Publications by authors named "Vendidandala Nagarjuna Reddy"
Gallocatechin-silver nanoparticles embedded in cotton gauze patches accelerated wound healing in diabetic rats by promoting proliferation and inhibiting apoptosis through the Wnt/β-catenin signaling pathway.
Vendidandala Nagarjuna Reddy
,
Shaik Nyamathulla
,
Khomaizon Abdul Kadir Pahirulzaman
,
Seri Intan Mokhtar
,
Nelli Giribabu
PLoS One
June 2022
Article Synopsis
- Diabetes mellitus is a chronic condition that leads to high blood sugar and can result in slow wound healing, presenting significant health challenges.
- This research examines the effectiveness of gallocatechin (GC) and silver nanoparticles (AgNPs) in wound healing for diabetic rats, finding that certain patches significantly improved healing rates.
- Molecular analysis showed that these treatments increased levels of proliferation markers and reduced apoptosis markers, suggesting they enhance wound healing by modulating critical biological pathways.
Gallocatechin‑silver nanoparticle impregnated cotton gauze patches enhance wound healing in diabetic rats by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Nagarjuna Reddy Vendidandala
,
Tan Pei Yin
,
Giribabu Nelli
,
Visweswara Rao Pasupuleti
,
Shaik Nyamathulla
Life Sci
December 2021
This study is designed to investigate the combination of gallocatechin (GC) and silver nanoparticles (AgNPs) for its wound healing ability in diabetic rats. Thirty male Sprague Dawley rats were randomly divided into 5 groups: 1. Normal control rats dressed with blank CGP1; 2.
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