Publications by authors named "Seynabou Diouf Sene"
Article Synopsis
- * A study conducted in Senegal analyzed the genetic diversity of PfCyRPA in 95 malaria isolates, finding a mostly common wild type allele, with 15 identified single nucleotide polymorphisms (SNPs), mostly appearing as unique changes.
- * Structure-based modeling showed that while most SNPs have minor effects on PfCyRPA antibodies, some may significantly affect its structure or interaction with the viral protein PfRH5, providing insights for future malaria vaccine design.
Background: Measuring malaria transmission intensity using the traditional entomological inoculation rate is difficult. Antibody responses to mosquito salivary proteins like SG6 have been used as biomarkers of exposure to Anopheles mosquito bites. Here, we investigate 4 mosquito salivary proteins as potential biomarkers of human exposure to mosquitoes infected with Plasmodium falciparum: mosGILT, SAMSP1, AgSAP, and AgTRIO.
View Article and Find Full Text PDFBackground: Measuring malaria transmission intensity using the traditional entomological inoculation rate is difficult. Antibody responses to mosquito salivary proteins such as SG6 have previously been used as biomarkers of exposure to mosquito bites. Here, we investigate four mosquito salivary proteins as potential biomarkers of human exposure to mosquitoes infected with : mosGILT, SAMSP1, AgSAP, and AgTRIO.
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