Bevacizumab as a mitigating factor for the impact of high systemic immune-inflammation index on chemorefractory in advanced epithelial ovarian cancer.

Background: Predicting chemorefractory disease in advanced epithelial ovarian cancer (EOC) remains challenging. This study aimed to identify clinicopathological factors and hemogram data as predictive markers for chemorefractory EOC and to explore potential therapeutic approaches that may mitigate these unfavorable conditions.

Methods: We conducted a retrospective analysis of patients with advanced EOC treated with chemotherapy.

Development of polymorphic simple sequence repeat markers in (Lycopodiaceae).

Premise: The natural population size of (Lycopodiaceae) has dramatically decreased and the species has become endangered due to overexploitation. Here, we developed simple sequence repeat (SSR) markers for to survey both its genetic diversity and population structure.

Methods And Results: Based on 177 individuals, 120 SSR primer pairs were developed and optimized from five regions of the transcriptomic data.

Exploring mechanisms of resistance to dimethachlone in Sclerotinia sclerotiorum.

Background: The dicarboximide fungicide dimethachlone has been widely used in China for more than 12 years to control the Sclerotinia stem rot caused by Sclerotinia sclerotiorum disease. First signs of resistance in the field are reported at low frequency. In this study, four resistant isolate/mutants were used to explore still unknown mechanisms leading to dimethachlone resistance.