Understanding frailty in aging: a multidimensional perspective from Northern Iran.

Background: The global aging population is increasing rapidly, positioning frailty as a significant health concern among older adults. Despite its significance, data on the prevalence and determinants of frailty among community-dwelling older adults in Iran remain limited. This study aimed to assess the prevalence of frailty and identify its associated factors among older adults attending primary healthcare centers in Sari, Iran, using the Tilburg Frailty Indicator (TFI).

Investigation of radiation-induced xerostomia: cross-cultural adaptation and psychometric properties of the Persian version of the Xerostomia Questionnaire (P-XQ) among older head and neck cancer patients.

Background And Purpose: Dry mouth (xerostomia) is one of the most common early and late side effects of Head and Neck Cancer (HNC) survivors, despite advances in radiotherapy planning and administration. Given the major influence of xerostomia on cancer patients' quality of life, this study examined the psychometric features of the Persian version of the Xerostomia Questionnaire (P-XQ) in older Iranian HNC patients.

Methods: Conducted between April and June 2024, this methodological study used convenience sampling at the Iran Cancer Institute in Tehran, Iran.

Oral Health Assessment: Cross-Cultural Adaptation and Psychometric Properties of the Persian Version of the Oral Assessment Sheet (P-OAS) among Older Adults.

Background: Oral health plays a crucial role in personal, social, and psychological well-being, especially in older adults. Currently, no specific assessment tool is available in Iran that provides a multi-dimensional clinical assessment of oral health status. Therefore, this study aimed to examine the psychometric properties and cross-cultural adaptation of the Persian version of the Oral Assessment Questionnaire (P-OAS) for older adults.

Cross-Cultural Adaptation and Psychometric Properties of the Persian Version of the Spiritual Distress Scale (P-SDS) Among Older Adults with Cancer in Iran.

Spiritual health integrates physical, mental, and social aspects of life and helps adapt to disease. This study aimed to assess the psychometric properties of the Spiritual Distress Scale (SDS) in Iranian older adults diagnosed with cancer, as no existing measure was available in Iran. Conducted between May and July 2024, this methodological study used convenience sampling at the Cancer Institute in Tehran, Iran.

Association Between Oral Health Status and DMFT Index with Cognitive Dysfunction in Community-Dwelling Older Adults with Type 2 Diabetes: A Cross-Sectional Study.

Objective: Cognitive dysfunction is a significant issue in old age and can cause many problems in older adults, especially those with diabetes. This study aimed to investigate the association between oral health status and DMFT index with cognitive dysfunction in community-dwelling older adults with T2D (type 2 diabetes).

Methods: This was a cross-sectional study that included 245 older people aged 60 years and older with T2D, visiting healthcare centers in north of Iran, using the cluster sampling method.

The impact of theory-based education on promoting urinary tract infection prevention behaviours among elderly diabetic women - experimental study.

Introduction: Urinary tract infection (UTI) is a prevalent infection among the elderly population, often culminating in more severe and life-threatening complications. The prevalence of diabetes among elderly individuals is markedly on the rise, with UTI emerging as the most prevalent infectious ailment in this diabetic cohort. This study aims to ascertain the influence of theory-based education on promoting UTI prevention behaviours among elderly diabetic women.

Cross-cultural adaptation and psychometric properties of the Persian version of the Geriatric Sleep Questionnaire (P-GSQ).

Objective: This study aimed to validate the Geriatric Sleep Questionnaire (GSQ) for assessing subjective sleep quality among elderly individuals in Iran.

Methods: The GSQ underwent evaluation for face and content validity. Participants were selected via convenience sampling from five healthcare centers.

An Exploration of Some Predictors of Quality of Life-Related to the Innate Immune System, Inflammation, and Disease Activity in Patients with Behcet's Syndrome: An Analytical Cross-sectional Study.

Background: Behçet's disease (BD) has a growing prevalence in Silk Road countries. The aim of our cross-sectional study was to explore the clinical and molecular predictors of quality of life in BD patients.

Materials And Methods: One hundred and fifty consecutive Iranian BD patients with an age range between 20-50 years were included.

Mediating Roles of Stress, Anxiety, and Depression in the Relationship between Constipation and Sleep Quality among the Elderly: Structural Equation Modeling (SEM).

 Sleep quality is an important health index in the elderly. As age increases, changes occur in sleep quality leading to sleep disorders and recurrent complaints. Sleep quality management of the elderly requires identification of its determinants.

The effect of transcranial photobiomodulation on cognitive function and attentional performance of older women with mild cognitive impairment: a randomized controlled trial.

Introduction: Mild cognitive impairment (MCI) is a progressive age-related condition caused by physiological and structural changes in the brain, such as neurodegeneration and hypometabolism. Transcranial photobiomodulation (tPBM) is a neuromodulation technique that improves brain metabolism and oxygenation by irradiating red to near-infrared light on a specific area of the head. This study aimed to investigate the effect of multi-session tPBM on the cognitive capacities and attentional function of older women with MCI.

Cognitive and balance performance of older adult women during COVID-19 pandemic quarantine: an ex post facto study.

Introduction: Isolation and self-quarantine can expose individuals, particularly older people, to cognitive and physical decline. Due to a reduction in their musculoskeletal and neural flexibility, older adults are more likely to be affected by quarantine limitations. This study aimed to investigate the effect of self-quarantine on cognitive and balance performance of older women during the COVID-19 outbreak.

Factor affecting the activities of daily living among aging people during the COVID-19 pandemic - a structural equation modelling.

Introduction: The activities of daily living (ADLs) are a set of basic skills necessary for self-care. The inability of elderly people to perform ADLs leads to dependence, insecure conditions, and poor quality of life. The COVID-19 pandemic has affected all aspects of the daily life of the elderly.

Regulation of NLRP3 inflammasome by zinc supplementation in Behçet's disease patients: A double-blind, randomized placebo-controlled clinical trial.

Background: Overproduction of NLRP3 inflammasome complex is one of the causes of Behcet's disease's (BD) auto-inflammatory nature. The aim of current study was to examine the effect of zinc supplementation on NLRP3 inflammasome expression; as well as clinical manifestations of BD.

Methods: In this double-blind parallel placebo-controlled randomized clinical trial, 50 BD patients were randomly allocated into either zinc gluconate (30 mg/day elemental zinc) or placebo groups for 12 weeks.

Profiling inflammatory and oxidative stress biomarkers following taurine supplementation: a systematic review and dose-response meta-analysis of controlled trials.

Taurine (Tau) has modulatory effects on inflammatory and oxidative stress biomarkers; however, the results of clinical studies are not comprehensive enough to determine the effect of different durations and doses of Tau supplementation on inflammatory and oxidative stress biomarkers. The current study was conducted based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. For this purpose, PubMed/Medline, Scopus, and Embase databases were systematically searched to obtain the relevant studies published before 30th March 2021.

Evaluation of a Persian version of the Adelaide driving self-efficacy scale among Iranian older adults.

Objective: Our aim in the present study was to estimate the psychometric properties of the full-length Adelaide driving self-efficacy scale (ADSES) for use among community-based resident older adults in Tehran, Iran.

Methods: We recruited older adults (60+ years) from various sampling units nested in the Tehran district's general urban population (20 subjects/questionnaire-item). The questionnaire was translated and back-translated by using recommended pathways.

A comprehensive insight into the potential effects of resveratrol supplementation on SIRT-1: A systematic review.

Background And Aims: Silent information regulator 1 (Sirt1) involved in histone stability, transcriptional activity, and translocation. This systematic review aimed to summarize the effects of Resveratrol on Sirt1 expression.

Materials And Methods: Electronic databases including Scopus, Medline and web of knowledge were searched up to March 2020.

The effects of Cuminum cyminum on glycemic parameters: A systematic review and meta-analysis of controlled clinical trials.

Ethnopharmacological Relevance: Cuminum Cyminum (CC) is a traditional herbal medicine using as an antiseptic, anti-carcinogenic, anti-mutagenic, anti-cancer, anti-hypertensive, anti-inflammatory, and antioxidant. Recently hypoglycemic characteristics of CC have been indicated.

Aim Of The Study: We intended to conduct a meta-analysis on the effect of CC supplementation on glycemic parameters in patients with different chronic diseases.

Multiple factors associated with life satisfaction in older adults.

Introduction: The population of older adults is increasing as science progresses and health conditions improve. Social, psychological and behavioral factors will influence life satisfaction in older adults. We aimed to assess multiple factors associated with life satisfaction in older adults in Qom city, Iran.

Relationship between Life Satisfaction and Sleep Quality and Its Dimensions among Older Adults in City of Qom, Iran.

: Assessment of sleep quality is necessary in the older adults' management program so that good sleep quality will lead to a successful older adult's life. The present study aims to determine the relationship between life satisfaction and quality of sleep and its dimensions among the older adults' population residing in Qom city, Iran.: This was a cross-sectional descriptive-analytic study conducted in 2018.