Publications by authors named "Shivam Shekhar"

Background And Aims: Rotator cuff (RC) disorders have a varied range of treatment. Multiple interventional, non-surgical treatments are often opted for by patients. This study evaluates the effectiveness of dextrose prolotherapy in treating RC pathologies.

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 During anesthesia induction, fluctuations in systemic hemodynamic may also alter cerebral hemodynamic, especially in patients with intracranial tumors, as these patients might have impaired cerebral autoregulation. This study compared the effects of ketofol (a mixture of ketamine and propofol) and etomidate on cerebral blood flow, oxygenation, and systemic hemodynamics during anesthesia induction for craniotomy in patients with supratentorial tumors.  This prospective, randomized, double-blind study included 50 patients aged 18 to 65 years, American Society of Anesthesiologists (ASA) classes I to II, undergoing elective craniotomy.

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Trans-Nasal Trans-Sphenoidal (TNTS) route has become the preferred conduit for operating on a surgically amenable pathology of pituitary gland. The procedure necessitates close monitoring of perioperative hemodynamic stability, especially in patients with impaired heart function. Patients with coronary artery disease (CAD) and compromized cardiac function with very low ejection fraction increase the risk of perioperative major adverse cardiac events (MACE).

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Article Synopsis
  • - C4 crops like maize and sorghum are more efficient at photosynthesis, water, and nitrogen use compared to C3 crops like rice, with both C3 and C4 crops containing the genes for C4 photosynthesis.
  • - A study compared the photosynthetic genes of C3 (rice), C4 (sorghum, maize, and foxtail millet), and CAM (pineapple) plants, revealing that C4 plants have the most genes for key enzymes while CAM had the fewest.
  • - The research showed that C4 gene expressions evolved with new tissue patterns in C4 crops, emphasizing the importance of gene expression in leaves and specific cellular distribution for efficient C4 photosynthesis development.
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  • The study compared the effects of dexmedetomidine and lignocaine on stress response, postoperative pain, and recovery in patients undergoing craniotomy for tumors, highlighting the importance of stable cerebral hemodynamics.
  • 105 patients were divided into three groups: one receiving dexmedetomidine, another receiving lignocaine, and a control group receiving normal saline, with all infusions administered during surgery.
  • Results indicated that dexmedetomidine was more effective than lignocaine in managing hemodynamic stability, brain relaxation, postoperative pain, and overall recovery, showing improved analgesia duration post-surgery.
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Introduction: Obstetric analgesia and anesthesia is a challenge in itself. It requires an understanding of the physiological changes during pregnancy and labor and the effect of anesthetic agents on the fetus and newborn. Because neuraxial techniques provide superior analgesia and materno-fetal benefits, their use have increased significantly over the past three decades or so.

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  • - The study investigates the effects of using alkalinized lignocaine 2% versus normal saline to fill endotracheal tube (ETT) cuffs during general anesthesia, aiming to reduce post-intubation complications like sore throat and nausea.
  • - High-volume low-pressure cuffs can cause damage to tracheal mucosa due to increased pressure from gas diffusion, and using lignocaine may help alleviate this irritation due to its local anesthetic properties.
  • - The research involved a randomized, double-blind trial with 120 participants, focusing on the benefits of lignocaine inflation in reducing post-intubation morbidities compared to saline.
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Non-operating room anesthesia challenges the anesthesiologist to deliver the same high-quality care as in the operating room. Amid the perplexity of the unfamiliar environment, scarcity of ancillary staff, and physical limitations, a distressing signal from pulse oximetry can cause a scare. We present a case of Raynaud's phenomenon in a patient posted for cystogastrostomy in the endoscopic retrograde cholangiopancreatography suite.

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Transverse myelitis is a rare inflammatory neurological disorder of the spinal cord that damages the myelin covering the spinal cord and thus produces sensory, motor, and autonomic symptoms. A 26-year-old primigravida of 40 weeks gestation presented to the obstetric emergency of our hospital with complaints of weakness in both lower limbs and inability to walk for four days. A diagnosis of acute transverse myelitis was made, and due to fetal distress and arrest of labor in the second stage, an emergency cesarean section was planned.

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