Assessing the effect of gastrointestinal conditions and solubility on the bioaccessibility of polyphenolic compounds from a white grape marc extract.

This study investigates the bioaccessibility of phenolic compounds from a Vitis vinifera marc extract using an in vitro gastrointestinal model. Both undiluted and five-fold diluted extracts were digested to assess how solubility and gastrointestinal conditions impact polyphenol bioaccessibility. The extract was obtained using the environmentally friendly Medium Scale Ambient Temperature (MSAT) system.

Citizen Science to Raise Antimicrobial Resistance Awareness in the Community: The MicroMundo Project in Spain and Portugal.

Antimicrobial resistance (AMR) poses a global threat to human, animal and environmental health. Among the multidisciplinary tasks aimed at collectively tackling the AMR crisis, surveillance, research and education stand as major priorities. Based on a crowdsourcing research strategy, the MicroMundo project, a partner of the Tiny Earth initiative in Spain and Portugal, has been developed and consolidated with success in the academic environment.

Study of the Antibacterial Activity of Rich Polyphenolic Extracts Obtained from against Foodborne Pathogens.

Natural extracts containing high polyphenolic concentrations may act as good antimicrobials for their antibacterial and antibiofilm activity. The present research characterizes two hydro-organic extracts with high polyphenolic content, obtained from the shrub as antipathogenic candidates. As a result of their own composition, both extracts, LE050 and PG050, have shown pronounced bioactivities with potential uses, especially in agricultural, livestock production, food manufacturing, and pharmaceutical industries.

Antimicrobial Activity of Polyphenols and Natural Polyphenolic Extracts on Clinical Isolates.

Antibiotic resistance is a growing global problem that affects people, animals, the environment, and the economy. Many clinically relevant bacteria have become resistant to antibiotics, and this fact is emerging as one of the major threats to public health. The lack of new antibiotics, which is due to their time-consuming and costly development, exacerbates the problem.

A Hundred Years of Bacteriophages: Can Phages Replace Antibiotics in Agriculture and Aquaculture?

Agriculture, together with aquaculture, supplies most of the foodstuffs required by the world human population to survive. Hence, bacterial diseases affecting either agricultural crops, fish, or shellfish not only cause large economic losses to producers but can even create food shortages, resulting in malnutrition, or even famine, in vulnerable populations. Years of antibiotic use in the prevention and the treatment of these infections have greatly contributed to the emergence and the proliferation of multidrug-resistant bacteria.

Bacteriophages and Lysins as Possible Alternatives to Treat Antibiotic-Resistant Urinary Tract Infections.

Urinary tract infections represent a major public health problem as the rapid emergence of antibiotic-resistant strains among uropathogens is causing the failure of many current treatments. The use of bacteriophages (phages) and their derivatives to combat infectious diseases is an old approach that has been forgotten by the West for a long time, mostly due to the discovery and great success of antibiotics. In the present so-called "post-antibiotic era", many researchers are turning their attention to the re-discovered phage therapy, as an effective alternative to antibiotics.

Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases.

Natural extracts containing high polyphenolic concentration possess antibacterial, anti-parasitic and fungicidal activities. The present research characterises two extracts based on white grape marc, a winemaking by-product, describing their physicochemical features and antimicrobial capacities. The main components of these extracts are phenolic acids, flavan-3-ols and their gallates and flavonols and their glycosides.

Polyphenolic content and bioactivities of L. (Rosaceae).

Solid-Liquid Extraction (SLE) using solvent of different polarities (CHCl, EtOAc, and -BuOH) has been applied to leaves and fruits from ( L.), a deciduous shrub with an expected rich phytochemical profile. The total polyphenols content and the radical scavenging activity of each extract were evaluated.

Fabrication of Zn-Sr-doped laser-spinning glass nanofibers with antibacterial properties.

The morphology and dimensions of bioactive materials are essential attributes to promote tissue culture. Bioactive materials with nanofibrous structure have excellent potential to be used as bone-defect fillers, since they mimic the collagen in the extracellular matrix. On the other hand, bioactive glasses with applications in regenerative medicine may present antibacterial properties, which depend on glass composition, concentration and the microorganisms tested.

Recent patents on microbial proteases for the dairy industry.

This paper reviews the general characteristics of exo and endopeptidases of microbial origin currently used in the milk industry. It also includes recent patents developed either to potentiate the enzymatic activity or to improve the resulting milk derivatives. The main application of these proteases is in the cheese-making industry.

Paenibacillus favisporus sp. nov., a xylanolytic bacterium isolated from cow faeces.

During a search for xylan-degrading micro-organisms, a sporulated bacterium was recovered from recent and old cow dung and rectal samples. The isolates were identified as members of a novel species of the genus Paenibacillus, based on 16S rRNA gene sequences. According to the results of phylogenetic analysis, the most closely related species was Paenibacillus azoreducens.