Mariette: A screening test for reading errors in primary school.

Dyslexia is a multifaceted condition with diverse manifestations, yet assessment tools too often target limited subtypes, creating diagnostic gaps. This study examines the progression of dyslexia-related reading errors across primary school in typically developing readers, using the Mariette, a French nonsense-text reading screener. Analysis of 812 French children (grades 1-5) revealed systematic decreases in error rates with age, following distinct developmental trajectories.

The Neural Bases of Graphical Perception: A Novel Instance of Cultural Recycling?

Graphical representations of quantitative data abound in our culture, and yet the brain mechanisms of graphicacy, by which viewers quickly extract statistical information from a data graphic, are unknown. Here, using scatterplots as stimuli, we tested two hypotheses about the brain areas underlying graphicacy. First, at the perceptual level, we hypothesized that the visual processing of scatterplots and their main trend recycles cortical regions devoted to the perception of the principal axis of objects.

The compositional nature of number concepts: Insights from number frequencies.

The frequency with which humans use words provides a window into the psychological representation of the corresponding concepts. Capitalizing on the availability of massive lexical databases, we evaluate the frequency with which specific number words and their combinations (e.g.

The superiority of graphics over text in long-term memory retention.

Graphical representations of data are pervasive in modern communication and are often used to convey socio-economic, scientific, and medical information. Despite their popularity, it is still unknown whether they can enhance the long-term retention of their content. We conducted a delayed-recall task with psychology undergraduates (N = 92), in which participants read about the evolution of a socio-economic phenomenon, with five to six datapoints presented as graphics, text, or table; recall was operationalized as correct reporting of the trend in the data, 2 h after the information was presented.

Adversarial testing of global neuronal workspace and integrated information theories of consciousness.

Different theories explain how subjective experience arises from brain activity. These theories have independently accrued evidence, but have not been directly compared. Here we present an open science adversarial collaboration directly juxtaposing integrated information theory (IIT) and global neuronal workspace theory (GNWT) via a theory-neutral consortium.

Origins of numbers: a shared language-of-thought for arithmetic and geometry?

Concepts of exact number are often thought to originate from counting and the successor function, or from a refinement of the approximate number system (ANS). We argue here for a third origin: a shared language-of-thought (LoT) for geometry and arithmetic that involves primitives of repetition, concatenation, and recursive embedding. Applied to sets, those primitives engender concepts of exact integers through recursive applications of additions and multiplications.

A dynamic bifurcation mechanism explains cortex-wide neural correlates of conscious access.

Conscious access is suggested to involve "ignition," an all-or-none activation across cortical areas. To elucidate this phenomenon, we carry out computer simulations of a detection task using a mesoscale connectome-based model for the multiregional macaque cortex. The model uncovers a dynamic bifurcation mechanism that gives rise to ignition in a network of associative regions.

Visual mental imagery in typical imagers and in aphantasia: A millimeter-scale 7-T fMRI study.

Most of us effortlessly describe visual objects, whether seen or remembered. Yet, around 4% of people report congenital aphantasia: they struggle to visualize objects despite being able to describe their visual appearance. What neural mechanisms create this disparity between subjective experience and objective performance? Aphantasia can provide novel insights into conscious processing and awareness.

Brain areas for reversible symbolic reference, a potential singularity of the human brain.

The emergence of symbolic thinking has been proposed as a dominant cognitive criterion to distinguish humans from other primates during hominisation. Although the proper definition of a symbol has been the subject of much debate, one of its simplest features is bidirectional attachment: the content is accessible from the symbol, and vice versa. Behavioural observations scattered over the past four decades suggest that this criterion might not be met in non-human primates, as they fail to generalise an association learned in one temporal order (A to B) to the reverse order (B to A).

Unpacking the complexities of consciousness: Theories and reflections.

As the field of consciousness science matures, the research agenda has expanded from an initial focus on the neural correlates of consciousness, to developing and testing theories of consciousness. Several theories have been put forward, each aiming to elucidate the relationship between consciousness and brain function. However, there is an ongoing, intense debate regarding whether these theories examine the same phenomenon.

Can non-human primates extract the linear trend from a noisy scatterplot?

Recent studies showed that humans, regardless of age, education, and culture, can extract the linear trend of a noisy scatterplot. Although this capacity looks sophisticated, it may simply reflect the extraction of the principal trend of the graph, as if the cloud of dots was processed as an oriented object. To test this idea, we trained Guinea baboons to associate arbitrary shapes with the increasing or decreasing trends of noiseless and noisy scatterplots, while varying the number of points, the noise level, and the regression slope.

Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex.

The brain predicts regularities in sensory inputs at multiple complexity levels, with neuronal mechanisms that remain elusive. Here, we monitored auditory cortex activity during the local-global paradigm, a protocol nesting different regularity levels in sound sequences. We observed that mice encode local predictions based on stimulus occurrence and stimulus transition probabilities, because auditory responses are boosted upon prediction violation.

Modality-Specific and Amodal Language Processing by Single Neurons.

According to psycholinguistic theories, during language processing, spoken and written words are first encoded along independent phonological and orthographic dimensions, then enter into modality-independent syntactic and semantic codes. Non-invasive brain imaging has isolated several cortical regions putatively associated with those processing stages, but lacks the resolution to identify the corresponding neural codes. Here, we describe the firing responses of over 1000 neurons, and mesoscale field potentials from over 1400 microwires and 1500 iEEG contacts in 21 awake neurosurgical patients with implanted electrodes during written and spoken sentence comprehension.

Mapping and modeling the semantic space of math concepts.

Mathematics is an underexplored domain of human cognition. While many studies have focused on subsets of math concepts such as numbers, fractions, or geometric shapes, few have ventured beyond these elementary domains. Here, we attempted to map out the full space of math concepts and to answer two specific questions: can distributed semantic models, such a GloVe, provide a satisfactory fit to human semantic judgements in mathematics? And how does this fit vary with education? We first analyzed all of the French and English Wikipedia pages with math contents, and used a semi-automatic procedure to extract the 1000 most frequent math terms in both languages.

Cracking the neural code for word recognition in convolutional neural networks.

Learning to read places a strong challenge on the visual system. Years of expertise lead to a remarkable capacity to separate similar letters and encode their relative positions, thus distinguishing words such as FORM and FROM, invariantly over a large range of positions, sizes and fonts. How neural circuits achieve invariant word recognition remains unknown.

Cognitive Motor Dissociation in Disorders of Consciousness.

Background: Patients with brain injury who are unresponsive to commands may perform cognitive tasks that are detected on functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). This phenomenon, known as cognitive motor dissociation, has not been systematically studied in a large cohort of persons with disorders of consciousness.

Methods: In this prospective cohort study conducted at six international centers, we collected clinical, behavioral, and task-based fMRI and EEG data from a convenience sample of 353 adults with disorders of consciousness.

Transient brain activity dynamics discriminate levels of consciousness during anesthesia.

The awake mammalian brain is functionally organized in terms of large-scale distributed networks that are constantly interacting. Loss of consciousness might disrupt this temporal organization leaving patients unresponsive. We hypothesize that characterizing brain activity in terms of transient events may provide a signature of consciousness.

Individual Brain Charting dataset extension, third release for movie watching and retinotopy data.

The Individual Brain Charting (IBC) is a multi-task functional Magnetic Resonance Imaging dataset acquired at high spatial-resolution and dedicated to the cognitive mapping of the human brain. It consists in the deep phenotyping of twelve individuals, covering a broad range of psychological domains suitable for functional-atlasing applications. Here, we present the inclusion of task data from both naturalistic stimuli and trial-based designs, to uncover structures of brain activation.

Characterizing different types of developmental dyslexias in French: The Malabi screener.

Reading is a complex process involving multiple stages. An impairment in any of these stages may cause distinct types of reading deficits- distinct types of dyslexia. We describe the Malabi, a screener to identify deficits in various orthographic, lexical, and sublexical components of the reading process in French.

Stanislas Dehaene.

Stanislas Dehaene is a cognitive neuroscientist elucidating the biological mechanisms that give rise to human perception and cognition. In a conversation with Neuron, he talks about his ongoing interest in consciousness research, the role of theory in neuroscience, and his current work on education and the science of learning.

Examining the Impact of Reading Fluency on Lexical Decision Results in French 6th Graders.

Purpose: How does lexical decision behavior vary in students with the same grade level (all students were in their first year of middle-school), but different levels of reading fluency? Here, we tested a prediction of the dual-route model: as fluency increases, variations in the results may reflect a decreasing reliance on decoding and an increasing reliance on the lexical route.

Method: 1,501 French 6 graders passed a one-minute speeded reading-aloud task evaluating fluency, and a ten-minute computerized lexical decision task evaluating the impact of lexicality, length, word frequency and pseudoword type.

Results: As predicted, the word length effect varied dramatically with reading fluency, with the least fluent students showing a length effect even for frequent words.

Spontaneously emerging internal models of visual sequences combine abstract and event-specific information in the prefrontal cortex.

When exposed to sensory sequences, do macaque monkeys spontaneously form abstract internal models that generalize to novel experiences? Here, we show that neuronal populations in macaque ventrolateral prefrontal cortex jointly encode visual sequences by separate codes for the specific pictures presented and for their abstract sequential structure. We recorded prefrontal neurons while macaque monkeys passively viewed visual sequences and sequence mismatches in the local-global paradigm. Even without any overt task or response requirements, prefrontal populations spontaneously form representations of sequence structure, serial order, and image identity within distinct but superimposed neuronal subspaces.

Tracking the neural codes for words and phrases during semantic composition, working-memory storage, and retrieval.

The ability to compose successive words into a meaningful phrase is a characteristic feature of human cognition, yet its neural mechanisms remain incompletely understood. Here, we analyze the cortical mechanisms of semantic composition using magnetoencephalography (MEG) while participants read one-word, two-word, and five-word noun phrases and compared them with a subsequent image. Decoding of MEG signals revealed three processing stages.

Brain-imaging evidence for compression of binary sound sequences in human memory.

According to the language-of-thought hypothesis, regular sequences are compressed in human memory using recursive loops akin to a mental program that predicts future items. We tested this theory by probing memory for 16-item sequences made of two sounds. We recorded brain activity with functional MRI and magneto-encephalography (MEG) while participants listened to a hierarchy of sequences of variable complexity, whose minimal description required transition probabilities, chunking, or nested structures.

Does word flickering improve reading? Negative evidence from four experiments using low and high frequencies.

Does word flickering facilitate reading? Despite a lack of scientific evidence, flickering glasses and lamps for dyslexia are being marketed in various countries. We conducted four experiments to assess their efficacy. Two experiments involved a computerized lexical decision task with constant display or low-frequency flickering (10 or 15 Hz).