Publications by authors named "Annia F Schreiber"
Background: Ventilator-induced diaphragmatic dysfunction (VIDD) occurs in up to 60% of mechanically ventilated patients and prolongs ventilatory dependance. The consequences of VIDD are muscle atrophy, reduction of strength, and injury of muscle fibers. Atrophy and contractile activity of the diaphragm can be estimated by ultrasound muscle thickness and thickening fraction.
View Article and Find Full Text PDFLimited information exists about the epidemiology, outcomes, and predictors of weaning from mechanical ventilation in patients with spinal cord injury. Our aim was to investigate predictors of weaning outcomes for patients with traumatic spinal cord injury (tSCI) and develop and validate a prognostic model and score for weaning success. This was a registry-based, multicentric cohort study including all adult patients with tSCI requiring mechanical ventilation (MV) and admitted to one of the intensive care units (ICUs) of the Trauma Registry at St.
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- Prolonged mechanical ventilation significantly affects life expectancy for patients with spinal cord injuries (SCI), leading this systematic review to analyze weaning success, ventilation duration, and mortality rates.
- The review included 39 studies with 14,637 adult patients, mostly with cervical lesions, revealing varied outcomes based on whether patients were in ICUs or rehabilitation centers.
- Findings showed a 63% weaning success rate and 8% mortality in ICUs, while rehabilitation centers had an 82% success rate with only 1% mortality, indicating potential benefits of early rehab intervention, though inconsistencies in defining weaning success were noted.
Article Synopsis
- Ultrasound can effectively measure abdominal muscle thickening in mechanically ventilated patients, providing insight into muscle function and potential weaning outcomes.
- A study involving healthy subjects and ventilated patients found a correlation between muscle thickening and pressure during respiratory efforts, indicating the relevance of these measurements.
- Results showed that changes in abdominal muscle thickening during breathing trials could predict the likelihood of reintubation, highlighting the clinical importance of ultrasound in assessing patient readiness for weaning from ventilation.
Background: Humidification is a standard of care during invasive mechanical ventilation. Two types of devices are used for this purpose: heated humidifiers and heat-and-moisture exchangers (HME).
Aim: To compare the short-term physiologic effects of an active HME, with those of heated humidifiers and HMEs in terms of respiratory effort, ventilatory pattern, and arterial blood gases during invasive mechanical ventilation.
Background: Patients undergoing prolonged mechanical ventilation represent up to 15% of all patients requiring weaning from mechanical ventilation. Although recent guidelines have recommended including physiotherapy early during mechanical ventilation to speed the process of weaning, only indirect evidence supporting the use of physiotherapy is available for patients receiving prolonged mechanical ventilation. The aim of our study was to evaluate the effects of a physiotherapy program in subjects requiring prolonged mechanical ventilation and the correlates of successful weaning.
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