Publications by authors named "Shui-Qin Cheng"
Clinical and morphologic spectrum of renal involvement in patients with HBV-associated cryoglobulinaemia.
Nephrology (Carlton)
June 2017
Article Synopsis
- The study aimed to explore the clinical and renal characteristics of patients with cryoglobulinaemic glomerulonephritis linked to hepatitis B virus (HBV) infection, as such cases are rarely reported.
- A total of 12 patients were analyzed; most exhibited nephrotic syndrome, with significant renal impairment and distinctive findings of cryoglobulinaemia, including various types and kidney pathology like membranoproliferative glomerulonephritis (MPGN).
- Despite treatment with antivirals and immunosuppressants, the study found a concerning prognosis, with many patients facing serious outcomes, highlighting the need for better detection and management of cryoglobulins in HBV-related kidney issues.
Article Synopsis
- The study compares the characteristics, treatment response, and outcomes of patients with IgA nephropathy and minimal change disease (MCD-IgAN) to those with classic minimal change disease (MCD).
- Both groups showed similar clinical symptoms, predominantly affecting young males with nephrotic syndrome, but MCD-IgAN patients had worse baseline kidney function and more severe kidney damage.
- After corticosteroid treatment, both groups had similar remission rates, and neither group progressed to end-stage renal disease during the follow-up period, although MCD-IgAN patients often required additional immunosuppressive treatment to achieve comparable outcomes.
Article Synopsis
- This study compares the characteristics and outcomes of patients with immunoglobulin A nephropathy and minimal change disease (MCD-IgAN) to those with immunoglobulin A nephropathy without minimal change disease (Non-MCD-IgAN).
- Results show that MCD-IgAN patients tend to be younger, experience less severe kidney damage, and have lower rates of end-stage renal disease (ESRD) compared to Non-MCD-IgAN patients.
- Overall, MCD-IgAN patients have a significantly better long-term renal prognosis, with only a small percentage reaching renal endpoints, unlike their Non-MCD-IgAN counterparts.