Associations of ambient air pollution exposure and sleep pattern with brain structures: A prospective study in the UK Biobank.

Background: Previous studies have shown associations between exposure to air pollution (AP) and total gray matter volume (GMV) and total white matter volume (WMV). However, no study has explored the impact of sleep conditions (sleep behaviors and sleep patterns) on the associations between AP and brain structures.

Methods: This study included over 21,000 participants from the UK Biobank.