Normative Data on Platelet Count, Mean Platelet Volume, Platelet Distribution Width, Platelet-Large Cell Ratio, and Plateletcrit in Neonates.

Introduction Platelet indices, encompassing mean platelet volume (MPV), platelet distribution width (PDW), platelet-large cell ratio (P-LCR), and plateletcrit (PCT), along with platelet count, are fundamental for assessing the hematological health of neonates. In neonatal populations, especially within the first 28 days of life, establishing normative data on these indices is essential, as neonatal platelet physiology differs markedly from that of older children and adults. Elevated MPV can reflect an active bone marrow response to platelet consumption, while increased PDW may signify platelet anisocytosis and variation due to bone marrow stress.

Assessment of Lung Function and Its Correlation With Iron Overload in Children With Thalassemia Major.

Introduction:  Thalassemia major is a genetic disorder characterised by defective red cell production. Due to the requirement of regular blood transfusions, these patients are at risk of iron overload, leading to iron deposition in all organs, including the lungs, causing hemosiderosis of the lung, thereby causing impairment of lung function.

Objectives: The primary objective was to assess lung dysfunction in children with thalassemia major and to correlate it with serum iron status.

Establishing Normative Values of Peak Expiratory Flow Rates in the Paediatric Population in Jharkhand.

Background The peak expiratory flow rate (PEFR) is the maximum flow rate (expressed as L/s) generated during a forceful exhalation, starting from full inspiration. It is an effort-dependent parameter and reflects large airway flow. It depends on lung recoil, muscular strength of patients, and voluntary effort.