Comprehensive assessment of patients with Kawasaki disease without coronary artery aneurysm.

Background: In the current guidelines, the management algorithm for patients with Kawasaki disease (KD) without coronary artery (CA) aneurysms primarily depends on the clinical experience of pediatricians. It is necessary to conduct a comprehensive evaluation of these patients to provide a higher level of evidence for their management. Therefore, our study aimed to assess patients with KD using multidimensional data and investigate their prognosis.

Age-, Body Surface Area-, and Sex-Specific Reference Values for Pericardial Adipose Tissue in Children: An MRI Study.

Background: Pericardial adipose tissue (PAT) is a cardiovascular disease risk factor in children, but normative data for PAT thickness, area, and volume are lacking.

Purpose: To establish the percentile reference values for MRI PAT parameters in healthy Chinese children aged 3-18.

Study Type: Prospective.

Pericoronary Adipose Tissue CT Attenuation in Kawasaki Disease and Association with Coronary Artery Aneurysms, Myocardial Perfusion, and Coronary Events.

Purpose To evaluate coronary inflammation using pericoronary adipose tissue (PCAT) CT attenuation in patients with Kawasaki disease (KD) and determine the association of PCAT CT attenuation with coronary artery aneurysm (CAA), myocardial perfusion, and future coronary events (CEs). Materials and Methods This retrospective study included patients with KD and healthy controls who underwent coronary CT angiography (CCTA). Some patients also underwent cardiac MRI within 2 weeks of CCTA.

Association between left ventricular subclinical dysfunction and myocardial abnormalities in Kawasaki disease patients without coronary artery dilation.

Background: Previous studies have found that subclinical dysfunction was associated with coronary artery dilation in patients with Kawasaki disease. However, cardiac function and myocardial tissue characteristics have rarely been studied in Kawasaki disease patients without coronary artery dilation.

Objective: Our study aims to evaluate cardiac dysfunction and myocardial tissue characteristics in Kawasaki disease patients without coronary artery dilation using cardiac magnetic resonance imaging (MRI) and then investigate the association between subclinical dysfunction and myocardial abnormalities.

Correlation between cardiac and hepatic native T1 value and myocardial late gadolinium enhancement in children with Kawasaki disease.

Background: Kawasaki disease (KD) is an acute febrile illness and systemic vasculitis of unknown etiology that predominantly affects young children. The objective of this study was to investigate the correlation between myocardial and hepatic native T1 value and myocardial late gadolinium enhancement (LGE) in pediatric patients with KD.

Methods: In this cross-sectional retrospective study, 115 KD patients (50 in the acute phase, 65 in the chronic phase) and 40 age- and gender-matched controls underwent cardiac magnetic resonance (CMR) imaging with T1 mapping and LGE sequences.

Myocardial perfusion impairment in children with Kawasaki disease: assessment with cardiac magnetic resonance first-pass perfusion.

Background: Kawasaki disease (KD) potentially increases the risk of myocardial ischemia. This study aimed to semi-quantitatively evaluate myocardial perfusion impairment using cardiac magnetic resonance (CMR) first-pass perfusion in children with KD and explore the association between coronary artery (CA) dilation and myocardial perfusion.

Methods: From December 2018 to July 2021, 77 patients with KD (48 male, 5.

Comparison between diaphragmatic-navigated and self-navigated coronary magnetic resonance angiography at 3T in pediatric patients with congenital coronary artery anomalies.

Background: Coronary magnetic resonance angiography (CMRA) is being increasingly used in pediatric patients with congenital coronary artery anomalies (CAAs). However, the data on the free-breathing self-navigation technique, which has the potential to simplify the acquisition plan with a high success rate at 3T, remain scarce. This study investigated the clinical application value of self-navigated (sNAV) CMRA at 3T in pediatric patients with suspected CAAs and compared it to conventional diaphragmatic-navigated (dNAV) CMRA.

Self-navigated coronary MR angiography for coronary aneurysm detection in Kawasaki disease at 3T: comparison with conventional diaphragm-navigated coronary MR angiography.

Objectives: To assess the scan time, image quality, and diagnostic performance of self-navigated coronary MR angiography (SN-CMRA) for coronary aneurysm (CAA) detection in Kawasaki disease (KD) patients and compare it with diaphragm-navigated CMRA (DN-CMRA).

Materials And Methods: SN-CMRA and DN-CMRA were performed on 76 pediatric patients with KD (48 males, 6.75 ± 3.

Quantitative Assessment of Myocardial Edema by MR T2 Mapping in Children With Kawasaki Disease.

Background: Few studies assessed myocardial inflammation using Cardiovascular Magnetic Resonance Imaging in Kawasaki disease (KD) patients.

Purpose: To quantify myocardial edema in KD patients using T2 mapping and explore the independent predictors of T2 values.

Study Type: Prospective.

Effects of ABCA1 gene polymorphisms on risk factors, susceptibility and severity of coronary artery disease.

Background: The relationships between the rs1800976, rs4149313 and rs2230806 polymorphisms in ATP binding cassette protein A1 and severity of coronary artery disease (CAD) remain unclear.

Methods: Four hundred and forty-two patients with CAD and 217 CAD-free subjects were enrolled in this study. The rs1800976, rs4149313 and rs2230806 polymorphisms were genotyped by PCR-RFLP.