Patterns of Genetic Diversity Within Three California Quail Species Are Best Explained by Climate and Landscape Changes.

Many North American game animals experienced severe population declines during the 19th century due to market hunting. However, estimates of the timing and magnitude of these declines often rely on anecdotal evidence, which makes it difficult to understand the lasting impacts of hunting pressures versus climate or landscape changes on the genetic diversity of contemporary populations. Historical reports suggest the California quail (Callipepla californica) suffered more significant hunting pressure in the late 19th century relative to either Gambel's (Callipepla gambelii) or mountain quail (Oreortyx pictus).

Sex and Age Differences in Exercise Frequency and Exercise Capacity After Home-Based Cardiac Rehabilitation During the Coronavirus Disease 2019 (COVID-19) Pandemic.

Background: The impact of home-based cardiac rehabilitation (HBCR) during the Coronavirus Disease 2019 (COVID-19) pandemic on changes in exercise frequency and capacity according to sex and age has not been studied.

Methods And Results: This cohort study included 118 patients participating in HBCR and 149 patients participating in center-based cardiac rehabilitation (CBCR) for whom data on exercise and peak oxygen uptake (V̇O) were available at program enrollment and completion. Changes in these parameters were compared HBCR and CBCR, and according to sex and age in the HBCR group.

Extracellular tau clearance is governed by its aggregation state and independent of microglial activation by LPS and IFN-γ.

Microglia are the tissue resident macrophages of the brain and their contribution to tau pathology progression remains to be fully understood. In this study, we developed a quantitative platform to elucidate the processing of extracellular tau within human induced pluripotent stem cell (iPSC)-derived microglia. We show that iPSC-derived microglia internalize monomeric and fibrillar tau through different cellular mechanisms and with different clearance kinetics.

RAD (Resist-Accept-Direct) switch points and triggers for adaptation planning.

Climate change is transforming ecosystems globally. The Resist-Accept-Direct (RAD) framework has gained traction within many natural resource management institutions to help consider the decision space in response to this transformation. Because RAD helps manage for directional change, RAD choices entail considering which RAD pathway to implement and for how long.

The HEALERS: a patient, community, and stakeholder advisory board focus group series to refine a novel virtual world-based cardiac rehabilitation intervention and clinical trial.

Background: Cardiac rehabilitation (CR) is a widely underutilized secondary cardiovascular disease prevention strategy, due to a variety of barriers to participation that disproportionately impact women, minoritized racial and ethnic groups, and patients with low socioeconomic status. , a virtual world-based CR (VWCR) program designed by our team in collaboration with patients and community members to mitigate the barriers to CR participation, has demonstrated feasibility and acceptability. In anticipation of a randomized controlled trial (RCT) to further validate the intervention, this qualitative descriptive analysis provides insights garnered from a patient/community/stakeholder-advisory board (PCS-AB, HEALERS) focus group series, convened to inform iterative refinements to a RCT protocol.

Hidden white and black feather layers enhance plumage coloration in tanagers and other songbirds.

Birds are renowned for their diverse and colorful plumage. Here, we demonstrate that vibrant plumage in the tanager genus is substantially intensified by a "hidden" layer of achromatic (white or black) plumage concealed beneath the outermost colorful layer. Using hyperspectral imaging, multispectral photography, microspectrophotometry, reflectance spectrophotometry, and optical modeling, we show that hidden white and black feather layers are systematically distributed on the body to enhance the brightness and saturation of carotenoid-pigmented and structurally colored plumage, respectively, by increasing or decreasing the amount of backscattered light that interacts with pigments or nanostructures.

Extracellular tau clearance is governed by its aggregation state and independent of microglial activation by LPS and IFN-γ.

Microglia are the tissue resident macrophages of the brain and their contribution to tau pathology progression remains to be fully understood. In this study, we developed a quantitative platform to elucidate the processing of extracellular tau within human induced pluripotent stem cell (iPSC)-derived microglia. We show that iPSC-derived microglia internalize monomeric and fibrillar tau through different cellular mechanisms and with different clearance kinetics.

Feather macrostructure is marginally correlated with temperature range but not urbanization across California.

Urban environments are often associated with resource and environmental differences providing potential novel selection pressures compared to adjacent unmodified landscapes. While these characteristics (e.g.

AvianLexiconAtlas: A database of descriptive categories of English-language bird names around the world.

Common names of species are important for communicating with the general public. In principle, these names should provide an accessible way to engage with and identify species. The common names of species have historically been labile without standard guidelines, even within a language.

Decoupling of Photocurrent and Dark Current for Extraordinary Detectivity in Uncooled Middle-Wavelength Infrared Nanohybrid Photodetectors.

Nanohybrids of graphene and colloidal semiconductor quantum dots (QDs/Gr) provide a promising quantum sensing scheme for photodetection. Despite exciting progress made in QDs/Gr photodetectors in broadband from ultraviolet to short-wave infrared, the device performance is limited in middle-wave infrared (MWIR) detection. A fundamental question arises as to whether the thermal noise-induced dark current and hence poor signal-to-noise ratio in conventional uncooled MWIR photodetectors persist in QDs/Gr nanohybrids.

Home-Based Cardiac Rehabilitation Among Attendees From a Large Health Care System During the Covid-19 Pandemic.

Background: Few studies have evaluated home-based cardiac rehabilitation (HBCR) during the pandemic, compared to prepandemic center-based CR (CBCR), with respect to patient characteristics, participation rates, and its efficacy on clinical metrics, health-related quality of life (QoL), and modifiable risk factors.

Objectives: We aimed to describe patient characteristics and participation rates for those attending HBCR compared to patients who attended CBCR and compare the effects of HBCR vs CBCR on clinical metrics, health-related QoL, and modifiable risk factors in CR patients pre vs during the COVID-19 pandemic.

Methods: A retrospective cohort study comparing 511 HBCR patients and 765 CBCR patients from the Mayo Clinic Health System.

Application of a novel deep learning-based 3D videography workflow to bat flight.

Studying the detailed biomechanics of flying animals requires accurate three-dimensional coordinates for key anatomical landmarks. Traditionally, this relies on manually digitizing animal videos, a labor-intensive task that scales poorly with increasing framerates and numbers of cameras. Here, we present a workflow that combines deep learning-powered automatic digitization with filtering and correction of mislabeled points using quality metrics from deep learning and 3D reconstruction.

Probing the Critical Role of Interfaces for Superior Performance in PbS Quantum Dot/Graphene Nanohybrid Broadband Photodetectors.

Colloidal quantum dots/graphene (QD/Gr) nanohybrids have been studied intensively for photodetection in a broadband spectrum including ultraviolet, visible, near-infrared, and shortwave infrared (UV-vis-NIR-SWIR). Since the optoelectronic process in the QD/Gr nanohybrid relies on the photogenerated charge carrier transfer from QDs to graphene, understanding the role of the QD-QD and QD-Gr interfaces is imperative to the QD/Gr nanohybrid photodetection. Herein, a systematic study is carried out to probe the effect of these interfaces on the noise, photoresponse, and specific detectivity in the UV-vis-NIR-SWIR spectrum.

A Fast, Reproducible, High-throughput Variant Calling Workflow for Population Genomics.

The increasing availability of genomic resequencing data sets and high-quality reference genomes across the tree of life present exciting opportunities for comparative population genomic studies. However, substantial challenges prevent the simple reuse of data across different studies and species, arising from variability in variant calling pipelines, data quality, and the need for computationally intensive reanalysis. Here, we present snpArcher, a flexible and highly efficient workflow designed for the analysis of genomic resequencing data in nonmodel organisms.

Efficacy and Adherence Rates of a Novel Community-Informed Virtual World-Based Cardiac Rehabilitation Program: Protocol for the Randomized Controlled Trial.

Background: Innovative restructuring of cardiac rehabilitation (CR) delivery remains critical to reduce barriers and improve access to diverse populations. is a novel virtual world technology-based CR program delivered through the virtual world platform, Second Life, which previously demonstrated high acceptability as an extension of traditional center-based CR. This study aims to evaluate efficacy and adherence of the virtual world-based CR program compared with center-based CR within a community-informed, implementation science framework.

The carotenoid redshift: Physical basis and implications for visual signaling.

Carotenoid pigments are the basis for much red, orange, and yellow coloration in nature and central to visual signaling. However, as pigment concentration increases, carotenoid signals not only darken and become more saturated but they also redshift; for example, orange pigments can look red at higher concentration. This occurs because light experiences exponential attenuation, and carotenoid-based signals have spectrally asymmetric reflectance in the visible range.

Metallic and Non-Metallic Plasmonic Nanostructures for LSPR Sensors.

Localized surface plasmonic resonance (LSPR) provides a unique scheme for light management and has been demonstrated across a large variety of metallic nanostructures. More recently, non-metallic nanostructures of two-dimensional atomic materials and heterostructures have emerged as a promising, low-cost alternative in order to generate strong LSPR. In this paper, a review of the recent progress made on non-metallic LSPR nanostructures will be provided in comparison with their metallic counterparts.

Aerobic response to thermal stress across ontogeny and habitats in a teleost fish.

Near-future climate change projections predict an increase in sea surface temperature that is expected to have significant and rapid effects on marine ectotherms, potentially affecting a number of critical life processes. Some habitats also undergo more thermal variability than others, and the inhabitants therefore must be more tolerant to acute periods of extreme temperatures. Mitigation of these outcomes may occur through acclimation, plasticity or adaptation, although the rate and extent of a species' ability to adjust to warmer temperatures is largely unknown, specifically as it pertains to effects on various performance metrics in fishes that inhabit multiple habitats throughout ontogenetic stages.

Assessing Youth Safety Knowledge through the Agriculture Experience Tracker (AET).

The purpose of this study was to assess high school agricultural education youth safety knowledge. The target population consisted of high school agricultural education youth, ages 14-19 years, who were enrolled in School Based Agricultural Education programs that utilized the AET agricultural safety exam feature between the dates of May 2019 and June 2020 (N=1478). The safety knowledge questions were randomly generated from the National Safe Tractor and Machinery Operation Program instructor curriculum resources.

Feather function and the evolution of birds.

The ability of feathers to perform many functions either simultaneously or at different times throughout the year or life of a bird is integral to the evolutionary history of birds. Many studies focus on single functions of feathers, but any given feather performs many functions over its lifetime. These functions necessarily interact with each other throughout the evolution and development of birds, so our knowledge of avian evolution is incomplete without understanding the multifunctionality of feathers, and how different functions may act synergistically or antagonistically during natural selection.

Case Investigation and Contact Tracing Efforts From Health Departments in the United States, November 2020 to December 2021.

Background: Sixty-four state, local, and territorial health departments (HDs) in the United States report monthly performance metrics on coronavirus disease 2019 (COVID-19) case investigation and contact tracing (CI/CT) activities. We describe national CI/CT efforts from 25 October 2020 through 24 December 2021, which included 3 peaks in COVID-19 case reporting.

Methods: Standardized CI/CT data elements submitted by the 64 HDs were summarized as monthly performance metrics for each HD and the nation.