Impact of Diabetes Duration on Major Adverse Cardiac Events in Patients with Non-Obstructive Coronary Artery Disease.

Diabetes mellitus is a substantial risk factor for coronary artery disease (CAD). Diabetes duration is linked to clinical outcomes in CAD patients. This study aimed to investigate the impact of diabetes duration on major adverse cardiovascular and cerebrovascular outcomes, as well as all-cause mortality, in Korean patients diagnosed with non-obstructive CAD.

Efficacy and safety of YHC-BE-2040 on immune function: An 8-week, multicenter, randomized, double-blinded, and placebo-controlled study.

Background: Deer velvet (DV) extract, a traditional remedy in Eastern Asian medicine, holds potential as an immune modulator. This study aimed to investigate the effects of enzymatically digested DV extract, YHC-BE-2040 (HENKIV®), on cell-mediated immunity in a randomized controlled trial.

Methods: Healthy adults (N = 120), aged 40 to 70, were randomly assigned to receive either a high-dose (HD) or low-dose (LD) DV extract, or a placebo daily for 8 weeks.

Tobacco cessation: screening and interventions.

Background: Tobacco use has been the leading cause of disease and death in South Korea. Early detection of tobacco use and evidence-based interventions play pivotal roles in facilitating tobacco cessation.

Methods: In accordance with the earlier iterations of the Lifetime Health Maintenance Program (2009) and recent recommendations from the United States Preventive Services Task Force (USPSTF; 2021), two themes were chosen for investigation: the identification of and intervention for tobacco use.

Association between Homocysteine and Vitamin D Levels in Asymptomatic Korean Adults.

An increased homocysteine level is a risk factor for cardiovascular disease, venous thromboembolism, cerebrovascular disease, and chronic kidney disease. In addition, vitamin D deficiency is associated with coronary artery disease and metabolic disorders. The present study included data from 1375 adults (895 men and 480 women) with a mean age of 52.

Relationship between metabolically healthy obesity and coronary artery calcification.

There is a lack of consensus regarding universally accepted criteria for metabolic health (MH). A simple definition of MH was systematically derived in a recent prospective cohort study. The present cross-sectional study aimed to explore the applicability of these criteria in Korean population, using coronary calcification as an indicator of cardiovascular risk.

Sunflower seed extract supplementation reduces body fat in adults with obesity: A double-blind, randomized, placebo-controlled trial.

Obesity is an important public health problem and socioeconomic burden. We hypothesized that an intake of sunflower seed extract (SUN-CA) would decrease body fat and then investigated the effects and safety of SUN-CA intake on body fat in adults with obesity as an option for obesity treatment. In this double-blind, randomized, placebo-controlled study, 100 adults with body mass indices of 25 to 31.

Associations between Dietary Patterns and Metabolic Syndrome: Findings of the Korean National Health and Nutrition Examination Survey.

Metabolic syndrome (MetS) is a multifactorial cluster of metabolic disorders related to cardiovascular disease and type 2 diabetes mellitus. Diet and dietary patterns are significant factors in the development and management of MetS. The associations between dietary patterns (i.

Changes in the prevalence of metabolic syndrome in Korean adults after the COVID-19 outbreak.

Objectives: This study sought to reveal changes in the prevalence of metabolic syndrome (MetS) after the start of the coronavirus disease 2019 (COVID-19) pandemic and to identify the groups showing the greatest changes.

Methods: We compared the prevalence of MetS between 2017-2019 (i.e.

Sarcopenia in community-dwelling older adults is associated with the diversity and composition of the gut microbiota.

Sarcopenia is a prognostic indicator of negative consequences in older adults, including physical disability, frailty, and mortality. Few studies have investigated the associations between sarcopenia and the gut microbiota. We sought such associations in community-dwelling older adults aged ≥60 years.

Fat-to-muscle Ratio: A New Indicator for Coronary Artery Disease in Healthy Adults.

Coronary artery disease (CAD) is an important issue in public health. Previous studies have shown that the ratio of fat to muscle mass is a significant predictor of metabolic disease, and it is known to be associated with atherosclerosis. In this study, we evaluated the association between the fat-to-muscle ratio (FMR) and CAD in healthy adults.

Association between dietary protein intake and skeletal muscle mass in older Korean adults.

Purpose: We investigated the association of low and high daily protein intakes on skeletal muscle mass status in Korean adults aged 60 years and older.

Methods: This cross-sectional study used data from the Korean National Health and Nutrition Examination Survey conducted between 2008 and 2011. The participants' dietary protein intake was assessed using the 24-h dietary recall method and was classified as low (< 0.

Impact of dietary protein intake on the incidence of low muscle strength in middle-aged and older adults.

Background: A reduction in skeletal muscle strength is a prognostic indicator of negative consequences, such as physical disability, frailty, and mortality in older adults. Studies investigating associations between the risk of reduction in skeletal muscle strength and the amount of dietary protein which is a factor influenced muscle health are scarce, particularly in Asian populations. Therefore, we investigated the association between the amount and change in daily protein intake and the prospective risk of developing low skeletal muscle strength in middle-aged and older adults.

Fatigue and Mental Status of Caregivers of Severely Chronically Ill Patients.

Background And Aims: Fatigue is an unpleasant experience accompanied by functional deterioration involving both mental and physical factors. Caregivers of patients with severe illnesses who require long-term treatment often experience marked physical and mental fatigue. This study investigated the factors affecting fatigue among caregivers of patients with severe chronic diseases.

Associations of skeletal muscle mass with atherosclerosis and inflammatory markers in Korean adults.

Background: Several global studies have clarified the relationship of sarcopenia with inflammatory markers and atherosclerosis; however, these associations in Korean adults remain unclear. We evaluated whether low skeletal muscle mass is associated with atherosclerosis and inflammatory markers in Korean adults.

Methods: We analysed data from 1556 Korean adults who visited a Health Promotion Centre in South Korea.

Associations Between Mental Health, Quality of Life, and Obesity/Metabolic Risk Phenotypes.

Obesity is a risk factor for many health issues, as are metabolic abnormalities; all may affect mental health and one's health-related quality of life. Therefore, we investigated the association between obesity subtypes, considering both body weight and metabolic abnormalities, and the mental health and quality of life of a Korean population. We used data from the 2016 Korean National Health and Nutrition Examination Survey, a cross-sectional survey of Korean civilians, and data on a total of 6057 participants were analyzed.

Are There Differences in Hair Mineral Concentrations Between Metabolically Healthy and Unhealthy Obese Adults?

Obesity is a risk factor for metabolic syndrome, dyslipidemia, hypertension, insulin resistance, type 2 diabetes mellitus, and cardiovascular disease. However, obesity is not a homogenous state and not all subjects in an obese population are at an increased risk for metabolic abnormalities. Thus, obesity types can be subdivided into metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO) according to metabolic status.

Noninvasive Serum Fibrosis Markers are Associated with Coronary Artery Calcification in Patients with Nonalcoholic Fatty Liver Disease.

Background/aims: Advanced hepatic fibrosis is associated with cardiovascular disease (CVD) in patients with nonalcoholic fatty liver disease (NAFLD). We investigated the association between noninvasive serum fibrosis markers and the coronary artery calcium score (CACS) in subjects with NAFLD.

Methods: We analyzed 665 NAFLD subjects without chronic liver disease or heart disease between 2011 and 2015.

Associations between Macronutrient Intakes and Obesity/Metabolic Risk Phenotypes: Findings of the Korean National Health and Nutrition Examination Survey.

Obesity is a risk factor for many health issues, as are metabolic abnormalities. However, few studies have addressed the associations between obesity/metabolic risk phenotypes and dietary macronutrient intakes (carbohydrate, protein, and fat). Therefore, this study examined the associations between macronutrient intakes and obesity/metabolic risk phenotypes in a Korean population.

Serum folate and vitamin B levels are not associated with the incidence risk of atherosclerotic events over 12 years: the Korean Genome and Epidemiology Study.

Atherosclerosis, a common cause of atherosclerotic vascular diseases, is associated with several risk factors including hyperhomocysteinemia, and vitamin B and folate are involved in homocysteine metabolism; thus, serum folate and vitamin B status may be associated with the risk of atherosclerotic vascular diseases mediated by homocysteine plasma concentrations. Therefore, we hypothesized that low vitamin B and folate levels are related to higher risks of atherosclerotic vascular disease and investigated the risk of atherosclerotic vascular events in Korean adults with low serum vitamin B and folate levels. This population-based cohort study followed 421 subjects aged 40-69 years for 12 years, 2003-2014.

Association between carbohydrate intake and body composition: The Korean National Health and Nutrition Examination Survey.

Objective: Several studies have investigated the effects of dietary carbohydrate intake on body composition. However, the results are controversial and few studies have been conducted on an Asian population. The aim of this study was to investigate whether dietary carbohydrate intake is associated with body composition in Korean adults.

Abdominal Obesity is Associated With Lower Bone Mineral Density in Non-Weight-Bearing Site in Korean Men.

This research aimed to investigate the relationship between abdominal obesity and lower bone mineral density (BMD) at non-weight-bearing site in Korean men using data from the Korea National Health and Nutrition Examination Survey, which is a nationwide cross-sectional survey. The study population ( n = 5,941) was selected from the 2009-2010 survey. Abdominal obesity in men was defined as waist circumference ⩾ 90 cm.

Safety and tolerability of Korean Red Ginseng in healthy adults: a multicenter, double-blind, randomized, placebo-controlled trial.

Background: Korean Red Ginseng (KRG) has been used in Asia for its various biological effects, but no studies have investigated the safety of its long-term intake. Therefore, the present study evaluated the safety of KRG intake for 24 weeks.

Methods: We randomized 1,000 participants in a 1:1 ratio into two groups, which were treated daily with 2 g of KRG or a placebo for 24 weeks.

Associations among inflammation, mental health, and quality of life in adults with metabolic syndrome.

Background: Metabolic syndrome (MetS), a pro-inflammatory state, has become increasingly common worldwide and is a major risk factor for type 2 diabetes mellitus and cardiovascular disease. Recently, studies on the relationships among inflammation, mental health, quality of life, and other diseases have been conducted.

Methods: We investigated the relationship between serum high-sensitivity C-reactive protein (hs-CRP) levels, as an indicator of inflammation, and the quality of life and psychiatric symptoms of Korean adults with MetS.

Hypertension and risk of psoriasis incidence: An 11-year nationwide population-based cohort study.

Psoriasis is a chronic inflammatory skin disease that is characterized by T-cell mediated immune response, and has been known to increase the risk of developing hypertension. However, the risk of psoriasis in patients with hypertension is not clear. Therefore, we investigated the risk of psoriasis in patients with hypertension.