Mining tailings as a frontier for sustainable nanomaterials: advancing circular economy and environmental innovation.

The mining industry plays a crucial role in global economic growth and technological advancement, faces persistent challenges in managing mining tailings pose significant environmental and societal risks. Mine tailings are primarily composed of finely milled rock, water, and extraction chemicals, often lead to soil and water contamination, atmospheric pollution, and ecological disruption when improperly managed. Recent advancements have transformed mining tailings from waste into valuable resources for synthesizing nanomaterials (NMs) through sustainable extraction processes.

Clinical Validation of Respiratory Rate Estimation Using Acoustic Signals from a Wearable Device.

: Respiratory rate (RR) is a clinical measure of breathing frequency, a vital metric for clinical assessment. However, the recording and documentation of RR are considered to be extremely poor due to the limitations of the current approaches to measuring RR, including capnography and manual counting. We conducted a validation of the automatic RR measurement capability of AcuPebble RE100 (Acurable, London, UK) against a gold-standard capnography system and a type-III cardiorespiratory polygraphy system in two independent prospective and retrospective studies.

Optimizing yield and water productivity in summer mung bean (Vigna radiata L.) through crop residue management and irrigation strategies.

A multi-season research trial entitled 'crop residue management effects on yield and water productivity of summer mung bean (Vigna radiata L.) under different irrigation regimes in Indian Punjab' was conducted at Punjab Agricultural University (PAU), Regional Research Station (RRS), Bathinda, during rabi 2020 and 2021. The field experiment was conducted in a split-plot layout with nine treatment combinations and replicated thrice.

Empowering precision medicine: regenerative AI in breast cancer.

Regenerative AI is transforming breast cancer diagnosis and treatment through enhanced imaging analysis, personalized medicine, drug discovery, and remote patient monitoring. AI algorithms can detect subtle patterns in mammograms and other imaging modalities with high accuracy, potentially leading to earlier diagnoses. In treatment planning, AI integrates patient-specific data to predict individual responses and optimize therapies.

Violence in the emergency department: a quantitative survey study of healthcare providers in India.

Background: Workplace violence (WPV) in Emergency Departments (EDs) is an increasingly recognized challenge healthcare providers face in low-resource settings. While studies have highlighted the increased prevalence of WPV in healthcare, most of the existing research has been conducted in developed countries with established laws and repercussions for violence against healthcare providers. More data on WPV against ED providers practicing in low-resource settings is necessary to understand these providers' unique challenges.

Agronomic bio-fortification of wheat ( L.) to alleviate zinc deficiency in human being.

Worldwide, 40% population consumes wheat ( L.) as a staple food that is low in zinc (Zn) content. Zn deficiency is a major micronutrient disorder in crop plants and humans worldwide, adversely impacting agricultural productivity, human health and socio-economic concern.

Sleep Posture Detection Using an Accelerometer Placed on the Neck.

Sleep position monitoring is key when attempting to address posture triggered sleep disorders. Many studies have explored sleep posture detection from a dedicated physical sensing channel exploiting optimum body locations, such as the torso; or alternatively non-contact approaches. But, little work has been done to try to detect sleep position from a body location which, whilst being suboptimal for that purpose, does however allow for better extraction of more critical biomarkers from other sensing modalities, making possible multi-modal monitoring in certain clinical applications.

Effects of denoising strategies on R-wave detection in ECG analysis.

The use of ECG in cardiovascular health monitoring is well established. The signal is collected using specialised equipment, capturing the electrical discharge properties of the human heart. This produces a well-structured signal trace, which can be characterised through its peaks and troughs.

Analysis of the factors affecting the adoption and compliance of the NHS COVID-19 mobile application: a national cross-sectional survey in England.

Objectives: To conduct an independent study investigating how adults perceive the usability and functionality of the 'National Health Service (NHS) COVID-19' application (app). This study aims to highlight strengths and provide recommendations to improve adoption of future contact tracing developments.

Design: A 60-item, anonymous online questionnaire, disseminated through social media outlets and email lists by a team from Imperial College London.

An observational study of switching infliximab biosimilar: no adverse impact on inflammatory bowel disease control or drug levels with first or second switch.

Background: Biologics account for a significant cost in inflammatory bowel disease (IBD) management; however, switching from infliximab originator to its biosimilars has enabled cost saving without compromising disease control. The effects on IBD activity and infliximab trough levels of a second switch to another biosimilar are, however, uncertain.

Aims: To assess the effects on disease activity and infliximab trough levels associated with switching from infliximab biosimilar CT-P13 to another biosimilar SB2 and compare outcomes in those switching for the first and second time.

Rifampicin and isoniazid behave as non-creatinine chromogens and interfere with Jaffe's reaction: A phenomenon with the potential to give a false-positive result in creatinine estimation.

Tuberculosis is a health concern worldwide. The anti-tubercular drugs (particularly rifampicin) used for its management offers side effects like acute kidney injury. Creatinine, which is recognised as an important biomarker for the renal function, is commonly estimated with Jaffe's reaction (alkaline picrate reaction).

Treatment options for alcoholic and non-alcoholic fatty liver disease: A review.

Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are serious health problems worldwide. These two diseases have similar pathological spectra, ranging from simple steatosis to hepatitis to cirrhosis and hepatocellular carcinoma. Although most people with excessive alcohol or calorie intake display abnormal fat accumulation in the liver (simple steatosis), a small percentage develops progressive liver disease.

Man's best friend: How humans can develop Dirofilaria immitis infections.

Canine heartworm, Dirofilaria immitis, is a nematode parasite that infects dogs by way of mosquito bite. Rarely, humans play accidental hosts to this parasite and are not a suitable environment for the nematode to live. As the parasite dies in the pulmonary vessels it embolizes the vessels causing infarction and eventual nodule formation in the lungs.

Intrathecal dextmedetomidine to reduce shoulder tip pain in laparoscopic cholecystectomies under spinal anesthesia.

Background: General anesthesia as a technique for laparoscopic cholecystectomies has disadvantage in terms of the stress response, lack of postoperative analgesia and emesis. Regional anesthesia offers advantages over general anesthesia in terms of cost, postoperative analgesia, intact respiratory control mechanism and early ambulation. Shoulder tip pain remains the main concerns that can be alleviated by adding various adjuvants to local anesthetics.

A speculated ribozyme site in the herpes simplex virus type 1 latency-associated transcript gene is not essential for a wild-type reactivation phenotype.

During herpes simplex virus-1 (HSV-1) latency in sensory neurons, LAT (latency-associated transcript) is the only abundantly expressed viral gene. LAT plays an important role in the HSV-1 latency-reactivation cycle, because LAT deletion mutants have a significantly decreased reactivation phenotype. Based solely on sequence analysis, it was speculated that LAT encodes a ribozyme that plays an important role in how LAT enhances the virus' reactivation phenotype.

Anti-free radical activities of kaempferol isolated from Acacia nilotica (L.) Willd. Ex. Del.

In the present study the polyphenolic compound has been isolated from methanol extract of Acacia nilotica Willd. Ex. Del.

Evaluation of antioxidant potential of ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn.

The present study estimates the free radical scavenging activity of the ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn in different assays viz. 1'-1' diphenyl-2'picrylhydrazyl (DPPH), deoxyribose (site specific and non-site specific), relative reducing power, chelating power and lipid peroxidation.