Exploring the mechanism of Carbonized Typhae Pollen in treating blood stasis syndrome through metabolic profiling: the synergistic effect of hemostasis without blood stasis.

Ethnopharmacological Relevance: Removing blood stasis and stopping bleeding traditional Chinese medicines (RBSB-TCM) formed a unique class of TCM, characterized by vasodilating, removing stasis and hemostatic effects. Carbonized Typhae Pollen (CTP), derived from Typhae Pollen (TP) through carbonization, has emerged as a particularly valuable therapeutic agent. It has been widely used in clinical practice to treat hemorrhagic disorders caused by blood stasis syndrome (BSS).

Chemical composition analysis of the proteins of leech extract with anti-pulmonary fibrosis and their effects on metabolomics based on chromatography-mass spectrometry.

Idiopathic pulmonary fibrosis is a high-mortality chronic lung disease, and currently existing medications have limited therapeutic efficacy with noticeable adverse effects, urgently necessitating the exploration of more effective and safer treatment options. Our preliminary studies have demonstrated that the leech extract group with molecular weight greater than 10 kDa (>10 kDa group) exhibited superior anti-idiopathic pulmonary fibrosis efficacy. To trace the active components of > 10 kDa group, it was separated by gel electrophoresis and analyzed by Nano LC-MS/MS.

Coupled controls of the infiltration of rivers, urban activities and carbonate on trace elements in a karst groundwater system from Guiyang, Southwest China.

Hydrogeochemical processes of trace elements (TEs) are of considerable significance to river water and groundwater resource assessment and utilization in the karst region. Therefore, seven TEs were analyzed to investigate their contents, spatial variations, sources, and controlling factors in Guiyang, a typical karst urban area in southwest China. The results showed that the average content of TEs in river water (e.

The effects of wenxin keli on left ventricular ejection fraction and brain natriuretic Peptide in patients with heart failure: a meta-analysis of randomized controlled trials.

Objective. To evaluate the beneficial and adverse effects of Wenxin Keli (WXKL), either alone or in combination with Western medicine, on the left ventricular ejection fraction (LVEF) and plasma brain natriuretic peptide (BNP) in the treatment of heart failure (HF). Methods.