Identification of optimal classifier and sensor placement for fall risk classification using IMU-based gait data.

Background: Fall risk can be classified using gait data collected from inertial measurement units (IMU). However, the optimal classifier and placement of IMU sensors to maximize classification performance have not yet been suggested.

Research Question: Is there an optimal IMU application strategy that yields the highest accuracy for classifying fall risk during gait?

Methods: Ninety-three community-dwelling older adults were grouped into low or high risk of a fall.

Korean red ginseng () root extract for the green synthesis of gold nanoparticles: assessment of cell viability and catalytic activity.

Mass spectrometry-based profiling of Korean red ginseng () root extracts by high-resolution LC-ESI-TOF-MS was conducted to identify the constituting compounds including ginsenosides, terpenoids and sugars. The constituting compounds were identified by accurate mass measurement and MS/MS patterns. Both extracts were successfully applied for the synthesis of gold nanoparticles (AuNPs).

Radiomics Models to Predict Tumor Response and Pneumonitis in Non-Small Cell Lung Cancer Patients Treated with Immunotherapy.

Checkpoint inhibitor-associated pneumonitis (CIP) after immunotherapy has become a challenging issue in non-small cell lung cancer (NSCLC) patients. This study leverages artificial intelligence (AI) algorithms to analyze radiomic features, aiming to predict the occurrence of CIP, as well as tumor response. This study analyzed data from 159 stage III-IV NSCLC patients undergoing immunotherapy.

Digital removal of dermal denticle layer using geometric AI from 3D CT scans of shark craniofacial structures enhances anatomical precision.

Craniofacial morphometrics in sharks provide crucial insights into evolutionary history, geographical variation, sexual dimorphism, and developmental patterns. However, the fragile cartilaginous nature of shark craniofacial skeleton poses significant challenges for traditional specimen preparation, often resulting in damaged cranial landmarks and compromised measurement accuracy. While computed tomography (CT) offers a non-invasive alternative for anatomical observation, the high electron density of dermal denticles in sharks creates a unique challenge, obstructing clear visualization of internal structures in three-dimensional volume-rendered images (3DVRI).

Identifying the best window size, lead time and sensor combination for classification of injurious versus non-injurious patient transfer from bed to wheelchair.

BackgroundPatient transfers are frequent occupational tasks of caregivers, often leading to lower back injuries. While early detection of injurious moments during patient transfers is helpful to lower the risk of such injuries, it remains a critical challenge.ObjectiveWe developed a classification model for injurious and non-injurious patient transfers using a support vector machine (SVM) with inertial measurement unit (IMU) sensor data of caregivers.

C24 Ceramide Lipid Nanoparticles for Skin Wound Healing.

: C24 ceramide plays a crucial role in skin regeneration and wound healing; however, its hydrophobic nature limits its application in therapeutic formulations. This study aims to enhance the bioavailability and efficacy of C24 ceramide by developing ceramide-based lipid nanoparticles (C24-LNP) and evaluate their impact on skin regeneration and wound healing. : C24-LNP was synthesized and characterized for aqueous stability and bioavailability.

Redox-Mediated Pyrene Electrolytes for Enhancing the Reversibility of Vertically Arranged Tin Electrodes in Seawater Batteries.

Seawater batteries (SWBs) have emerged as a next-generation battery technology that does not rely on lithium, a limited resource essential for lithium-ion batteries. Instead, SWBs utilize abundant sodium from seawater, offering a sustainable alternative to conventional battery technologies. Previous studies have demonstrated the feasibility of achieving high energy densities in SWB anodes using vertically aligned electrodes.

: A Framework for Discerning Services on Remote Medical Devices.

In the medical domain, computer systems in digital healthcare have increased connectivity continuously and the Message Service Element (DIMSE) protocol has a critical role in exchanging biomedical imaging data among different digital healthcare systems. As the data communication technology is used to handle sensitive information such as patient information (e.g.

Intra-arterial contrast enhanced computed tomography of the deep digital flexor tendon and palmar veins in the distal forelimb in Jeju horses: Evaluating contrast-enhancing factors.

Background: Few studies have investigated the adequate contrast enhancement (CE) evaluation depending on concentration, volume, and rate of administration of contrast media (CM) and the scan parameters in equine contrast enhanced computed tomography (CECT).

Objectives: To investigate CE of the deep digital flexor tendon (DDFT) and veins depending on the computed tomography (CT) voltage and concentration, volume, and rate of CM administration during intra-arterial CECT of equine distal forelimbs.

Study Design: In vivo experiments.

Effects of Short-Term Differences in Concentrate Feeding on the Recovery of In Vivo Embryos in Hanwoo Donor Cows through Superovulation Treatment.

Superovulation is a technique used to increase the number of oocytes released for fertilization. This study investigated the effects of short-term differences in concentrate feed intake on in vivo embryo production through superovulation in indigenous Korean (Hanwoo) cows. The cows were given fresh water and hay ad libitum and randomly divided into three groups (control (CON, n = 9): 2.

Novel Gammaherpesvirus Infections in Narrow-Ridged Finless Porpoise () and False Killer Whales () in the Republic of Korea.

A female narrow-ridged finless porpoise () stranded on a beach on Jeju Island showed epithelial proliferative skin lesions on its body. Two false killer whales (), caught using nets near Gangneung and Samcheok, respectively, had multiple plaques on their penile epidermis. Histological examination of the epidermis revealed that all the lesions had common features, including accentuated rete pegs, ballooning changes, and eosinophilic intranuclear inclusion (INI) bodies.

Characterizing the Compressive Force at L5/S1 During Patient Transfer From Bed to Wheelchair.

The peak compressive forces at L5/S1 during patient transfers have been estimated. However, no study has considered the actual patient body weight that caregivers had to handle during transfers. We developed a simple kinematic model of lifting to address this limitation.

VEGF-C prophylaxis favors lymphatic drainage and modulates neuroinflammation in a stroke model.

Meningeal lymphatic vessels (MLVs) promote tissue clearance and immune surveillance in the central nervous system (CNS). Vascular endothelial growth factor-C (VEGF-C) regulates MLV development and maintenance and has therapeutic potential for treating neurological disorders. Herein, we investigated the effects of VEGF-C overexpression on brain fluid drainage and ischemic stroke outcomes in mice.

Development of virus-induced genome editing methods in Solanaceous crops.

Genome editing (GE) using CRISPR/Cas systems has revolutionized plant mutagenesis. However, conventional transgene-mediated GE methods have limitations due to the time-consuming generation of stable transgenic lines expressing the Cas9/single guide RNA (sgRNA) module through tissue cultures. Virus-induced genome editing (VIGE) systems have been successfully employed in model plants, such as and spp In this study, we developed two VIGE methods for Solanaceous plants.

Computed tomographic dimensions and densities of the normal eye in Jeju horses.

This study aimed to describe the computed tomographic (CT) dimensions and the contrast attenuation of the eye in Jeju horses and Thoroughbreds. We evaluated the CT images of 10 Jeju horses and 6 Thoroughbreds without ocular abnormalities to assess the ocular dimensions and contrast attenuation. The following measurements showed significant differences between Jeju horses and Thoroughbreds (P<0.

Exploring the Impact of ChatGPT Literacy on User Satisfaction: The Mediating Role of User Motivations.

The introduction of chat generative pretrained transformer (ChatGPT), the fastest growing large language model, has changed the landscape of artificial intelligence-human interaction in everyday life. As the social influence of ChatGPT increases, competencies in it become important life skills. This study aims to explore the determinants of ChatGPT user satisfaction to provide practical implications by suggesting a significant independent variable and mediators between the independent variable and user satisfaction.

Exploring horticultural traits and disease resistance in Capsicum baccatum through segmental introgression lines.

Segmental introgression and advanced backcross lines were developed and validated as important tools for improving agronomically important traits in pepper, offering improved sensitivity in detecting quantitative trait loci for breeding. Segmental introgression lines (SILs) and advanced backcross lines (ABs) can accelerate genetics and genomics research and breeding in crop plants. This study presents the development of a complete collection of SILs and ABs in pepper using Capsicum annuum cv.

Reversible Na Plating/Stripping with High Areal Capacity Using an Electroconductive Liquid Electrolyte System.

Anode-free sodium-metal batteries (AFSMBs) are promising candidates for maximizing energy density and minimizing cost and safety hazards in the absence of metallic sodium during cell assembly. The practical implementation of AFSMBs is hindered by the low cycling stability of Na-metal plating and stripping, particularly under high areal capacities, due to unstable solid electrolyte interphase (SEI) layer formation with electrolyte decomposition and inactive dead Na formation. Here, we proposed an electroconductive electrolyte system consisting of liquid electrolytes that accept electrons at a certain energy level and form electronically conductive and solid electrolytes that prevent internal short circuit through low electronic conductivity.

VEGF-C promotes brain-derived fluid drainage, confers neuroprotection, and improves stroke outcomes.

Unlabelled: Meningeal lymphatic vessels promote tissue clearance and immune surveillance in the central nervous system (CNS). Vascular endothelium growth factor-C (VEGF-C) is essential for meningeal lymphatic development and maintenance and has therapeutic potential for treating neurological disorders, including ischemic stroke. We have investigated the effects of VEGF-C overexpression on brain fluid drainage, single cell transcriptome in the brain, and stroke outcomes in adult mice.

Human vs. machine-like representation in chatbot mental health counseling: the serial mediation of psychological distance and trust on compliance intention.

This study examined a serial mediation mechanism to test the effect of chatbots' human representation on the intention to comply with health recommendations through psychological distance and trust towards the chatbot counselor. The sample of the study comprised 385 adults from the USA. Two artificial intelligence chatbots either with human or machine-like representation were developed.

Substrate Dependence of CdSe/ZnS Quantum-Dot Light-Emitting Diodes: A Comparative Study between Rigid Glass and Flexible Plastic Substrates.

The purpose of this study was to investigate the effect of substrate characteristics on the performance of quantum-dot light-emitting diodes (QLEDs) with the aim of developing high-performance flexible QLEDs. Specifically, we compared QLEDs made with a flexible polyethylene naphthalate (PEN) substrate to those made with a rigid glass substrate, using the same materials and structure except for the substrates. Our findings indicate that the PEN QLED had a 3.

Do Anthropomorphic Chatbots Increase Counseling Satisfaction and Reuse Intention? The Moderated Mediation of Social Rapport and Social Anxiety.

The growing demand for mental health services and artificial intelligence chatbots to replace human agents have led to increased attention to chatbot anthropomorphizing. This study explored the effect of anthropomorphism on counseling satisfaction and reuse intention for chatbot-led mental health counseling and the mediating role of social rapport in the relationship. This study also examined the interaction effect of anthropomorphism and social anxiety on counseling satisfaction and reuse intention.

Effect of AI chatbot emotional disclosure on user satisfaction and reuse intention for mental health counseling: a serial mediation model.

This study explored the effect of chatbot emotional disclosure on user satisfaction and reuse intention for a chatbot counseling service. It also examined the independent and sequential mediation roles of user emotional disclosure intention and perceived intimacy with a chatbot on the relationship between chatbot emotional disclosure, user satisfaction, and reuse intention for chatbot counseling. In total, 348 American adults were recruited to participate in a mental health counseling session with either of the two types of artificial intelligence-powered mental health counseling chatbots.

Influence of Zika virus 3'-end sequence and nonstructural protein evolution on the viral replication competence and virulence.

Zika virus (ZIKV) has been circulating in human networks over 70 years since its first appearance in Africa, yet little is known about whether the viral 3'-terminal sequence and nonstructural (NS) protein diverged genetically from ancient ZIKV have different effects on viral replication and virulence in currently prevailing Asian lineage ZIKV. Here we show, by a reverse genetics approach using an infectious cDNA clone for a consensus sequence (Con1) of ZIKV, which represents Asian ZIKV strains, and another clone derived from the MR766 strain isolated in Uganda, Africa in 1947, that the 3'-end sequence -UUUCU-3' homogeneously present in MR766 genome and the -GUCU-3' sequence strictly conserved in Asian ZIKV isolates are functionally equivalent in viral replication and gene expression. By gene swapping experiments using the two infectious cDNA clones, we show that the NS1-5 proteins of MR766 enhance replication competence of ZIKV Con1.