Non-invasive management of Thandaga vaatham (lumbar spondylosis) through Siddha Varmam therapy - A case report.

A 32-year-old female homemaker came with a complaints of chronic low back pain, radiating to both lower limbs, stiffness especially in the morning difficulty in walking and standing with intensified pain during household chores for two years. She was diagnosed with Tantaka vātam, one of the eighty types of vātam disease which is equivalent to lumbar spondylosis. She was treated with therapeutic Varmam manipulations in every 7 days for a period of 48 days and followed for six months.

Molecular docking analysis of aldose reductase with herbal compounds from selected siddha medicine for anti-cataract treatment.

Cataracts are a major cause of blindness and it is due to protein aggregation in the eye lens that is accelerated by aldose reductase (AR)-induced sorbitol accumulation. Therefore, it is of interest to evaluate the anti-cataract potential of six phytochemicals from Siddha medicinal herbs (carinol, voacangine, berberine, piperine, sesamin and isoamericanin A) using molecular docking analysis with human aldose reductase (PDB ID: 4GCA) where epalrestat is used as the standard compound. Analysis shows that berberine, piperine, sesamin and carinol have optimal binding interactions with aldose reductase, performing similar to the standard drug epalrestat having estimated free energy values of -10.

Effectiveness of Family Focused Psychiatric Nurse-Led Programs on Functional Ability and Psychological Well-being in Bipolar Disorder Clients.

Introduction: Bipolar disorder is chronic in nature, causing episodes of severe mood swings, increased or decreased energy levels and activities, and having severe influences on social, vocational, and family life. According to estimates, more than 46 million persons suffer from this condition across the globe, and thus, treatment can be established when drugs are used along with other nondrug measures. This paper presents family-oriented intervention by psychiatric nursing as a means to enhance the capacity for functional ability and psychological health of patients diagnosed with the disorder.

Autogenic Relaxation: A Gateway to Improve Mental Health for the Elderly with Depression and Anxiety.

Background: Aging presents significant challenges to healthcare, particularly in the underdiagnosis of mental health conditions such as depression and anxiety. Non-pharmacological interventions like autogenic relaxation have been explored as potential therapeutic options for improving mental health outcomes in the elderly.

Objective: This study aimed to determine the effectiveness of autogenic relaxation in reducing symptoms of depression and anxiety among elderly individuals and to examine its correlation with demographic and clinical variables.