Background: Overweight/obesity has increased to an epidemic proportion throughout the globe and is an important risk factor for many non-communicable diseases. Globally, 2.5 billion people were overweight/obese and 890 million were obese in 2022.
View Article and Find Full Text PDFIntroduction: Septic shock is one of the most common causes of neonatal mortality. Dopamine and epinephrine are the two main drugs used in fluid refractory neonatal septic shock. However, there is lack of consensus on use of first line agent in neonates.
View Article and Find Full Text PDFObjectives: The primary objective was to determine the area under the curve of optic nerve sheath diameter >4.5 mm for detection of raised intracranial pressure in children aged 1 year to 12 years admitted to PICU with neurological signs and symptoms. Our secondary objectives were to compare optic nerve sheath values in study population with age and sex-matched controls and determine change after 30 minutes of osmotherapy.
View Article and Find Full Text PDF, a member of the complex (MTBC), has emerged as a significant contributor to tuberculosis (TB) in cattle, wildlife, and humans. However, understanding about its pathogenesis and severity is limited, compounded by the lack of reliable TB biomarkers in cattle. This study delves into the comparative pathology and transcriptomic landscape of pulmonary granulomas in cattle naturally infected with , using high-throughput RNA sequencing.
View Article and Find Full Text PDFObjectives: To determine the area under curve (AUC) for vasoactive ventilation renal score (VVRS) > 10 at 24-h of admission for predicting mortality in children aged 1-12 years admitted to pediatric intensive care unit (PICU). To also determine the AUC for VVRS > 10 at 48-h of admission for predicting mortality and to determine the AUC of VVRS > 10 at 24-h and 48-h of admission for predicting PICU stay > 3 days, hospital stay > 10 days and mechanical ventilation > 3 days.
Methods: This observational study included 310 children aged 1-12 years admitted in PICU.