A Comparative Study of Risk Factors across Young and Old Acute Ischemic Strokes: A Hospital-based Study in North India.

Background: Stroke is an important cause of death and disability. Prevalence of stroke differs with age. The risk factors in young differ in comparison to the old age-group.

Tomato HAIRY MERISTEM4, expressed in the phloem, is required for proper shoot and fruit development.

The HAIRY MERISTEM (HAM) gene family encodes Type I and II GRAS domain transcriptional regulators in plants. Type II HAMs, predominantly expressed in meristems and regulated by microRNA171, are essential for maintaining undifferentiated meristems, a role conserved across various species. Conversely, the functions of Type I HAMs have been less characterized.

Unveiling the potential of Aspergillus terreus SJP02 for zinc remediation and its driving mechanism.

In present study, 15 morphologically different fungi isolated from rhizopheric soils of an industrial area were screened for their Zn removal efficiency from aqueous solution. Isolate depicting highest potential was molecularly identified as Aspergillus terreus SJP02. Effect of various process parameters viz.

Industrial scale-up of flue gas bio-mitigation with chemolithotrophs in packed bed reactors: Exploring metabolite synthesis, mass transfer, and techno-economic analysis.

Elevated emissions of flue gases deteriorate the quality of air, impacting both terrestrial and aquatic ecosystems through their contribution to acid rain and eutrophication. This study examines the bio-mitigation process in a packed bed reactor and its capacity to concurrently decrease the environmental consequences of industrial flue gases (CO, NO, and SO) and wastewater by employing mixed bacterial consortia. The highest biomass productivity achieved during the growth phase was 0.

A tomato ethylene-resistant mutant displays altered growth and higher β-carotene levels in fruit.

The mutants resistant to ethylene are helpful in deciphering the role of ethylene in plant development. We isolated an ethylene-resistant tomato (Solanum lycopersicum) mutant by screening for acetylene-resistant (atr-1) seedlings. The atr-1 mutant displayed resistance to kinetin, suggesting attenuation of the ethylene sensing response.

Exploring genetic diversity, population structure, and subgenome differences in the allopolyploid : implications for future breeding and research studies.

Camelina (), an allohexaploid species, is an emerging aviation biofuel crop that has been the focus of resurgent interest in recent decades. To guide future breeding and crop improvement efforts, the community requires a deeper comprehension of subgenome dominance, often noted in allopolyploid species, "alongside an understanding of the genetic diversity" and population structure of material present within breeding programs. We conducted population genetic analyses of a diversity panel, leveraging a new genome, to estimate nucleotide diversity and population structure, and analyzed for patterns of subgenome expression dominance among different organs.

Transpulmonary Pressure-Guided Mechanical Ventilation in Severe Acute Respiratory Distress Syndrome in the PICU: Single-Center Retrospective Study in North India, 2018-2021.

Objectives: In this study, we have reviewed the association between esophageal pressure-guided positive end-expiratory pressure (PEEP) setting and oxygenation and lung mechanics with a conventional mechanical ventilation (MV) strategy in patient with moderate to severe pediatric acute respiratory distress syndrome (PARDS).

Design: Retrospective cohort, 2018-2021.

Setting: Tertiary PICU.

Miniaturized Fab' imaging probe derived from a clinical antibody: Characterization and imaging in CRISPRi-attenuated mammary tumor models.

Clinical imaging-assisted oncosurgical navigation requires cancer-specific miniaturized optical imaging probes. We report a near-infrared (NIR) Fab'-based epidermal growth factor receptor (EGFR)-specific probe carrying 3 NIR fluorophores (Fab'-800CW), which retained high-affinity binding to EGFR ectodomain (equilibrium K  = 1 nM). Fab'-800CW showed a robust 4-times gain of fluorescence intensity (FI) and a 20% lifetime (FLT) increase under the conditions mimicking intracellular degradation.

Sustainable synergistic approach to chemolithotrophs-supported bioremediation of wastewater and flue gas.

Flue gas emissions are the waste gases produced during the combustion of fuel in industrial processes, which are released into the atmosphere. These identical processes also produce a significant amount of wastewater that is released into the environment. The current investigation aims to assess the viability of simultaneously mitigating flue gas emissions and remediating wastewater in a bubble column bioreactor utilizing bacterial consortia.

Fulminant Orbital Cellulitis - A Rare Presentation of Endogenous Endophthalmitis.

Background: Endogenous endophthalmitis refers to the intraocular infection resulting via haematogenous spread from the distant foci. Dengue is an important health problem in India with varied ophthalmic manifestations either due to viremia, immunologic phenomenon, or haemorrhagic tendency.

Case: We report an unusual presentation of endogenous endophthalmitis as fulminant orbital cellulitis in a young adult patient having a history of dengue fever.

Non-derivatizing solvent assisted waste-derived cellulose/ MOF composite porous matrix for efficient metal ion removal: comprehensive analysis of batch and continuous packed-bed column sorption studies.

The use of metal-organic frameworks (MOFs) for wastewater treatment in continuous operation is a major challenge. To address this, the present study demonstrates the eco-friendly and economic synthesis of Ca-MOF immobilized cellulose beads (Ca-MOF-CB) derived from paper waste. The synthesized Ca-MOF-CB were characterized using standard analytical techniques.

A comprehensive review of flue gas bio-mitigation: chemolithotrophic interactions with flue gas in bio-reactors as a sustainable possibility for technological advancements.

Flue gas mitigation technologies aim to reduce the environmental impact of flue gas emissions, particularly from industrial processes and power plants. One approach to mitigate flue gas emissions involves bio-mitigation, which utilizes microorganisms to convert harmful gases into less harmful or inert substances. The review thus explores the bio-mitigation efficiency of chemolithotrophic interactions with flue gas and their potential application in bio-reactors.

Valorization of waste engine oil to mono- and di-rhamnolipid in a sustainable approach to circular bioeconomy.

This study aims to valorize waste engine oil (WEO) for synthesizing economically viable biosurfactants (rhamnolipids) to strengthen the circular bioeconomy concept. It specifically focuses on investigating the influence of key bioprocess parameters, viz. agitation and aeration rates, on enhancing rhamnolipid yield in a fed-batch fermentation mode.

Reforming CO bio-mitigation utilizing Bacillus cereus from hypersaline realms in pilot-scale bubble column bioreactor.

The bubble column reactor of 10 and 20 L capacity was designed to bio-mitigate 10% CO (g) with 90% air utilizing thermophilic bacteria (Bacillus cereus SSLMC2). The maximum biomass yield during the growth phase was obtained as 9.14 and 10.

Remediation of multifarious metal ions and molecular docking assessment for pathogenic microbe disinfection in aqueous solution by waste-derived Ca-MOF.

The present study demonstrates an eco-friendly and cost-effective synthesis of calcium terephthalate metal-organic frameworks (Ca-MOF). The Ca-MOF were composed of metal ions (Ca) and organic ligands (terephthalic acid; TPA); the former was obtained from egg shells, and the latter was obtained from processing waste plastic bottles. Detailed characterization using standard techniques confirmed the synthesis of Ca-MOF with an average particle size of 461.

Phylloplane fungus Curvularia dactyloctenicola VJP08 effectively degrades commercially available PS product.

Polystyrene (PS), a widely produced plastic with an extended carbon (C-C) backbone that resists microbial attack, is produced in enormous quantities throughout the World. Naturally occurring plasticizers such as plant cuticle and lignocelluloses share similar properties to synthetic plastics such as hydrophobicity, structural complexity, and higher recalcitrance to degradation. In due course of time, phytopathogenic fungi have evolved strategies to overcome these limitations and utilize lignocellulosic waste for their nutrition.

Rhamnolipid production by (SSL-4) on waste engine oil (WEO): Taguchi optimization, soil remediation, and phytotoxicity investigation.

Environmental concerns and rising biosurfactant demand emphasize the need for this study. The objective is to maximize rhamnolipid-biosurfactant production by (SSL-4) utilizing waste engine oil (WEO) as the sole substrate for use in soil bioremediation and commercial production. Using an L Taguchi orthogonal array, a signal-to-noise ratio, and an analysis of variance (ANOVA), the effects of environmental (pH, incubation temperature) and dietary parameters (carbon source concentration, carbon/nitrogen (C/N) and carbon/phosphorus (C/P) ratio) are examined.

Flexible Fiberoptic Bronchoscopy in Non-ventilated Children in Pediatric Intensive Care Unit: Utility, Interventions and Safety.

Objective: To study the utility of flexible fiberoptic bronchoscopy (FFB), and its effects on oxygenation and hemodynamics in children while on respiratory assist devices.

Materials And Methods: The data of non-ventilated patients who underwent FFB during their stay in the PICU from January 2012 to December 2019 was retrieved from medical, nurses, and bronchoscopy records. The study parameters, demography, diagnosis, indication, and findings of FFB and interventions done after FFB, were noted, and also the oxygenation and hemodynamic parameters before, during and 3 hours after FFB.

Production, characterization, and kinetic modeling of biosurfactant synthesis by Pseudomonas aeruginosa gi |KP 163922|: a mechanism perspective.

Kinetic studies and modeling of production parameters are essential for developing economical biosurfactant production processes. This study will provide a perspective on mechanistic reaction pathways to metabolize Waste Engine Oil (WEO). The results will provide relevant information on (i) WEO concentration above which growth inhibition occurs, (ii) chemical changes in WEO during biodegradation, and (iii) understanding of growth kinetics for the strain utilizing complex substrates.

Pathological Correlation of a Cardiac Mass with Multimodality Imaging.

Cardiac masses are rarely encountered in clinical practice and can lead to severe hemodynamic consequences. In addition to clinical cues, noninvasive modalities can play an important role in characterization of these masses and therefore their diagnosis and management planning. Here in this case report, we describe the use of various forms of noninvasive imaging techniques to narrow the differential diagnosis and form an operative plan for a cardiac mass later identified as a benign myxoma originating from the right ventricle on histological examination.

Study of thermodynamics of a thermal electron in scattering.

This work presents the study of the thermodynamic properties of thermal electrons participating in scattering events. This is necessary because scattering with a thermal electron in presence of a laser field was not studied yet and it reduces the complexity of event measurement (differential cross-section). To study thermodynamic properties, the authors model the thermal Hamiltonian in presence of a laser field and used it to study the thermodynamic properties using the partition function.

Uretero-Sciatic Hernia (Lindbom Hernia): A Case Report and Long-Term Follow-Up.

Ureteric herniation through the posterior pelvic wall is one of the rarest variants of hernias and causes of ureteric obstruction. The clinical features span from asymptomatic to a presentation with severe flank pain and life-threatening infection secondary to ureteric obstruction. The diagnosis needs a high index of suspicion and timely, appropriate radiological investigation.

One-pot synthesis of metal oxide-clay composite for the evaluation of dye removal studies: Taguchi optimization of parameters and environmental toxicity studies.

The present study demonstrates the synthesis of eco-friendly metal oxide-clay composites (MgO-clay and CaO-clay) with phytochemical functionalization. The physical and chemical properties of prepared composites were characterized using standard techniques viz. scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction.

Indication-based timing of tracheostomy and its effects on outcome in the pediatric intensive care unit.

Objectives: The objective of study was to find an association between the timing of tracheostomy with duration of mechanical ventilation (MV) and length of stay (LOS) in pediatric intensive care unit (PICU) and hospital.

Methods: The data were collected prospectively from 2000 to 2018 and were analyzed retrospectively. Data included clinical diagnosis, indication, and duration (days) of MV, LOS in PICU and hospital before and after tracheostomy.