Multisystem inflammatory syndrome in children (MIS-C) presenting with valvulitis, myocarditis, and QTc prolongation: A case report from Saudi Arabia.

Rationale: This case report highlights the complex clinical course and successful multidisciplinary management of a pediatric patient with multisystem inflammatory syndrome in children (MIS-C), who posed clinical dilemma at presentation. It underscores the ongoing clinical relevance of MIS-C as a post-Coronavirus disease 2019 sequelae and emphasizes the importance of maintaining a high index of suspicion for MIS-C in pediatric differential diagnoses, especially when symptoms overlap with other common conditions.

Patient Concerns: An 11-year-old previously healthy Saudi girl presented with gastrointestinal symptoms initially suggestive of acute appendicitis.

Harnessing Digital Phenotyping for Early Self-Detection of Psychological Distress.

Psychological distress remains a significant public health concern, particularly among youth. With the growing integration of mobile and wearable technologies into daily life, digital phenotyping has emerged as a promising approach for early self-detection and intervention in psychological distress. The study aims to determine how behavioral and device-derived data can be used to identify early signs of emotional distress and to develop and evaluate a prototype system that enables users to self-detect these early warning signs, ultimately supporting early intervention and improved mental health outcomes.

mHealth Applications in Saudi Arabia: Current Features and Future Opportunities.

The rapid growth of mobile health (mHealth) applications has revolutionized healthcare delivery worldwide. These digital tools encompass a broad array of functionalities, including telemedicine, appointment scheduling, medication management, and health data tracking, all of which contribute to enhanced healthcare accessibility, increased patient engagement, and improved operational efficiency. However, despite their increasing prominence, the design, deployment, and use of mHealth applications continue to face several challenges, such as usability issues and overall sustained adoption.

Generative AI in Game Design: Enhancing Creativity or Constraining Innovation?

Generative AI tools are increasingly being integrated into game design and development workflows, offering new possibilities for creativity, efficiency, and innovation. This paper explores the evolving role of these tools from the perspective of game designers and developers, focusing on the benefits and challenges they present in fostering creativity. Through a mixed-method study, we conducted an online survey ( = 42) with game design professionals, followed by in-depth online interviews ( = 9), to investigate how generative AI influences the creative process, decision-making, and artistic vision.

Down syndrome patients with normal hearts: are they really normal?

Even though congenital heart disease is a common finding in down syndrome (DS) patients, some of them have anatomically normal hearts. However, the term "normal" might not be suitable, as these patients usually suffer from functional cardiac dysfunction. Several research highlighted that despite the absence of anatomical heart defects, subtle cardiac function derangements are present in DS patients.

Influence of Er: Cr: YSGG laser on adhesive strength and microleakage of dentin bonded to resin composite. In-vitro study.

Background: The aim of this study was to evaluate the surface treatment of dentin with phototherapy (ER-CR-YSGG laser) in the presence of different bonding systems on their shear bond strength and microleakage.

Materials And Methods: Eighty intact human third molars were divided into two groups. Forty teeth were treated with conventional flat wheel diamond bur and the remaining forty were treated with Er Cr YSGG laser (phototherapy).