Optimal Interval of Screening Endoscopy for Reducing Gastric Cancer Mortality: A Nationwide Cohort Study.

Background And Aims: The optimal endoscopic screening interval for gastric cancer (GC) has not yet been established. We compared survival outcomes in patients with GC based on their history of endoscopic screening prior to diagnosis.

Methods: Using the Korean national insurance claims data, we identified all patients newly diagnosed with GC in 2010.

[Gastrojejunocolic Fistula: A Late Complication After Gastrojejunostomy].

Gastrojejunocolic fistula, a rare but serious complication of gastrojejunostomy often results from inadequate resection or incomplete vagotomy during gastric surgery. The most common symptoms include feculent vomiting, chronic diarrhea, and weight loss, and surgical repair is the definitive treatment for this condition. A 51-year-old man presented to our hospital with upper abdominal pain and chronic diarrhea.

Gastric Lipomatosis: A Case Report.

Gastric lipomatosis is a rare condition in which multiple lipomas develop in the stomach. We herein describe a 52-year-old woman diagnosed with gastric lipomatosis without any symptoms. The patient was incidentally diagnosed with gastric lipomatosis on endoscopy and computed tomography four years previously.

Tranilast Treatment Prevents Chronic Radiation-Induced Colitis in Rats by Inhibiting Mast Cell Infiltration.

Introduction: Mast cells are the principal cells involved in acute and chronic colitis due to radiation, known as radiation-induced colitis (RIC). In this study, we investigated whether pretreatment with tranilast, a mast cell inhibitor, could alleviate chronic RIC.

Methods: A total of 23 Sprague-Dawley rats were randomly divided into three groups: control group (n = 5), radiation group (RG, n = 9), and tranilast-pretreated radiation group (TG, n = 9).

A Case of Sporadic Multiple Colonic Polyps in a Young Woman.

Sporadic colorectal cancer arises from an adenoma. As mutations in the adenomatous polyposis coli (APC) tumor suppressor gene have been frequently detected in colorectal adenomas, the APC gene is considered a gatekeeper in colorectal carcinogenesis. Here, we report a case of sporadic multiple colonic adenomas that were accompanied by an APC-truncating mutation.