Predicting early hematoma enlargement in spontaneous intracerebral hemorrhage: Hypocalcemia, Hyperglycemia, and CT signs.

Background: Spontaneous intracerebral hemorrhage (sICH) is a severe, stroke subtype, and early hematoma enlargement (HE) strongly predicts mortality and disability. This study aimed to investigate the predictive value of hypocalcemia, hyperglycemia, and computed tomography (CT) imaging signs for early HE in sICH.

Methods: A total of 238 sICH patients admitted to the First People's Hospital Affiliated to Shanghai Jiao Tong University from November 2021 to November 2024 were retrospectively included.

Monitoring the therapeutic efficacy of CA4P in the rabbit VX2 liver tumor using dynamic contrast-enhanced MRI.

Purpose: The present work aims to evaluate whether dynamic contrast-enhanced magnetic resonance Imaging (DCE-MRI) can monitor non-invasively the blocking effect on microvessels of the Combretastatin-A4-phosphate (CA4P) and assess the therapeutic efficacy.

Methods: Forty rabbits were implanted the VX2 tumors specimens. Two weeks later, serial MRI (T1 weighted image, T2 weighted image and DCE) were performed at 0 h, 4 h, 24 h, 3 d and 7 d after CA4P (10 mg/kg) or saline treatment.