Diesel exhaust particles modulate bone remodeling and worsen osteoporosis: and investigations.

Air pollution poses significant risks to public health, with diesel exhaust particles (DEP) contributing to a variety of systemic effects, including potential impacts on bone metabolism. This study investigates DEP's osteogenic and bone toxic effects using both pre-osteoblast models and Zebrafish models under healthy and osteoporotic conditions. Pre-osteoblasts treated with DEP exhibited enhanced calcium deposition and upregulated osteogenic markers, including Runx2 and type I collagen, at 25-50 μg ml concentrations.

Graphene: A Multifaceted Carbon-Based Material for Bone Tissue Engineering Applications.

Tissue engineering is an emerging technological field that aims to restore and replace human tissues. A significant number of individuals require bone replacement annually as a result of skeletal abnormalities or accidents. In recent decades, notable progress has been made in the field of biomedical research, specifically in the realm of sophisticated and biocompatible materials.

Chitosan derived chito-oligosaccharides promote osteoblast differentiation and offer anti-osteoporotic potential: Molecular and morphological evidence from a zebrafish model.

This study delves into the potential of chito-oligosaccharides (COS) to promote osteoblast differentiation and prevent osteoporosis, utilizing experiments with mouse MSCs and the zebrafish model. The preliminary biocompatibility study affirms the non-toxic nature of COS across various concentrations. In the osteoblast differentiation study, COS enhances ALP activity and calcium deposition at the cellular level.

A Review of Commonly used Health-Related Quality of Life instruments in Gynecological Cancer Survivors.

The number of cancer survivors is increasing steadily due to an aging population, continuing improvement in early detection, and treatment. Comparative effectiveness studies and clinical trials are being done to assess late effects of treatment and health-related quality of life. This is in addition to long-term follow-up to assess survival.

Quality of life following a maternal near-miss event during the COVID-19 pandemic at a tertiary care center in South India.

Objective: To assess the quality of life (QoL) in women following a maternal near-miss event and to assess the women's attitude towards future fertility and their contraceptive choices.

Methods: A cross-sectional observational study was conducted in Government Medical College, Kozhikode, India among women who had experienced a near-miss event (n = 50) between January 1, 2020 and May 31, 2021 during the peak of the COVID-19 pandemic. The QoL was assessed using the WHO Quality of Life, BREF Version, questionnaire, which was administered to the consenting participants over phone.