Publications by authors named "Sotharith Bory"

Unlabelled: Despite high levels of global concern, little is known about the epidemiology of () infection (CDI) in Cambodia. This study aimed to identify the prevalence and risk factors for CDI, and molecular types of in hospitalized adults at Calmette Hospital, Phnom Penh, Cambodia. Stool samples were collected from 263 hospitalized adults between June and September 2022 and tested for using direct and enrichment cultures.

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  • Antimicrobial resistance surveillance is crucial for informed antibiotic prescribing and infection control, yet many systems lack comprehensive patient data, especially in low- and middle-income countries (LMICs).
  • The ACORN II initiative builds on the WHO's surveillance framework to focus on healthcare-related infections, aiming to create effective, routine surveillance systems that capture critical patient information.
  • The project emphasizes improving local antibiotic practices through streamlined data collection and the use of an R Shiny application for analytics, enhancing overall clinical decision-making and infection control policies.
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  • The study analyzed data on human trichinellosis outbreaks and seroprevalence in Southeast Asia from 2001 to 2021, highlighting low infection rates in countries like Laos and Vietnam.
  • Cultural practices in communities that consume pork contribute significantly to the transmission of the disease, with human outbreaks and cases being relatively rare in the region.
  • Trichinellosis tends to be subclinical, with severe cases occurring more often in males, suggesting that the disease might be under-diagnosed and is considered endemic in Southeast Asia.
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The degree of surveillance data and control strategies for invasive meningococcal disease (IMD) varies across the Asia-Pacific region. IMD cases are often reported throughout the region, but the disease is not notifiable in some countries, including Myanmar, Bangladesh and Malaysia. Although there remains a paucity of data from many countries, specific nations have introduced additional surveillance measures.

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  • * Clinical symptoms observed in infected patients included muscle pain, swelling, fatigue, and fever, alongside increased enzyme levels and blood eosinophils.
  • * Laboratory analysis confirmed the presence of Trichinella papuae in biopsy samples, a species previously documented in Papua New Guinea and in outbreaks in Thailand.
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Enteric fever is a systemic bacterial infection in humans that is endemic in Cambodia and for which antibiotic resistance is increasingly reported. To guide public health programs, this qualitative study sought to explore community perceptions on transmission and treatment. Participant observation was carried out in hospital settings, pharmacies, and at a community level in Phnom Penh.

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Melioidosis is an endemic infection in Cambodia, a lower middle income SE Asian country. Despite more laboratories isolating and identifying in recent years, the infection remains under-recognised and under-diagnosed, particularly in the adult population. Lack of knowledge about the disease and lack of utilization of microbiology laboratories contributes to this, along with laboratory capacity issues.

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Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases and deaths are estimated to occur in low and middle-income countries. Barriers to reducing the global burden of sepsis include difficulty quantifying attributable morbidity and mortality, low awareness, poverty and health inequity, and under-resourced and low-resilience public health and acute health care delivery systems.

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