Publications by authors named "Thanh D Le"

Purpose: To compare the safety and efficacy of simultaneous portal and hepatic vein embolization (PHVE) versus portal vein embolization (PVE) in enhancing future liver remnant (FLR) hypertrophy in patients with hepatocellular carcinoma (HCC).

Materials And Methods: This retrospective study included 97 patients with HCC who underwent transarterial chemoembolization (TACE) followed by PVE (n = 34) or PHVE (n = 63) for preoperative liver augmentation. Volumetric analysis using contrast-enhanced CT was performed at a median of 25 days (PHVE) and 31 days (PVE) post-embolization (P = .

View Article and Find Full Text PDF

Objective: To evaluate the clinical and technical success of splenic artery embolization (SAE) in the management of splenic trauma and factors affecting treatment outcomes.

Materials And Methods: A retrospective and prospective study was conducted at two centers from December 2019 to December 2023, including 400 patients with splenic trauma (grade III-V according to the American Association for the Surgery of Trauma (AAST) - 2018 classification) and the Abbreviated Injury Scale (AIS) 2005 change from the AIS-1998. Factors affecting the effectiveness of embolization were determined by logistic regression analysis with p < 0.

View Article and Find Full Text PDF

Despite advances in medical care, older patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) currently face high in-hospital mortality rates. Traditional prognostic models, primarily developed in Caucasian populations with fewer older participants and using classical statistical approaches, may not perform well in Southeast Asian settings. This study explores the need for artificial intelligence-based risk assessment models-the STEMI-OP algorithms-designed explicitly for STEMI patients aged 60 and older following primary PCI in Vietnam.

View Article and Find Full Text PDF

Cartilage tissue regeneration remains challenging due to the tissue's poor self-healing capacity, attributed to its hypocellular and avascular nature, which limits nutrient delivery to the defect site and complicates healing. Traditional methods often utilize the subchondral tissue layer to improve nutrient exchange through its vascular network, although these approaches have limitations. To address these issues, 3-dimensional (3D) printing has been employed to create the bilayered scaffold that mimics the complex structure of osteochondral tissue.

View Article and Find Full Text PDF

This paper presents the molecular design of a rose-bengal-containing functional polymer for the encapsulation of carbon nanohorns (CNHs). The polymer chain consists of hydrophilic monomers and dangling oxirane moieties that tether the rose bengal units. It exhibits high biocompatibility with CNHs and excellent coating ability, resulting in a carbon-based nanoconjugate with a core-shell nanostructure.

View Article and Find Full Text PDF

Nuclear medicine imaging (NMI) is essential for the diagnosis and sensing of various diseases; however, challenges persist regarding image quality and accessibility during NMI-based treatment. This paper reviews the use of deep learning methods for generating synthetic nuclear medicine images, aimed at improving the interpretability and utility of nuclear medicine protocols. We discuss advanced image generation algorithms designed to recover details from low-dose scans, uncover information hidden by specific radiopharmaceutical properties, and enhance the sensing of physiological processes.

View Article and Find Full Text PDF

Polarization-sensitive optical coherence tomography (PS-OCT) measures the polarization state of backscattered light from tissues and provides valuable insights into the birefringence properties of biological tissues. Contrastive unpaired translation (CUT) was used in this study to generate a synthetic PS-OCT image from a single OCT image. The challenges related to extensive data requirements relying on labeled datasets using only pixel-wise correlations that make it difficult to efficiently regenerate the periodic patterns observed in PS-OCT images were addressed.

View Article and Find Full Text PDF
Article Synopsis
  • Prussian White (PW) is a promising cathode material for sodium-ion batteries with high capacity and voltage, but its performance varies due to challenges in controlling hydration levels.
  • This study focuses on understanding the dehydration and rapid rehydration processes of PW materials, which are critical for accurate characterization.
  • Findings reveal that drying conditions significantly affect PW's properties and that samples quickly reabsorb moisture from the air, underscoring the importance of maintaining airtight conditions during experimentation.
View Article and Find Full Text PDF

Pancreatic duct adenocarcinoma (PDAC) accounts for about 85-90% of all solid pancreatic tumors, which is well-known for poor prognosis and high morbidity. Despite the massive advent of chemotherapy and radiotherapy in recent years, surgical removal is still considered the cornerstone management option in this situation. Pancreaticoduodenectomy or Whipple procedure is generally contraindicated in metastasis or tumors that encase more than 50% of vessels.

View Article and Find Full Text PDF
Article Synopsis
  • * This hydrogel also includes biphasic calcium phosphate and ascorbic acid to improve its effectiveness in promoting bone repair, and its properties were assessed through various scientific tests.
  • * Findings indicated that the optimal hydrogel formulation, featuring a specific ratio of its components, showed positive potential for bone regeneration without exhibiting toxic effects on cells.
View Article and Find Full Text PDF

Hydrogels have emerged as potential materials for bone grafting, thanks to their biocompatibility, biodegradation, and flexibility in filling irregular bone defects. In this study, we fabricated a novel NAH hydrogel system, composed of N,O-carboxymethyl chitosan (NOCC), aldehyde hyaluronic acid (AHA), and hydroxyapatite (HAp). To improve the mechanical strength of the fabricated hydrogel, a porous polycaprolactone (PCL) matrix was synthesized and used as a three-dimensional (3D) support template for NAH hydrogel loading, forming a novel PCL/NAH hybrid scaffold.

View Article and Find Full Text PDF

Introduction: Older patients typically face elevated mortality rates and greater medical resource utilization during hospitalizations compared to their younger counterparts. Sarcopenia, serving as a prognostic indicator, is related to disability, diminished quality of life, and increased mortality. The SARC-F questionnaire, known for its cost-effectiveness, offers a valuable means of assessing sarcopenia.

View Article and Find Full Text PDF

Organized chronic subdural hematoma is a rare form of chronic subdural hematoma. The optimal treatment method is still controversial. Preoperative middle meningeal artery embolization and craniotomy are effective methods for chronic subdural hematoma.

View Article and Find Full Text PDF

Improving the catalytic activity and durability of platinum-based alloy catalysts remains a formidable challenge in the context of renewable energy electrolysis applications. Herein, a facile and rapid photochemical deposition strategy for the synthesis of gold single atoms (Au SAs) anchored on N-doped carbon is presented. These Au SAs serve as a charge redistribution support for Pt-Ni alloy nanoparticles (PtNi/Au-NDC), creating an extended electron-donating interface with Pt-Ni alloy sites.

View Article and Find Full Text PDF

In this study, we developed an endoscopic hyperspectral imaging (eHSI) system and evaluated its performance in analyzing tissues within tissue phantoms and orthotopic mouse pancreatic tumor models. Our custom-built eHSI system incorporated a liquid crystal tunable filter. To assess its tissue discrimination capabilities, we acquired images of tissue phantoms, distinguishing between fat and muscle regions.

View Article and Find Full Text PDF

The present retrospective study aimed to investigate the diagnostic capacity of and design a diagnostic algorithm for dynamic susceptibility contrast-enhanced MRI (DSCE-MRI) and proton magnetic resonance spectroscopy (H-MRS) in grading low-grade glioma (LGG) and high-grade glioma (HGG). This retrospective study enrolled 57 patients, of which 14 had LGG and 43 had HGG, five had World Health Organization grade 1, nine had grade 2, 20 had grade 3 and 23 had grade 4 glioma. All subjects underwent a standard 3T MRI brain tumor protocol with conventional MRI (cMRI) and advanced techniques, including DSCE-MRI and H-MRS.

View Article and Find Full Text PDF
Article Synopsis
  • Acoustic-resolution photoacoustic microscopy (AR-PAM) provides deep visualization of biological tissues with good contrast, but its resolution and sensitivity are typically lower than that of optical-resolution PAM (OR-PAM).
  • A new computational method using two generative adversarial networks (GANs) has been developed to enhance the resolution and sensitivity of AR-PAM images while maintaining their depth imaging capabilities.
  • Testing on both phantom models and live mouse ear tissues showed that these GANs effectively improved image quality even without exact reference data for deep tissues.
View Article and Find Full Text PDF

Background: The coronavirus disease (COVID-19) pandemic has caused a serious global communicable disease burden. Although COVID-19 and its policy responses have significantly influenced older adults, the impact of COVID-19 on depression in the older population is not fully understood. We aimed to investigate whether a history of COVID-19 infection and a decline in outdoor activities during the COVID-19 pandemic were associated with depression among older adults in Vietnam.

View Article and Find Full Text PDF

Purpose: This study was conducted to evaluate the results of conservative management of blunt splenic trauma according to the American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) in 2018 by embolization.

Methods: This observational study included 50 patients (42 men and 8 women) with splenic injury who underwent multidetector computed tomography (MDCT) and embolization.

Results: According to the 2018 AAST-OIS, 27 cases had higher grades than they did according to the 1994 AAST-OIS.

View Article and Find Full Text PDF

Objective: To determine the rate of positive culture sputum and related factors as well as the microorganism features and antibiotic susceptibility of pathogens in elderly inpatients with exacerbation of chronic obstructive pulmonary disease (COPD) in Thong Nhat Hospital, Vietnam.

Methods: This cross-sectional study included elderly patients admitted to the hospital because of exacerbation of COPD. Data of their medical history, symptoms and signs were collected, and the patients were instructed to collect sputum sample.

View Article and Find Full Text PDF

A synergistic multilayer membrane design is necessary to satisfy a multitude of requirements of an ideal wound dressing. In this study, trilayer dressings with asymmetric wettability, composed of electrospun polycaprolactone (PCL) base membranes coated with oligomer chitosan (COS) in various concentrations of polyvinylpyrrolidone (PVP), are fabricated for wound dressing application. The membranes are expected to synergize the hygroscopic, antibacterial, hemostatic, and biocompatible properties of PCL and COS.

View Article and Find Full Text PDF

Photoacoustic microscopy has received great attention due to the benefits of the optical resolution contrast as well as its superior spatial resolution and relatively deep depth. Like other imaging modalities, photoacoustic images suffer from noise, and filtering techniques are required to remove them. To overcome the noise, we proposed a combination of filters, including an adaptive median filter, an effective filter for impulsive noise, and a nonlocal means filter, an effective filter for background noise, for noise removal and image quality enhancement.

View Article and Find Full Text PDF

This study investigated the effects of dietary supplementation with anthocyanin extracted from black rice bran (AR) on the growth rate, immunological response, and expression of immune and antioxidant genes in Nile tilapia raised in an indoor biofloc system. A total of 300 Nile tilapia fingerlings (15.14 ± 0.

View Article and Find Full Text PDF

Objectives: We investigated the characteristics of prophylactic antimicrobial use in clean and clean-contaminated surgical procedures and assessed the efficacy of a prophylactic antimicrobial stewardship intervention at Thong Nhat Hospital, Ho Chi Minh City, Vietnam.

Methods: A cross-sectional study was conducted on 354 patients who underwent either clean or clean-contaminated surgical procedures at Thong Nhat Hospital. Eligible patients were classified with respect to three periods of intervention from 2017 to 2020.

View Article and Find Full Text PDF

African swine fever (ASF) is a devastating viral disease in pigs and is therefore economically important for the swine industry. ASF is characterized by a short incubation period and immediate death, making the early identification of ASF-infected pigs essential. This pilot-scale study evaluates whether the infrared thermography (IRT) technique can be used as a diagnostic tool to detect changes in skin temperature () during the early stages of disease development in experimentally ASF-infected pigs.

View Article and Find Full Text PDF