Front Cell Infect Microbiol
August 2025
Introduction: () causes most cases of the urinary tract infections (UTIs) via virulence factors like biofilms. This study identifies key phenotypic and genotypic virulence attributes of Uropathogenic Escherichia coli.
Methodology: A total of 180 uropathogenic (UPEC) isolated from patients with different categories (cystitis, pyelonephritis, recurrent UTI, catheter-associated UTI, and asymptomatic bacteriuria) of UTI and 30 commensal isolated from healthy individuals were evaluated for biofilm production by phenotypic methods using tissue culture plate, tube adherence, and Congo red method, and RT-PCR was used to genetically characterize them.
This case report highlights the management of recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) in a post-renal transplant patient. Despite the challenges posed by antibiotic resistance, the patient was successfully treated with an extended infusion of meropenem, underscoring the efficacy of this approach in such difficult cases. The patient's recurrent infections required multiple hospitalizations and adjustments in treatment protocols, including the use of alternative antibiotics like fosfomycin and tailored immunosuppressive management to control both infection and rejection.
View Article and Find Full Text PDFIntroduction: Urinary tract infections (UTIs) are common bacterial infections with significant health implications. This study aimed to assess the antimicrobial susceptibility (AST) patterns of isolated from urine samples over a decade (2014-2023).
Methods: The study analyzed isolates AST pattern from urine samples at a tertiary care hospital in Mysuru (Karnataka), South India using the VITEK-2 (bioMérieux, France) database.
Front Med (Lausanne)
March 2025
serovar Weltevreden, a non-typhoidal serovar, has emerged as a significant foodborne pathogen, particularly in Southeast Asian countries. While it is commonly associated with gastroenteritis and foodborne outbreaks, it can also lead to invasive infections in immunocompromised adults and neonates. This case report presents a rare instance of myocarditis associated with Weltevreden gastroenteritis in a 43-year-old healthy male physician from South India.
View Article and Find Full Text PDFThis case report describes a 37-year-old man who underwent renal transplantation and subsequently developed complicated recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) . Despite initial treatment with fosfomycin and meropenem, the patient experienced persistent UTIs, leading to multiple hospitalizations. The management of these recurrent infections eventually required the use of tigecycline.
View Article and Find Full Text PDFThis case report on recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) in a post-renal transplant patient underscores the significant clinical challenge of managing MDR infections in immunocompromised individuals, particularly in the context of renal transplantation. The patient was treated with an extended infusion of meropenem, which offers prolonged drug exposure and enhances bactericidal activity against MDR pathogens. This approach is critical in overcoming the resistance mechanisms inherent to , thereby improving the likelihood of therapeutic success.
View Article and Find Full Text PDFserovar Hvittingfoss, a member of the non-typhoidal group, is an important foodborne serovar most frequently identified in regions (Australia, Belgium, and the United States) with active surveillance systems. This serovar has been implicated in outbreaks of foodborne illness. Soft cheese, crab cocktail, beef, and rock melon are commonly involved in these outbreaks.
View Article and Find Full Text PDFThis case report details the clinical management and implications of infection with pan-drug-resistant in a 50-year-old male admitted and diagnosed with acute peritonitis due to hollow viscus perforation, highlighting an emerging challenge in healthcare settings. Following emergency laparotomy and intensive care admission, the patient was catheterized to assist urine drainage and subsequent urine bacterial culture which yielded pan-drug-resistant , signifying a notable instance of nosocomial infection by a multi-drug-resistant organism. Despite the organism's resistance to broad-spectrum antibiotics, clinical improvement was observed with levofloxacin treatment, underlining the potential discrepancy between in vitro resistance patterns and in vivo response, particularly in urinary tract infections (UTIs) where urine drug concentrations are pivotal.
View Article and Find Full Text PDFCureus
October 2024
Background Diabetic foot ulcers (DFUs) are common complications in diabetes patients, often leading to sepsis and leg amputation. Methicillin-resistant Staphylococcus aureus (MRSA) infections in DFUs pose challenges due to methicillin resistance with and genes. This study aims to assess the prevalence of MRSA in clinical isolates from DFUs, analyze the antibiogram of MRSA isolates, and detect the presence of the and genes among MRSA isolates.
View Article and Find Full Text PDFFront Public Health
August 2024
serovar Newport is a human pathogen underreported in most developing countries. It is known for causing gastroenteritis and extraintestinal infections. In this case report, we report the case of ceftriaxone-resistant serovar Newport from South India, causing acute gastroenteritis in a sixty-year-old female patient having a history of antimicrobial therapy and recent hospital admission.
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