔIFP) during walking and their correlation with mechanical stress in patients who underwent ACL reconstruction.

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Surgical repair of thoracoabdominal aortic aneurysms (TAAA) is a complex procedure that is associated with marked morbidity and mortality. Endovascular TAAA repair, initially reserved for patients at high risk, has yielded promising results and is performed on an increasing range of patients. This case report describes a hybrid approach-a combination of endovascular and open repair-for a patient with high-risk TAAA after aortic dissection.

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The combination of initial Impella therapy, Impella-supported coronary artery bypass grafting (ISCAB), and postoperative Impella therapy providing antegrade perfusion in myocardial infarction can prove effective. We investigated strategies for Impella stabilization in ISCAB, particularly during peripheral circumflex branch anastomosis. Case 1 was a 70-year-old man treated with an Impella 2.

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Background: Increased medial meniscal extrusion (MME) under mechanical stress is a risk factor associated with progression of knee osteoarthritis (OA). Patients with knee OA often have unique features of abnormal kinematics during squatting, which might induce joint loading and increased MME; however, the detailed relationships involved remains unknown.

Research Question: In this study, we investigated the effects of knee kinematics on increased MME during squatting in patients with knee OA.

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Upper extremity position affects maximum pinch strength; however, there is no consensus regarding the posture of the three ulnar fingers during pinch strength testing, and existing studies have different flexion or extension posture, depending on the measurement method used. This study aimed to clarify the effect of ulnar finger posture on maximum pinch strength and to verify its reliability. Thirty-three participants (19 males and 14 females) performed maximum pulp-to-pulp pinching with both dominant and non-dominant hands.

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The venous cuff technique has been used primarily for arterial bypass using artificial grafts to the lower extremities. The boat-form vein cuff was designed to allow adjustment of the size and angle of the anastomosis at any anatomic site. We report our experience and outcomes of the original vein cuff technique in various peripheral artery bypass grafting procedures.

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Hip joint contact force (HJCF) overloading is a primary mechanical cause of hip osteoarthritis. Hip adduction moment (HAM) is a surrogate measure for estimating HJCF. Gait modification, especially wider step-width (SW), can significantly decrease the peaks and impulses of HAM, suggesting a possible strategy for preventing joint overloading.

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Introduction: Initially, unresectable locally advanced colorectal cancers are still not uncommon. Despite recently developed systemic treatment has extended the survival of patients with unresectable and recurrent disease, surgical resection offers the chance for a cure or long-term survival. Recently, with improvement in the safety of major vascular reconstruction, several reports have suggested that extended pelvic tumor resection with vascular reconstruction with curative intent can be performed safely; however, the indications for arterial vascular reconstruction remain controversial and are reported with a literature review.

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Objective: Atrial tachyarrhythmias are the most frequent complication after the maze procedure. We examined the mechanism of atrial tachyarrhythmias in association with the ablation energy and technique used at each lesion and by the findings of postoperative electrophysiological study.

Methods: Four-hundred fifty-three patients who underwent the maze procedure with biatrial incisions and bilateral pulmonary vein (PV) isolation were examined for the incidence and mechanism of recurrence of atrial fibrillation (AF) and development of atrial tachycardia (AT).

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Purpose: The infrapatellar fat pad (IFP) absorbs mechanical stress in the knee joint owing to flexible morphological changes. The IFP is a key factor in knee osteoarthritis (OA); however, its dynamic feature during walking remains unknown. This study aimed to investigate whether the morphological changes in the IFP during walking involve specific features for patients with knee OA.

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This study aimed to quantitatively evaluate peripheral nerve injury (PNI) after varicose vein (VV) surgery using endovenous laser ablation (EVLA). Overall, 25 cases were analyzed. All patients underwent EVLA of the great saphenous vein (GSV) with or without resection of the varix of the GSV tributaries in stab and avulsion fashion (microphlebectomy).

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This study investigates whether 17β-estradiol (E2), a natural estrogen and one of the endocrine-disrupting chemicals responsible for water pollution, can be oxidatively decomposed under simulated solar light using a composite of tin oxide nanoparticles and graphene-like carbon nitride (g-CN) as a photocatalyst. The composite photocatalyst was prepared by heating a mixture of urea and tin acetate. FT-IR measurements revealed that g-CN possesses structural units similar to g-CN, a well-studied graphite-like carbon nitride.

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Aim Older inpatients have reduced physical function and walking ability with a higher risk of falls after being discharged home. Gait variability can assess ambulation and is strongly related to the risk of falls. However, the clinical factors affecting gait variability in inpatients have not been identified.

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Objectives: Heart failure patients with reduced ejection fraction are currently treated with four drug combinations: angiotensin receptor/neprilysin inhibitors, beta-blockers, mineralocorticoid receptor antagonists, and sodium-glucose cotransporter 2 inhibitors, resulting in improved survival outcomes. Herein, we examined whether myocardial protection by esaxerenone or sacubitril/valsartan may present a counter-effect to the harm caused by cardioplegic arrest.

Methods: Male Wistar rats fed a normal diet were orally administered esaxerenone (3 mg/kg; Esax) or sacubitril/valsartan (68 mg/kg; SaV) once a day for 2 weeks from 6 weeks of age.

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A 43-year-old man diagnosed with a giant retroperitoneal tumor with suspected invasion of the abdominal aorta and inferior vena cava underwent surgery. Complete en bloc tumor resection could be achieved by transection and reconstruction of the abdominal aorta and inferior vena cava. This case highlights the need for aggressive, complete tumor resection when major vessels are invaded.

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Cardiac neoplasms may cause life-threatening symptoms associated with cerebral infarction, ventricular arrhythmias, and heart failure. Emergency surgery or preoperative treatment may be required for these patients. However, no study has reported the surgical outcomes in cases involving cardiac neoplasms with life-threatening complications.

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Article Synopsis
  • Thromboembolism is a critical concern in patients undergoing endovascular treatment for ruptured cerebral aneurysms, and administering antiplatelet agents like aspirin before the procedure may lower this risk.
  • The study, called ASTOP, is a multicenter, randomized, double-blind trial involving 484 patients, comparing the effects of 200 mg of aspirin versus a placebo prior to treatment.
  • Primary outcomes will focus on measuring thromboembolic complications and ischemic lesions during the procedure, while secondary outcomes will assess cerebral ischemic events, bleeding incidents, and patient functional status after 90 days.
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Article Synopsis
  • The study explored changes in the infrapatellar fat pad (IFP) during walking among 17 healthy young participants, using ultrasonography to measure its thickness in different positions: supine, standing, and walking.
  • Results showed that the IFP was thicker while walking compared to other positions, and its thickness changed dynamically throughout the gait cycle.
  • The findings also indicated a significant correlation between the IFP’s morphological changes during walking and the knee flexion moment (KFM), suggesting that IFP dynamics are linked to knee mechanics.
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Article Synopsis
  • - This study examines how ACL reconstruction affects medial meniscal extrusion (MME) during weight-bearing activities, as abnormal mechanical stress can lead to meniscus issues post-surgery.
  • - Seventeen patients who had unilateral ACL reconstruction and 20 healthy volunteers were evaluated through ultrasonography and MRI before and after the surgery to assess MME and knee function.
  • - Results showed that while MME in resting positions didn’t change significantly, there was an increase in MME during standing and walking after the ACL surgery, indicating altered knee mechanics under stress compared to healthy individuals.
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Article Synopsis
  • The study examines clinical outcomes of two treatment options for distal anterior cerebral artery (DACA) aneurysms: microsurgery and endovascular treatment (EVT).
  • It analyzes data from 166 patients across 16 stroke centers, comparing the efficacy, complications, and recurrence rates of both treatments over a median follow-up of 15.3 months.
  • Findings suggest that while EVT may be a viable alternative to microsurgery, especially for unruptured aneurysms, it shows higher recurrence and retreatment rates, particularly in cases of ruptured aneurysms, highlighting the need for careful monitoring.
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Background: A flatfoot has been believed to be closely associated with the development of hallux valgus; however, the association is still controversial. Abnormal foot kinematics has been identified as a possible risk factor for the development of hallux valgus, but it remains unclear whether foot posture contributes to abnormal foot kinematics. This is the first study to investigate the differences in foot kinematics during gait between individuals with and without hallux valgus, while controlling for foot posture.

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