Publications by authors named "Samira Fard"
Background: Insufficient or excessive respiratory effort during acute hypoxemic respiratory failure (AHRF) increases the risk of lung and diaphragm injury. We sought to establish whether respiratory effort can be optimized to achieve lung- and diaphragm-protective (LDP) targets (esophageal pressure swing - 3 to - 8 cm HO; dynamic transpulmonary driving pressure ≤ 15 cm HO) during AHRF.
Methods: In patients with early AHRF, spontaneous breathing was initiated as soon as passive ventilation was not deemed mandatory.
Article Synopsis
- Ultrasound can effectively measure abdominal muscle thickening in mechanically ventilated patients, providing insight into muscle function and potential weaning outcomes.
- A study involving healthy subjects and ventilated patients found a correlation between muscle thickening and pressure during respiratory efforts, indicating the relevance of these measurements.
- Results showed that changes in abdominal muscle thickening during breathing trials could predict the likelihood of reintubation, highlighting the clinical importance of ultrasound in assessing patient readiness for weaning from ventilation.
The diaphragm is vulnerable to injury during mechanical ventilation, and diaphragm dysfunction is both a marker of severity of illness and a predictor of poor patient outcome in the ICU. A combination of factors can result in diaphragm weakness. Both insufficient and excessive diaphragmatic contractile effort can cause atrophy or injury, and recent evidence suggests that targeting an appropriate amount of diaphragm activity during mechanical ventilation has the potential to mitigate diaphragm dysfunction.
View Article and Find Full Text PDF