Publications by authors named "Simin Torabinezhad"

An inflammatory myofibroblastic tumor (IMT) is a rare neoplasm with an unclear origin that can arise anywhere on the body. It contains spindle cells (myofibroblasts) with different inflammatory elements. Primary IMT of the kidney is a clinically rare disease and is difficult to differentiate from other renal malignancies.

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Malignant nerve sheath tumors (MPNSTs) are rare sarcomas tumors which rarely present as intrapelvic mass and are hard to diagnose clinically. We present a 29-year-old male patient presented with acute urinary retention and was diagnosed with large intrapelvic mass. After complete surgical resection, the histopathology confirmed the diagnosis of low MPNST.

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Introduction: Renal involvement is seen in about 40-82% of systemic lupus erythematosus (SLE) Asian patients. The exact diagnosis and classification of lupus nephritis are important for treatment and prognosis. This study aimed to investigate the value of electron microscopy (EM) in the diagnosis and classification of lupus nephritis compared with light microscopy.

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No large study has been conducted on biopsy-proven nephropathies. Our aim was to report clinical and pathological pattern of kidney disease diagnosed by kidney biopsy in our center. This is a retrospective study on kidney biopsy during 7 years; we analyzed the results of kidney biopsies and their clinical data.

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Background: Acute interstitial nephritis (AIN) is an emerging cause of acute kidney injury (AKI) during the recent years.

Objectives: There is no data about prevalence, causes, clinical manifestation and outcomes of AIN in our region. Hence, in this study we aimed to find the prevalence of AIN and describe the causes, clinical presentation, and the outcome of AIN in the native kidney biopsies.

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Article Synopsis
  • - The study investigates the protective effects of edaravone against chronic kidney damage caused by Cyclosporine A (CsA), an immunosuppressant linked to kidney toxicity via oxidative stress.
  • - Male Sprague-Dawley rats were used to assess various treatment combinations, measuring factors like blood urea nitrogen and serum creatinine levels, as well as kidney tissue health through histopathological evaluations.
  • - Results showed that edaravone (10 mg/kg) significantly reduced oxidative stress and kidney injury from CsA, particularly enhancing kidney protection in conjunction with the iNOS inhibitor, while it did not notably affect eNOS levels.
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Background: The main morphologic differential diagnosis of intra-ductal carcinoma of prostate (IDC-P) is high grade prostatic intraepithelialneoplasia (HGPIN). Since IDC-P, unlike PIN, was strongly correlated with aggressive prostate cancer, differentiation of these is too necessary. So we evaluated immunohistopathological patterns and the prognostic factors of IDC-P and HGPIN, in radical prostatectomy samples.

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Introduction: Mutations in podocin (NPHS2) gene have the key role in the pathogenesis of steroid-resistant nephrotic syndrome (SRNS) in children, but data is scarce regarding their prevalence and natural course among different all ethnic groups. This study was aimed to demonstrate the spectrum of NPHS2 mutations in children with SRNS and to compare the clinical course of disease in patients with and without mutation.

Materials And Methods: All 8 exons of NPHS2 were sequenced in 99 children, including 49 with SRNS and 50 with steroid-sensitive nephrotic syndrome (control group) by DNA sequencing.

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Study Design: An experimental pilot study using an acrylic interbody cage in a dog cervical spine fusion model.

Objective: To compare bony fusion in autologous bone grafting with a novel acrylic cage in terms of preservation of disc height, biomechanical properties, and histologic characteristics.

Summary Of Background Data: Degenerative diseases of cervical intervertebral discs are commonly treated by anterior decompression and interbody fusion.

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