Publications by authors named "Tadamichi Mitsuma"

Background: Acupuncture is known to improve exercise capacity in patients with chronic obstructive pulmonary disease (COPD), but its mechanism remains unknown. Whether acupuncture improves exercise capacity in patients with COPD through alleviation of leg fatigue and dyspnea is examined by applying causal mediation analysis to previous trial data.

Methods: Sixty-two patients with COPD completed treatments with either real or placebo acupuncture once a week for 12 weeks.

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  • Drug-induced pseudoaldosteronism can occur as an adverse effect of Kampo formulas, with a study analyzing reports from the Japanese Adverse Drug Event Report database showing specific risk factors.
  • The research identified 210 reports of pseudoaldosteronism among 6334 adverse event reports related to Kampo formulas, with a high prevalence in older females.
  • Key associated factors included older age, female sex, low body weight, diuretic use, hypertension, and dementia, along with the dosage and duration of Glycyrrhiza, which is often included in these formulas.
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  • Acupuncture has been shown to help alleviate symptoms in patients with hematological malignancies, but its safety, especially regarding bleeding risks, hasn't been clearly established.
  • A study at a Japanese medical center analyzed the bleeding risk from acupuncture in patients with low platelet counts (thrombocytopenia) by reviewing medical records and categorizing patients based on their platelet levels.
  • Out of 2423 acupuncture sessions, 815 were analyzed, and the results showed no significant bleeding events in any of the platelet count groups, suggesting that acupuncture is safe for these patients.
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Objective: There are few studies on the relationship between the frequency of acupuncture use and subjective health status. Therefore, we investigated this relationship using data of a previously performed cross-sectional survey of patients visiting Japanese acupuncture clinics.

Methods: This study used data from a cross-sectional survey conducted in 2011 on patients visiting 180 acupuncture clinics nationwide that were run by members of the alumni association of Meiji University of Integrative Medicine Faculty of Acupuncture and Moxibustion, and did not provide treatment other than acupuncture.

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Objective Patients in whom coronavirus disease 2019 (COVID-19) was suspected or confirmed between January 1, 2020, and October 31, 2021, were enrolled from Japanese hospitals in this multicenter, retrospective, observational study. Methods Data on the treatment administered (including conventional and Kampo medicine) and changes in common cold-like symptoms (such as fever, cough, sputum, dyspnea, fatigue, and diarrhea) were collected from their medical records. The primary outcome was the number of days without a fever (with a body temperature <37°C).

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  • Kampo medicine uses a diagnostic method called Fukushin, where doctors apply pressure to the abdomen to assess a patient's health and recommend herbal treatments.
  • A team has developed a Fukushin simulator to teach students and practitioners about different abdominal patterns, and this study builds on that by creating 13 new models that correspond with common Kampo herbal formulas.
  • The new standardized models are expected to enhance the training and accuracy of abdominal diagnosis and prescriptions in Kampo medicine, benefiting both education and practice.
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Background: The number of people with obesity is rapidly increasing worldwide. Since obesity is a critical risk factor for cardiovascular diseases and mortality, the management of obesity is an urgent issue. However, anti-obesity drugs are insufficient in current clinical settings.

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Background: The purpose of this study was to develop an objective, content-valid, and reliable assessment method for Kampo medicine using an objective structured clinical examination (OSCE) for the assessment of clinical competence in Kampo medicine.

Methods: We developed a blueprint followed by a list of 47 assessment items and three task scenarios related to clinical competence in Kampo medicine. An eight-member test committee checked the relevance of the assessment items on a Likert scale.

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While the number of pulmonary tuberculosis cases has decreased, increase in non-tuberculous mycobacterium pulmonary disease (NTM-PD) is a global problem. Guideline-based therapy for NTM-PD sometimes causes complications that prevent treatment completion, and there are many cases of relapse even if the treatment can be completed. In addition to antibacterial treatment, care of host risk factors, such as aging, lean physique and immunosuppressive state, is also very important for the management of NTM-PD.

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Assisted reproductive technology (ART) is an effective treatment developed for infertile couples in the world. As a result, women suffering from infertility benefit from ART treatment. However, even when ART treatment is successfully performed, there are cases where conception is not achieved or maintained.

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A prospective study was conducted in patients with early-stage gastric cancer to determine the efficacy and safety of acupuncture stimulation as an antispasmodic compared with conventional medication during the procedure of endoscopic submucosal dissection (ESD) of the upper gastrointestinal tract. This study was a prospective single blinded quasi-randomized controlled trial. Seventy-three patients who were scheduled to undergo ESD for gastric cancer at Aizu Medical Center between 19 February 2016 and 30 June 2016 were assessed for eligibility for the study.

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Background: There are an increasing number of evidences that chronic obstructive pulmonary disease (COPD) is a systemic illness and that bodyweight loss is its prominent manifestation. We focused on the nutritional outcomes to find out the effectiveness of acupuncture on nutritional state of COPD patients and on their prognosis in our previous interventional study.

Methods: The present study is re-analysis of our previous interventional study, COPD Acupuncture Trial (CAT) published in 2012.

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A woman started to feel intractable pain on her lower legs when she was 76. At the age of 78, she was diagnosed as having Parkinson's disease (PD). The leg pain was suspected to be a symptom of PD after eliminating other causes.

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A 72-year-old male was referred to our hospital in August 2001 for his pulmonary M. fortuitum infection. His symptoms were coughing, pyrexia, hemoptysis, general malaise, and insomnia.

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The purpose of this study was to determine if the adverse effects of interferon (IFN) in hepatitis C patients could be reduced by treatment with Japanese Oriental (Kampo) medicine. Twelve patients with chronic hepatitis C were treated with a combination of IFN-beta and either Mao-to or Dai-seiryu-to (groups A and B), and 16 patients were treated with IFN-beta alone (group C). Mao-to was administered to eight patients and Dai-seiryu-to was administered to four in groups A and B, respectively.

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