Association of Breathing Effort With Survival in Patients With Acute Respiratory Distress Syndrome.

Objectives: Invasive mechanical ventilation (IMV) is crucial for acute respiratory distress syndrome (ARDS) management, but mortality remains high. While spontaneous breathing is key to weaning, excessive respiratory effort may injure the lung and diaphragm. Most existing data on respiratory effort during IMV are based on brief periods of observation, potentially underestimating the burden of inappropriate efforts.

Establishing an Essential Dataset for Trauma Registry in LMICs: Insights From a Delphi Survey.

Background: Injury is a leading cause of morbidity and mortality globally, with 90% of deaths occurring in low-middle-income countries (LMICs). Establishing well-functioning trauma systems is crucial in LMICs, with a trauma registry being an integral component. This study used the Delphi Technique to gather insights from trauma experts on essential data variables for adult trauma registries in LMICs.

Endoscopic en bloc prostate enucleation: a propensity score matched analysis between greenlight enucleation of prostate (GreenLEP) vs holmium laser enucleation of prostate (HOLEP) outcomes and safety with a 12-month follow-up.

Purpose: Greenlight has been successfully used to treat BPH since 2010s; however, its role during GreenLEP is still under investigation, differently from holmium in HOLEP. Study aim is to compare GreenLEP and HOLEP.

Methods: Data for GreenLEP and HOLEP were prospectively collected in two referral centers since 2021.

Spiropyran-based glutamate nanovalve for neuronal stimulation.

One of the main challenges in medical applications is achieving precise spatial and temporal control over the release of active molecules, such as neurotransmitters. To address this issue, we engineered a nanovalve that can deliver active molecules on demand by activating or deactivating a light-sensitive chemical barrier. This valve is composed of a polymer containing a spiropyran moiety, which can switch from a hydrophobic to a hydrophilic state upon photo-stimulation.

Temporal dynamics of full-body ownership and vicarious touch sensations as inferred from embodying a virtual avatar.

Feeling a tactile sensation when observing a touch on an artificial body (Vicarious Touch, VT) and the illusion of full-body ownership (Full-body Ownership Illusion, FBOI) can be effectively induced using Virtual Reality (VR). However, the onset timing of these phenomena, particularly under visual-only stimulation, remains elusive. While prior research has focused on body-part ownership under visuotactile conditions, the temporal dynamics of VT in a full-body context remain underexplored.