Publications by authors named "Shuji Yakubo"

Article Synopsis
  • Kampo medicine uses a diagnostic method called Fukushin, where doctors apply pressure to the abdomen to assess a patient's health and recommend herbal treatments.
  • A team has developed a Fukushin simulator to teach students and practitioners about different abdominal patterns, and this study builds on that by creating 13 new models that correspond with common Kampo herbal formulas.
  • The new standardized models are expected to enhance the training and accuracy of abdominal diagnosis and prescriptions in Kampo medicine, benefiting both education and practice.
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Endothelial progenitor cells (EPCs) are known to repair vascular injuries. Recent studies suggest that Saiko-ka-ryukotsu-borei-To (SKRBT), a traditional herbal medicine that has been used to treat stress-related neuropsychiatric disorders, has protective effects on cardiovascular diseases such as hypertension and arteriosclerosis. Spontaneously hypertensive rats (SHRs) were fed diets containing lyophilized SKRBT extract for 6 weeks.

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Sairei-to (TJ114), a 12-component Japanese herbal medicine, is used to treat immune-related diseases. We investigated the effects of oral administration of TJ114 in a murine model of cardiac transplantation with fully mismatched allografts. Untreated CBA mice rejected C57BL/6 hearts acutely (median survival time [MST], 7 days), whereas survival of allografts from mice given TJ114 was significantly prolonged (MST >100 days).

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