Obstetric and perinatal outcomes in singleton pregnancies following medicated, stimulated and natural, frozen embryo transfer cycles: an updated systematic review and meta-analysis.

Frozen embryo transfer (FET) has been associated with higher risks of hypertensive disorders of pregnancy (HDP), large for gestational age and high birth weight. This systematic review and meta-analysis evaluates obstetric and perinatal outcomes in medicated, stimulated and natural FET cycles. A literature search was performed using MEDLINE, EMBASE, CINAHL and the Cochrane Library database; 152,590 FET cycles were analysed from 31 included studies.

A core outcome set for future male infertility research: development of an international consensus.

Objective: To develop a core outcome set for male infertility trials.

Design: A two-round Delphi survey and consensus development workshop were undertaken with healthcare professionals, researchers and clinicians globally.

Subjects: 334 participants from 39 countries participated in the Delphi Survey, while 44 participants from 21 countries participated in the consensus development workshop.

A core outcome set for future male infertility research: development of an international consensus.

Study Question: Can a core outcome set be developed through a global consensus to standardize outcome selection, collection, comparison, and reporting in future male infertility trials?

Summary Answer: A minimum dataset, known as a 'core outcome set', has been developed for randomized controlled trials (RCTs) and systematic reviews evaluating potential interventions for male infertility.

What Is Known Already: Numerous factors, including a failure to consider the perspectives of men with lived experiences of infertility or their partners when developing and conducting RCTs can limit their clinical utility. Selection of outcomes, variations in outcome definitions, and the selective reporting of outcomes based on statistical analysis make the results of infertility research challenging to interpret, compare, and implement.

Differentiation of placenta-derived MSCs cultured in human platelet lysate: a xenofree supplement.

In the last few decades, mesenchymal stem cells (MSCs)-based regenerative therapies in clinical applications have gradually become a hot topic due to their long-term self-renewal and multilineage differentiation ability. In this scenario, placenta (p) has been considered as a good source of MSCs. As a tissue of fetal origin with abundant number of stem cells compared to other sources, their non-invasive acquisition, strong immunosuppression, and lack of ethical concerns make placenta an indispensable source of MSC in stem cell research and therapy.

Effect of female body mass index on intrauterine insemination outcomes: a systematic review and meta-analysis.

The prevalence of women with a raised body mass index (BMI) seeking assisted conception treatment is increasing. Findings of existing studies evaluating the effect of female BMI on intrauterine insemination (IUI) treatment outcomes remain inconsistent. This systematic review and meta-analysis evaluate the effect of female BMI on IUI treatment outcomes.

Optic flow in the natural habitats of zebrafish supports spatial biases in visual self-motion estimation.

Animals benefit from knowing if and how they are moving. Across the animal kingdom, sensory information in the form of optic flow over the visual field is used to estimate self-motion. However, different species exhibit strong spatial biases in how they use optic flow.

Endometriosis and oocyte quality: an analysis of 13 614 donor oocyte recipient and autologous IVF cycles.

Study Question: Does endometriosis affect live birth following donor oocyte recipient versus autologous IVF?

Summary Answer: There was no significant difference in the live birth rate (LBR) in women with endometriosis undergoing donor oocyte recipient cycles versus autologous IVF cycles.

What Is Known Already: For infertile women with endometriosis, IVF is often considered as a treatment option. Lower implantation and pregnancy rates have been observed following IVF in women with endometriosis.

A systematic review highlighting poor quality of evidence for content validity of quality of life instruments in female chronic pelvic pain.

Objectives: To evaluate the content validity of 19 patient-reported outcome measures (PROMs) used to measure quality of life (QoL) in women with chronic pelvic pain (CPP).

Study Design And Setting: We searched Embase, MEDLINE, PsycINFO databases and Google Scholar from inception to August 2020. We included records describing the development or studies assessing content validity of PROMs.

Outcome reporting across randomized controlled trials evaluating potential treatments for male infertility: a systematic review.

Study Question: What are the primary outcomes and outcome measures used in randomized controlled trials (RCTs) evaluating potential treatments for male infertility in the last 10 years?

Summary Answer: Outcome reporting across male infertility trials is heterogeneous with numerous definitions and measures used to define similar outcomes.

What Is Known Already: No core outcome set for male infertility trials has been developed. Male infertility trials are unique in that they have potentially three participants, a man, a female partner and their offspring and this will likely lead to significant variation in outcome reporting in randomized trials.

Mesenchymal Stem Cell (MSCs) Therapy for Ischemic Heart Disease: A Promising Frontier.

Although tremendous progress has been made in conventional treatment for ischemic heart disease, it still remains a major cause of death and disability. Cell-based therapeutics holds an exciting frontier of research for complete cardiac recuperation. The capacity of diverse stem and progenitor cells to stimulate cardiac renewal has been analysed, with promising results in both pre-clinical and clinical trials.

Draft Genome Sequence of Bacillus pacificus KVCMST-8A-12, Isolated from a Marine Sediment Sample from the Kanyakumari Coast, India.

A DNase-producing Bacillus pacificus strain was isolated, and the whole-genome sequence is reported in this paper. The draft genome sequence of Bacillus pacificus KVCMST-8A-12 constitutes 2.4 Gbp of raw reads, with a GC content of 35.

Evaluation of clinical practice guidelines (CPG) on the management of female chronic pelvic pain (CPP) using the AGREE II instrument.

Introduction And Hypothesis: Variations in guidelines may result in differences in treatments and potentially poorer health-related outcomes. We aimed to systematically review and evaluate the quality of national and international guidelines and create an inventory of CPG recommendations on CPP.

Methods: We searched EMBASE and MEDLINE databases from inception till August 2020 as well as websites of professional organizations and societies.

A meta-synthesis of qualitative literature on female chronic pelvic pain for the development of a core outcome set: a systematic review.

Introduction And Hypothesis: Qualitative research has an increasing role in the development of core outcome sets (COS) adding patient perspectives to the considerations of core outcomes. We aimed to identify priorities of women with experience of chronic pelvic pain (CPP).

Methods: The search strategy was a systematic review of qualitative studies identified from Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL, EMBASE, MEDLINE and PsycInfo databases.

SSIM Compliant Modeling Framework With Denoising and Deblurring Applications.

In image processing, it is well known that mean square error criteria is perceptually inadequate. Consequently, image quality assessment (IQA) has emerged as a new branch to overcome this issue, and this has led to the discovery of one of the most popular perceptual measures, namely, the structural similarity index (SSIM). This measure is mathematically simple, yet powerful enough to express the quality of an image.

The impact of emotional health on assisted reproductive technology outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis has addressed ongoing controversy surrounding the association between pre-treatment anxiety, stress and depression and assisted reproductive technology (ART) outcomes. Medline, Embase and PsycINFO were searched up to November 2019. The eligibility criterion was observational studies reporting the association between pre-treatment anxiety, stress or depression and ART outcomes in men, women or couples undergoing ART.

Visual Saliency Detection Using Spatiotemporal Decomposition.

We propose a novel technique for detection of visual saliency in dynamic video based on video decomposition. The decomposition obtains the sparse features in a particular orientation by exploiting the spatiotemporal discontinuities present in a video cube. A weighted sum of the sparse features along three orthogonal directions determines the salient regions in the video cubes.

Automatic Facial Expression Recognition System Using Deep Network-Based Data Fusion.

This paper presents a novel automatic facial expressions recognition system (AFERS) using the deep network framework. The proposed AFERS consists of four steps: 1) geometric features extraction; 2) regional local binary pattern (LBP) features extraction; 3) fusion of both the features using autoencoders; and 4) classification using Kohonen self-organizing map (SOM)-based classifier. This paper makes three distinct contributions.

Surgical options for the retrieval of a migrated intrauterine contraceptive device.

The intrauterine contraceptive device is a popular form of contraception for women; however, it does carry a rare but serious risk of migration into the myometrium and then into the peritoneal cavity. We report an unusual case of an intrauterine contraceptive device (IUCD) migrating through the uterus into the peritoneal cavity and subsequently into the sigmoid colon, which was finally retrieved laparoscopically. We also discuss three different methods for the retrieval of a migrated IUCD: colonoscopy, hysteroscopy and laparoscopy and compare and contrast each method.