Publications by authors named "Vincent Parinet"
Long-term outcome after autologous -negative peripheral blood stem cell transplantation in adults with Philadelphia-positive acute lymphoblastic leukemia: a comparative study.
Haematologica
April 2024
Article Synopsis
- HSCT recipients have a high risk of severe COVID-19 and show altered immune responses to vaccinations; this study focused on how well they responded to the BNT162b2 mRNA vaccine.
- A significant number of HSCT recipients were given a third vaccine dose if their antibody levels were low a month after the second dose; six months later, the antibody levels declined but 72% still had protective levels.
- Factors like immunosuppressive treatment and low lymphocyte counts were linked to reduced antibody levels, and a small number of participants experienced COVID-19 infections, with one resulting in death.
Translocation t(4;12)(q11-13;p13) is a recurrent but very rare chromosomal aberration in acute myeloid leukaemia (AML) resulting in the non-constant expression of a CHIC2/ETV6 fusion transcript. We report clinico-biological features, molecular characteristics and outcomes of 21 cases of t(4;12) including 19 AML and two myelodysplastic syndromes (MDS). Median age at the time of t(4;12) was 78 years (range, 56-88).
View Article and Find Full Text PDFEosinophil-rich tissue infiltrates in chronic myelomonocytic leukemia patients.
Leuk Lymphoma
December 2017
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic disorder that associates dysplastic and proliferative features. Tissue inflammatory disorders occur in a fraction of CMML patients during the course of their disease. Here, we describe the occurrence of eosinophil-rich tissue inflammation, including eosinophilic pneumonia, chondritis, and cystitis, in CMML patients.
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