The BaGdRuO double perovskite oxide demonstrates intriguing behavior, arising from competing antiferromagnetic (AFM) and ferrimagnetic (FiM) phases. Under the GGA++SOC scheme, the system exhibits an AFM ground state with a very small energy difference of -11.39 meV compared to the FiM one.
View Article and Find Full Text PDFGestational diabetes mellitus (GDM) is one of the commonly encountered medical disorders of pregnancy affecting women of childbearing age globally at an alarming rate and causing significant perinatal morbidity and adverse fetal outcomes. The intricate interchanges between genetic susceptibility, metabolic changes and environmental factors contribute to the altered β-cell function, insulin sensitivity and glucose metabolism leading to hyperglycaemia in pregnancy. However, the precise etiology of GDM remains incompletely understood.
View Article and Find Full Text PDFOpioid use disorder (OUD) is a chronic disease that remains difficult to treat, even with significant improvements in available medications. While current treatments work well for some, they often do not account for the unique needs of individual patients, leading to less-than-ideal results. Precision medicine offers a new path forward by tailoring treatments to fit each person's genetic, psychological, and social needs.
View Article and Find Full Text PDFBackground: Portulaca oleracea (PO), an annual succulent herb with global distribution, has been used medicinally since ancient times, earning the title "global panacea."
Aim: This study aimed to perform phytochemical screening, antioxidant and antimicrobial analysis of PO seeds, including GCMS analysis of methanolic extract and molecular docking for antimicrobial mechanisms.
Materials And Methods: PO seeds underwent phytochemical screening and methanolic extract analysis via DPPH, NO radical scavenging, and reducing power assays.
Permanent pacemaker implantation in patients with severe claustrophobia and a history of substance abuse presents unique anesthetic challenges. The balance between ensuring patient comfort and avoiding the risks associated with systemic sedation or general anesthesia requires careful planning. In this report, a regional anesthetic technique, the clavipectoral fascial plane block, was used to facilitate pacemaker insertion in a high-risk individual without the need for sedatives or opioids.
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