Publications by authors named "Virgile Zimmermann"
Performance of Different Versions of Duke Criteria in Diagnosing Infective Endocarditis in Patients With Intracardiac Prosthetic Materials.
Open Forum Infect Dis
September 2025
Background: Diagnosing infective endocarditis (IE) is a significant challenge. This study aimed to compare the diagnostic performance of the 2015 and 2023 European Society of Cardiology (ESC) and the 2023 International Society for Cardiovascular Infectious Diseases (ISCVID) Duke clinical criteria in a cohort of patients with suspected IE and intracardiac prosthetic material.
Methods: This retrospective study was conducted at 2 Swiss University Hospitals (2014-2024).
Background: Identifying patients at low risk for infective endocarditis (IE) among those with bacteremia by Gram-positive cocci is critical to optimize cardiac imaging use. The aim was to assess the diagnostic performance of blood culture parameters in identifying patients at low risk for IE.
Methods: Adult patients with bacteremia due to , streptococci, or at the Lausanne University Hospital were included.
Background: Enterococci are a common cause of infective endocarditis (IE). This study aimed to assess the diagnostic performance of the 2015 and 2023 Duke versions of the European Society of Cardiology (ESC) Duke criteria, as well as the 2023 Duke International Society of Cardiovascular Infectious Diseases (ISCVID) clinical criteria, for identifying IE among patients with enterococcal bacteremia.
Methods: We included adult retrospective patients with enterococcal bacteremia from 3 independent cohorts across 2 Swiss university hospitals between 2015 and 2024.
Purpose: To identify predictors of mortality among patients with enterococcal bacteraemia.
Methods: This retrospective study was conducted at the Lausanne University Hospital, Switzerland and included adult patients with enterococcal bacteraemia from 2014 to 2023.
Results: During the study period, 768 enterococcal bacteraemia episodes were included.
Purpose: To ascertain the predictors of persistent bacteraemia among patients with suspected infective endocarditis (IE) and those with IE.
Methods: Retrospective study.
Setting: This study conducted at a Swiss university hospital (2015-2023) included adult patients with bacteraemia and suspected IE.
Purpose: To evaluate the performance of the Duke clinical criteria of the European Society of Cardiology (ESC; 2015 and 2023 versions) and the 2023 International Society for Cardiovascular Infectious Diseases (ISCVID) in diagnosing infective endocarditis (IE) among patients with bacteraemia/candidaemia by pathogens introduced for the first time as typical microorganisms by ISCVID.
Methods: Retrospective study.
Setting: This study included adult patients with bacteraemia/candidaemia by such pathogens (coagulase negative staphylococci, Abiotrophia spp.
Among 3127 episodes of suspected infective endocarditis, the 2023 Duke-International Society for Cardiovascular Infectious Diseases clinical criteria showed an accuracy of 90% for infective endocarditis diagnosis. A new heart murmur was present in 690 (22%) episodes. Excluding imaging and surgical findings decreased the accuracy to 73%, while using the physical examination criterion slightly improved the accuracy to 78%.
View Article and Find Full Text PDFObjectives: Duration of treatment for uncomplicated streptococcal bacteraemia is unknown. The study aims to assess clinical outcomes of patients with uncomplicated streptococcal bacteraemia receiving a short course (5-10 days) of antimicrobial treatment compared to those receiving the traditional, longer duration (11-18 days).
Methods: This retrospective study was conducted at the Lausanne University Hospital, Switzerland and included episodes of uncomplicated streptococcal bacteraemia among adult patients from 2015 to 2023.
Impact of multidisciplinary Endocarditis Team on management of infective endocarditis.
Braz J Infect Dis
October 2024
Infective Endocarditis (IE) is a complex, life-threatening disease. The aim of the present study was to evaluate the impact of the Endocarditis-Team on management of IE. This observational study conducted at a university hospital (2015‒22), included adult patients with IE.
View Article and Find Full Text PDFArticle Synopsis
- Diagnosing infective endocarditis (IE) is complex, and this study compared the effectiveness of the 2015 and 2023 Duke clinical criteria for diagnosing the condition.
- Conducted in two Swiss University Hospitals, researchers analyzed data from 3127 patients suspected of having IE, with 1177 confirmed cases, to assess the agreement between the clinical criteria and expert diagnoses.
- Results showed that the 2023 criteria had a higher sensitivity (69%) compared to the 2015 criteria (59%), although both versions categorized about one-third of episodes as possible IE.
Background: Streptococci are a common cause of infective endocarditis (IE). We aimed to evaluate the performance of the HANDOC score to identify patients at high risk for IE and the Duke clinical criteria of the European Society of Cardiology (ESC; 2015 and 2023 versions) and the 2023 version from the International Society of Cardiovascular Infectious Diseases (ISCVID) in diagnosing IE among patients with streptococcal bacteremia.
Methods: This retrospective study included adult patients with streptococcal bacteremia hospitalized at Lausanne University Hospital.
Background: Streptococcal bacteremia is associated with high mortality. Thia study aims to identify predictors of mortality among patients with streptococcal bacteremia.
Methods: This retrospective study was conducted at the Lausanne University Hospital, Switzerland, and included episodes of streptococcal bacteremia among adult patients from 2015 to 2023.