Real-time beat-to-beat pulse wave velocity estimation: a quality-driven approach using laser Doppler vibrometry.

Arterial stiffness, a key cardiovascular risk marker, is typically assessed via carotid-femoral pulse wave velocity (cf-PWV), the gold-standard method. In this study, we introduce CAPE (Continuous Automatic PWV Estimation), an innovative framework for near real-time cf-PWV estimation based on beat-to-beat analysis of laser-Doppler vibrometry (LDV) signals. CAPE integrates automatic fiducial point detection, systematic signal quality control, and a cross-channel strategy to provide a highly reliable assessment of cf-PWV.

Heart-carotid pulse-wave velocity via laser-Doppler vibrometry as a biomarker for arterial stiffening: a feasibility study.

. Large artery stiffening leads to an increase in cardiovascular risk and organ damage of the kidneys, brain or the heart. Biomarkers that allow for early detection of this phenomenon are a point of interest in research, with pulse-wave velocity (PWV) having been proven useful in predicting and monitoring arterial stiffness.

Template Matching and Matrix Profile for Signal Quality Assessment of Carotid and Femoral Laser Doppler Vibrometer Signals.

Laser-Doppler Vibrometry (LDV) is a laser-based technique that allows measuring the motion of moving targets with high spatial and temporal resolution. To demonstrate its use for the measurement of carotid-femoral pulse wave velocity, a prototype system was employed in a clinical feasibility study. Data were acquired for analysis without prior quality control.