Publications by authors named "Xiangxi Du"

This work investigated the high-throughput classification performance of microscopic images of mesenchymal stem cells (MSCs) using a hyperspectral imaging-based separable convolutional neural network (CNN) (H-SCNN) model. Human bone marrow mesenchymal stem cells (hBMSCs) were cultured, and microscopic images were acquired using a fully automated microscope. Flow cytometry (FCT) was employed for functional classification.

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Article Synopsis
  • The study investigates the role of programmed death-ligand 1 (PD-L1) in condyloma acuminatum, particularly its interaction with human papillomavirus (HPV) and its potential role in suppressing the immune response.* -
  • Researchers found that PD-L1 is highly expressed in the warts of patients affected by condyloma acuminatum and that HPV can enhance PD-L1 expression in affected cells.* -
  • The HPV-infected cells not only increased PD-L1 levels but also impacted T-cell function by promoting apoptosis and inhibiting proliferation of Jurkat cells, thereby contributing to immunosuppression in that local environment.*
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Background: Human papillomavirus (HPV) infected keratinocyte dysfunction results in the formation of genital warts, and the specific role of Sonic hedgehog (SHh) signaling in genital warts remains elusive. Thus, this study aimed to identify the correlation between wart formation and SHh signaling.

Materials And Methods: In this study, nine male patients with genital warts were recruited, and the expression of SHh and its downstream signal molecules Patched-1 and GLI family zinc finger 1 (Ptch1 and Gli1) was detected.

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This exploration is to solve the efficiency and accuracy of cell recognition in biological experiments. Neural network technology is applied to the research of cell image recognition. The cell image recognition problem is solved by constructing an image recognition algorithm.

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The current work aims to strengthen the research of segmentation, detection, and tracking methods of stem cell image in the fields of regenerative medicine and tissue damage restoration. Firstly, based on the relevant theories of stem cell image segmentation, digital twins (DTs), and lightweight deep learning, a new phase contrast microscope is introduced through the research of optical microscope. Secondly, the results of DTs method and phase contrast imaging principle are compared in stem cell image segmentation and detection.

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The bearing-rotor system is prone to faults during operation, so it is necessary to analyze the dynamic characteristics of the bearing-rotor system to discuss the optimal structure of the convolutional neural network (CNN) in system fault detection and classification. The turbo expander is undertaken as the research object. Firstly, the hybrid magnetic bearing-rotor system is modeled into the form of four stiffness coefficients and four damping coefficients, so as to analyze and explain the dynamic characteristics of the system.

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The hybrid electromagnetic and elastic foil gas bearing is explored based on the radial basis function (RBF) neural network in this study so as to improve its stabilization in work. The related principles and structure of hybrid electromagnetic and elastic foil gas bearings is introduced firstly. Then, the proportional, integral, and derivative (PID) bearing controller is introduced and improved into two controllers: IPD and CPID.

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Although depressive symptoms including anhedonia (i.e., loss of pleasure) frequently accompany pain, little is known about the risk factors contributing to individual differences in pain-induced anhedonia.

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