Neuroleptic Malignant Syndrome: A Retrospective Chart Review from a Tertiary Neuropsychiatric Facility.

Background And Objective: Neuroleptic malignant syndrome (NMS) is a potentially fatal reaction to antipsychotic drugs. Our study aimed to describe the characteristics of NMS patients and identify the trends of symptom profile.

Materials And Methods: We conducted a retrospective chart review of patients diagnosed with NMS and admitted to the intensive care unit (ICU) of a tertiary health-care center between January 2017 and March 2023.

Bilateral recurrent painful ophthalmoplegic neuropathy in an adolescent female.

Recurrent painful ophthalmoplegic neuropathy (RPON) is a rare condition characterised by recurrent episodes of headache followed by ophthalmoplegia.An adolescent female presented with a throbbing unilateral headache associated with photophobia and phonophobia, progressing to binocular diplopia after 10-12 hours. She had two prior episodes that resolved spontaneously over 2-3 weeks.

High resolution ultrasound in subclinical diabetic neuropathy: A potential screening tool.

Introduction: Detection of subclinical neuropathy can aid in triage, timely intervention and dedicated care to reduce disease progression and morbidity. High resolution sonography has emerged as a promising technique for evaluation of peripheral nerves. The aim of the present study was to assess the utility of high resolution sonography in screening diabetic patients for subclinical neuropathy.

Congenital Myopathies: A Clinicopathological Study of 10 Cases in a Tertiary Care Hospital of North India.

Objective: Congenital myopathies (CMs) are rare neuromuscular disorders. Through this article, authors want to present a clinicopathological study of 10 cases of CM.

Materials And Methods: The study included patients with histopathologically confirmed CM attending the neurology services at the Institute of Human Behavior and Allied Sciences for 2 years.

Neurological Associations of COVID-19-Do We Know Enough: A Tertiary Care Hospital Based Study.

The neurotrophic potential of SARS-CoV-2 virus is manifesting as various neurological disorders in the present pandemic. Nervous system involvement can be due to the direct action of the virus on the brain tissue or due to an indirect action through the activation of immune-mediated mechanisms. This study will discuss the detailed systematically evaluated clinical profile and relevant investigations and outcome of 14 laboratory confirmed SARS-CoV-2 positive patients presenting with neurological signs and symptoms.

Moyamoya Disease Presenting as Alternating Hemiparesis with Relapsing Remitting Hemichorea: An Unusual Manifestation.

Case: Moyamoya disease (MMD) is a neurological disease involving internal carotid artery (ICA) leading to its occlusion. Among the children, the disease presents as ischemic strokes, whereas in adults, it presents as hemorrhagic strokes. Movement disorder among the MMD is very rare with varied presentation.

Saving the brain initiative - Developing an effective hub-and-spoke model to improve the acute stroke management pathways in urban India.

Objectives: We aimed to develop and evaluate a hub-and-spoke model in the East Delhi by assessing knowledge and creating awareness through sensitization programs in target communities and among general physicians (GPs) along with implementation of a standard stroke management protocol (SMP) at our institute in order to extend the benefit of thrombolytic therapy.

Methods: We carried out a prospective interventional study using sensitization program comprising 1046 community participants and 101 GPs under "Saving the Brain Initiative" project. Network included one hub and six nearby spoke hospitals.

Chin fasciculations in Madras motor neuron disease: a new clinical feature.

The characteristic features of Madras motor neuron disease (MMND) are onset in the young in the first two decades, sporadic occurrence, facial and bulbar paralysis, sensorineural hearing impairment, asymmetrical weakness of limbs and pyramidal signs with a slow progression. The majority of the cases reported are from South India. MMND variant has the additional features of optic atrophy and cerebellar signs.

Subacute sclerosing panencephalitis presenting as acute disseminated encephalomyelitis and pseudotumour cerebri.

Subacute sclerosing panencephalitis (SSPE) is a chronic progressive encephalitis of childhood and young adults due to persistent measles virus infection. The usual age of onset is between 5 and 15 years. There are wide varieties of presentations of SSPE described in the literatures.

Universal cone angle of ac electrosprays due to net charge entrainment.

The half-angle of an ac cone is shown to exhibit a universal (length-scale independent) asymptotic value of 12.6 degrees at high-permittivity ratio, which is quite distinct from the 49.3 degrees of dc Taylor cones.

Coupling between precipitation and contact-line dynamics: multiring stains and stick-slip motion.

The contact line in an evaporating drop can stay pinned to form a single ring or can shrink in a discontinuous stepwise manner and generate multiple rings. We demonstrate the latter with DNA solutions and attribute it to a pinning-depinning cycle that generates new contact lines. The new contact line recedes after depinning and is repinned at an internal precipitate ring that determines the location of the next contact line.

Evaporative self-assembly from complex DNA-colloid suspensions.

Evaporation-induced pattern formation has attracted considerable attention as a simple yet versatile method for generating self-assembled structures that have broad applications from photonic devices to biomacromolecular recognition. Previous study of evaporative self-assembly has mainly focused on single nonvolatile component systems, and the driving mechanisms have been extensively investigated. In contrast, pattern formation from evaporating multicomponent systems, despite its wide existence in nature and numerous engineering applications, has been rarely explored.

Rapid bioparticle concentration and detection by combining a discharge driven vortex with surface enhanced Raman scattering.

Rapid concentration and detection of bacteria in integrated chips and microfluidic devices is needed for the advancement of lab-on-a-chip devices because current detection methods require high concentrations of bacteria which render them impractical. We present a new chip-scale rapid bacteria concentration technique combined with surface-enhanced Raman scattering (SERS) to enhance the detection of low bacteria count samples. This concentration technique relies on convection by a long-range converging vortex to concentrate the bacteria into a packed mound of 200 mum in diameter within 15 min.

Polyhedra formation and transient cone ejection of a resonant microdrop forced by an ac electric field.

New deformation or fission phenomena are reported for microdrops driven by an ac electric field at their resonant frequencies. The Maxwell forces that pull out the vertices from a drop can be enhanced when the ac frequency is comparable to both the drop resonant frequency and the inverse charge relaxation time of the diffuse layer. The selected polyhedra possess symmetries that ensure a global force balance of the Maxwell forces and a linear dimension consistent with a sphere whose nth harmonic (n is up to six in the observation) coincides with the applied ac frequency.